<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Vitamin D is extremely important for the proper functioning of the body. The most commonly known role of vitamin D is its participation in regulation of calcium-phosphate metabolism and bone mineralization. This role is crucial in the prevention of rickets in children and osteoporosis in the elderly. In recent years, numerous studies have confirmed the pleiotropic effects of vitamin D. Proper vitamin D levels in blood have a positive effect on overall health, thus reducing the risk of many diseases. Vitamin D plays, inter alia, a positive role in some diseases of the gastrointestinal tract (inflammatory bowel disease), nervous system (Parkinson disease, Alzheimer disease), and cardiovascular disease (atherosclerosis). Additionally, its positive protective effect in the case of neoplastic and immunological diseases has been noted. Some studies also confirm the relationship of vitamin D deficiency to obesity and depression. In the event of these diseases, it is possible to prevent disease and support the process of treatment by maintaining appropriate levels of 25(OH)D in the blood. Besides, sufficient blood vitamin D levels reduces the risk of developing respiratory tract infections and suppresses cytokine storm, which is responsible for most COVID-19 deaths.</p>
<p>The aim of the study was to present the current state of knowledge regarding the role of vitamin D in the human body, especially in the context of the impact of its abnormal level on the development of various diseases.</p>
</abstract>

Vitamin D is extremely important for the proper functioning of the body. The most commonly known role of vitamin D is its participation in regulation of calcium-phosphate metabolism and bone mineralization. This role is crucial in the prevention of rickets in children and osteoporosis in the elderly. In recent years, numerous studies have confirmed the pleiotropic effects of vitamin D. Proper vitamin D levels in blood have a positive effect on overall health, thus reducing the risk of many diseases. Vitamin D plays, inter alia, a positive role in some diseases of the gastrointestinal tract (inflammatory bowel disease), nervous system (Parkinson disease, Alzheimer disease), and cardiovascular disease (atherosclerosis). Additionally, its positive protective effect in the case of neoplastic and immunological diseases has been noted. Some studies also confirm the relationship of vitamin D deficiency to obesity and depression. In the event of these diseases, it is possible to prevent disease and support the process of treatment by maintaining appropriate levels of 25(OH)D in the blood. Besides, sufficient blood vitamin D levels reduces the risk of developing respiratory tract infections and suppresses cytokine storm, which is responsible for most COVID-19 deaths.
The aim of the study was to present the current state of knowledge regarding the role of vitamin D in the human body, especially in the context of the impact of its abnormal level on the development of various diseases.

Health consequences of vitamin D deficiency in the human body

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Health consequences of vitamin D deficiency in the human body"}

Vitamin D is extremely important for the proper functioning of the body. The most commonly known role of vitamin D is its participation in regulation of...

Name or symbol	Other name, symbol, function
7-dehydrocholesterol	Provitamin-D₃ converted into cholecalciferol in the skin after UVB ray exposure
Cholecalciferol	Vitamin D₃ – vitamin D of animal origin, formed in human skin
Ergocalciferol	Vitamin D₂ – vitamin D of plant and mushroom origin
Calcifediol	Calcidiol; 25-hydroxycholecalciferol; 25(OH)D₃; 25-hydroxyvitamin D – vitamin D prohormone formed in the liver from cholecalciferol, long half-life in blood plasma, helps to detect vitamin D deficiency and excess
25(OH)D	The sum of isoform 25(OH)D₃ and 25(OH)D₂
Calcitriol	1,25(OH)₂D; 1,25-dihydroxyvitamin D – active form of vitamin D in the function of hormone, formed in the kidneys

Health consequences of vitamin D deficiency in the human body

Article Category: Review

Published Online: Feb 03, 2022

Page range: 947 - 958

Received: Jan 29, 2021

Accepted: Aug 19, 2021

DOI: https://doi.org/10.2478/ahem-2021-0045

Keywords
Vitamin D, deficiencies, autoimmune diseases, neurodegenerative diseases, depression, COVID-19

© 2021 Paweł Glibowski, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Symbols, names, and functions of vitamin D metabolites

Health consequences of vitamin D deficiency in the human body

Article Category: Review

Published Online: Feb 03, 2022

Page range: 947 - 958

Received: Jan 29, 2021

Accepted: Aug 19, 2021

DOI: https://doi.org/10.2478/ahem-2021-0045

KeywordsVitamin D, deficiencies, autoimmune diseases, neurodegenerative diseases, depression, COVID-19

© 2021 Paweł Glibowski, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Symbols, names, and functions of vitamin D metabolites

Keywords
Vitamin D, deficiencies, autoimmune diseases, neurodegenerative diseases, depression, COVID-19