<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Introduction</h3>
<p>In recent years, interest in human papillomavirus infections as a causative factor in epithelial cancer development has grown. Literature indicates that HPV involvement in malignant transformations in oral mucosa can vary significantly, from 0 up to 87%. The aim of our study was to detect the prevalence of salivary HPV infection among generally healthy adults.</p>
</sec>
<sec><h3>Materials and Methods</h3>
<p>The examination involved 139 patients, from whom 139 whole, 1.5ml saliva samples were obtained. HPV DNA was detected by the nested PCR technique. To visualize the PCR products electrophoresis reactions were carried out.</p>
</sec>
<sec><h3>Results</h3>
<p>Sample analysis showed that DNA for HPV was detected in 14 patients: 11 positive results were obtained from men, and 3 from women. This yields a high infection rate: 10.07%.</p>
</sec>
<sec><h3>Conclusions</h3>
<p>The HPV prevalence in the male group was more than twice as high as in the female group. Also, subclinical oral HPV infection was detected more frequently in young (19–39 years old) and older (=>60 years old) adults.</p>
</sec>
</abstract>

Introduction
In recent years, interest in human papillomavirus infections as a causative factor in epithelial cancer development has grown. Literature indicates that HPV involvement in malignant transformations in oral mucosa can vary significantly, from 0 up to 87%. The aim of our study was to detect the prevalence of salivary HPV infection among generally healthy adults.

Materials and Methods
The examination involved 139 patients, from whom 139 whole, 1.5ml saliva samples were obtained. HPV DNA was detected by the nested PCR technique. To visualize the PCR products electrophoresis reactions were carried out.

Results
Sample analysis showed that DNA for HPV was detected in 14 patients: 11 positive results were obtained from men, and 3 from women. This yields a high infection rate: 10.07%.

Conclusions
The HPV prevalence in the male group was more than twice as high as in the female group. Also, subclinical oral HPV infection was detected more frequently in young (19–39 years old) and older (=>60 years old) adults.

Salivary HPV infection in healthy people

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Salivary HPV infection in healthy people"}

Introduction
In recent years, interest in human papillomavirus infections as a causative factor in epithelial cancer development has grown. Literature...

Salivary HPV infection in healthy people

Article Category: Original Study

Published Online: May 29, 2022

Page range: 143 - 148

Received: Dec 30, 2020

Accepted: Aug 11, 2021

DOI: https://doi.org/10.2478/ahem-2022-0016

Keywords
human papillomavirus, saliva, healthy adults

© 2022 Małgorzata Radwan-Oczko et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Salivary HPV infection in healthy people

Article Category: Original Study

Published Online: May 29, 2022

Page range: 143 - 148

Received: Dec 30, 2020

Accepted: Aug 11, 2021

DOI: https://doi.org/10.2478/ahem-2022-0016

Keywordshuman papillomavirus, saliva, healthy adults

© 2022 Małgorzata Radwan-Oczko et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
human papillomavirus, saliva, healthy adults