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Preparation and evaluation of an oral mucoadhesive gel containing nystatin-loaded alginate microparticles


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Alipour, S., H. Montaseri, A. Khalili and M. Tafaghodi “Non-invasive endotracheal delivery of paclitaxel-loaded alginate microparticles.” J Chemother (2016).28(5): 411–416. AlipourS. MontaseriH. KhaliliA. TafaghodiM. “Non-invasive endotracheal delivery of paclitaxel-loaded alginate microparticles.” J Chemother 2016 28 5 411 416 10.1080/1120009X.2015.1105624 Search in Google Scholar

Conklin, R. J. and B. Blasberg “Common inflammatory diseases of the mouth.” Int J Dermatol (1991).30(5): 323–335. ConklinR. J. BlasbergB. “Common inflammatory diseases of the mouth.” Int J Dermatol 1991 30 5 323 335 10.1111/j.1365-4362.1991.tb03869.x Search in Google Scholar

Croy, S. R. and G. S. Kwon “The effects of Pluronic block copolymers on the aggregation state of nystatin.” J Control Release (2004).95(2): 161–171. CroyS. R. KwonG. S. “The effects of Pluronic block copolymers on the aggregation state of nystatin.” J Control Release 2004 95 2 161 171 10.1016/j.jconrel.2003.11.003 Search in Google Scholar

El-Kamel, A., O. Al-Gohary and E. Hosny “Alginate-diltiazem hydrochloride beads: optimization of formulation factors, in vitro and in vivo availability.” J Microencapsul (2003).20(2): 211–225. El-KamelA. Al-GoharyO. HosnyE. “Alginate-diltiazem hydrochloride beads: optimization of formulation factors, in vitro and in vivo availability.” J Microencapsul 2003 20 2 211 225 10.3109/02652040309178063 Search in Google Scholar

Helliwell, M. “The use of bioadhesives in targeted delivery within the gastrointestinal tract.” Adv Drug Deliv Rev (1993).11(3): 221–251. HelliwellM. “The use of bioadhesives in targeted delivery within the gastrointestinal tract.” Adv Drug Deliv Rev 1993 11 3 221 251 10.1016/0169-409X(93)90011-R Search in Google Scholar

Heng, P., L. Chan and T. Wong “Formation of alginate microspheres produced using emulsification technique.” J Microencapsulation (2003).20(3): 401–413. HengP. ChanL. WongT. “Formation of alginate microspheres produced using emulsification technique.” J Microencapsulation 2003 20 3 401 413 10.3109/02652040309178078 Search in Google Scholar

Lacy, C., L. L. Armstrong, M. P. Goldman and L. L. Lance (2004). Lexi-Comp's Drug information handbook international: with Canadian and international drug monographs, Lexi-Comp. LacyC. ArmstrongL. L. GoldmanM. P. LanceL. L. 2004 Lexi-Comp's Drug information handbook international: with Canadian and international drug monographs, Lexi-Comp Search in Google Scholar

Laffleur, F., G. Shahnaz, Z. Islambulchilar and A. Bernkop-Schnürch “Design and in vitro evaluation of a novel polymeric excipient for buccal applications.” Future Med Chem (2013).5(5): 511–522. LaffleurF. ShahnazG. IslambulchilarZ. Bernkop-SchnürchA. “Design and in vitro evaluation of a novel polymeric excipient for buccal applications.” Future Med Chem 2013 5 5 511 522 10.4155/fmc.13.3323573970 Search in Google Scholar

Lee, C.-H. and Y. W. Chien “In vitro permeation study of a mucoadhesive drug delivery system for controlled delivery of nonoxynol-9.” Pharm Dev Technol (1996).1(2): 135–145. LeeC.-H. ChienY. W. “In vitro permeation study of a mucoadhesive drug delivery system for controlled delivery of nonoxynol-9.” Pharm Dev Technol 1996 1 2 135 145 10.3109/108374596090298889552340 Search in Google Scholar

Llabot, J. M. and R. H. Manzo “Double-layered mucoadhesive tablets containing nystatin.” AAPS PharmSciTech (2002).3(3): 47–52. LlabotJ. M. ManzoR. H. “Double-layered mucoadhesive tablets containing nystatin.” AAPS PharmSciTech 2002 3 3 47 52 10.1208/pt030322278405112916937 Search in Google Scholar

Llabot, J. M., R. H. Manzo and D. A. Allemandi “Drug release from carbomer: carbomer sodium salt matrices with potential use as mucoadhesive drug delivery system.” Int J Pharm (2004).276(1–2): 59–66. LlabotJ. M. ManzoR. H. AllemandiD. A. “Drug release from carbomer: carbomer sodium salt matrices with potential use as mucoadhesive drug delivery system.” Int J Pharm 2004 276 1–2 59 66 10.1016/j.ijpharm.2004.02.00615113614 Search in Google Scholar

Llabot, J. M., S. D. Palma, R. H. Manzo and D. A. Allemandi “Design of novel antifungal mucoadhesive films: Part I. Pre-formulation studies.” Int J Pharm (2007).330(1): 54–60. LlabotJ. M. PalmaS. D. ManzoR. H. AllemandiD. A. “Design of novel antifungal mucoadhesive films: Part I. Pre-formulation studies.” Int J Pharm 2007 330 1 54 60 10.1016/j.ijpharm.2006.08.042 Search in Google Scholar

Llabot, J. M., S. D. Palma, R. H. Manzo and D. A. Allemandi “Design of novel antifungal mucoadhesive films: Part II. Formulation and in vitro biopharmaceutical evaluation.” Int J Pharm (2007).336(2): 263–268. LlabotJ. M. PalmaS. D. ManzoR. H. AllemandiD. A. “Design of novel antifungal mucoadhesive films: Part II. Formulation and in vitro biopharmaceutical evaluation.” Int J Pharm 2007 336 2 263 268 10.1016/j.ijpharm.2006.12.001 Search in Google Scholar

Madhav, N. S. and S. Kala “Review on microparticulate drug delivery system.” Int J PharmTech Res (2011).3(3): 1242–1244. MadhavN. S. KalaS. “Review on microparticulate drug delivery system.” Int J PharmTech Res 2011 3 3 1242 1244 Search in Google Scholar

Martín-Villena, M., F. Fernández-Campos, A. Calpena-Campmany, N. Bozal-de Febrer, M. Ruiz-Martínez and B. Clares-Naveros “Novel microparticulate systems for the vaginal delivery of nystatin: development and characterization.” Carbohydr Polym (2013).94(1): 1–11. Martín-VillenaM. Fernández-CamposF. Calpena-CampmanyA. Bozal-de FebrerN. Ruiz-MartínezM. Clares-NaverosB. “Novel microparticulate systems for the vaginal delivery of nystatin: development and characterization.” Carbohydr Polym 2013 94 1 1 11 10.1016/j.carbpol.2013.01.005 Search in Google Scholar

Martín, M. J., A. C. Calpena, F. Fernández, M. Mallandrich, P. Gálvez and B. Clares “Development of alginate microspheres as nystatin carriers for oral mucosa drug delivery.” Carbohydr Polym (2015).117: 140–149. MartínM. J. CalpenaA. C. FernándezF. MallandrichM. GálvezP. ClaresB. “Development of alginate microspheres as nystatin carriers for oral mucosa drug delivery.” Carbohydr Polym 2015 117 140 149 10.1016/j.carbpol.2014.09.032 Search in Google Scholar

Mohammadi-Samani, S., R. Bahri-Najafi and G. Yousefi “Formulation and in vitro evaluation of prednisolone buccoadhesive tablets.” Il Farmaco (2005).60(4): 339–344. Mohammadi-SamaniS. Bahri-NajafiR. YousefiG. “Formulation and in vitro evaluation of prednisolone buccoadhesive tablets.” Il Farmaco 2005 60 4 339 344 10.1016/j.farmac.2005.01.009 Search in Google Scholar

Netsomboon, K. and A. Bernkop-Schnürch “Mucoadhesive vs. mucopenetrating particulate drug delivery.” Eur J Pharm Biopharm (2016).98: 76–89. NetsomboonK. Bernkop-SchnürchA. “Mucoadhesive vs. mucopenetrating particulate drug delivery.” Eur J Pharm Biopharm 2016 98 76 89 10.1016/j.ejpb.2015.11.003 Search in Google Scholar

Østberg, T., E. M. Lund and C. Graffner “Calcium alginate matrices for oral multiple unit administration: IV. Release characteristics in different media.” Int J Pharm (1994).112(3): 241–248. ØstbergT. LundE. M. GraffnerC. “Calcium alginate matrices for oral multiple unit administration: IV. Release characteristics in different media.” Int J Pharm 1994 112 3 241 248 10.1016/0378-5173(94)90360-3 Search in Google Scholar

Roque, L., P. Castro, J. Molpeceres, A. S. Viana, A. Roberto, C. Reis, P. Rijo, I. Tho, B. Sarmento and C. Reis “Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies.” Eur Polym J (2018).104: 19–31. RoqueL. CastroP. MolpeceresJ. VianaA. S. RobertoA. ReisC. RijoP. ThoI. SarmentoB. ReisC. “Bioadhesive polymeric nanoparticles as strategy to improve the treatment of yeast infections in oral cavity: in-vitro and ex-vivo studies.” Eur Polym J 2018 104 19 31 10.1016/j.eurpolymj.2018.04.032 Search in Google Scholar

Sawant, B. and T. Khan “Recent advances in delivery of antifungal agents for therapeutic management of candidiasis.” Biomed Pharmacother (2017).96: 1478–1490. SawantB. KhanT. “Recent advances in delivery of antifungal agents for therapeutic management of candidiasis.” Biomed Pharmacother 2017 96 1478 1490 10.1016/j.biopha.2017.11.12729223551 Search in Google Scholar

Sean, C. S. and B. Paul “Martindale: the complete drug reference.” (2009). SeanC. S. PaulB. “Martindale: the complete drug reference.” 2009 Search in Google Scholar

Sudhakar, Y., K. Kuotsu and A. K. Bandyopadhyay “Buccal bioadhesive drug delivery — A promising option for orally less efficient drugs.” J Control Release (2006).114(1): 15–40. SudhakarY. KuotsuK. BandyopadhyayA. K. “Buccal bioadhesive drug delivery — A promising option for orally less efficient drugs.” J Control Release 2006 114 1 15 40 10.1016/j.jconrel.2006.04.01216828915 Search in Google Scholar

Tafaghodi, M. a., S. S. Tabasi and M. Jaafari “Formulation, characterization and release studies of alginate microspheres encapsulated with tetanus toxoid.” J Biomater Sci, Polym Ed (2006).17(8): 909–924. TafaghodiM. a. TabasiS. S. JaafariM. “Formulation, characterization and release studies of alginate microspheres encapsulated with tetanus toxoid.” J Biomater Sci, Polym Ed 2006 17 8 909 924 10.1163/15685620677799688017024880 Search in Google Scholar

Takka, F. A., S “Calcium alginate microparticles for oral administration: II effect of form ulation factors on drug release and drug entrapment efficiency.” J Microencapsul (1999).16(3): 291–301. TakkaF. A. S “Calcium alginate microparticles for oral administration: II effect of form ulation factors on drug release and drug entrapment efficiency.” J Microencapsul 1999 16 3 291 301 10.1080/02652049928902210340215 Search in Google Scholar

Ujević, A., L. Lugović-Mihić, M. Situm, L. Ljubesić, J. Mihić and N. Troskot “Aphthous ulcers as a multifactorial problem.” Acta Clinica Croatia (2013).52(2): 213–221. UjevićA. Lugović-MihićL. SitumM. LjubesićL. MihićJ. TroskotN. “Aphthous ulcers as a multifactorial problem.” Acta Clinica Croatia 2013 52 2 213 221 Search in Google Scholar

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