<abstract xmlns="http://www.w3.org/1999/xhtml"><p>In this study, it was aimed to synthesize hydrogel based antibacterial, biocompatible and non-toxic wound dressing materials by solvent removal method usingpoly(vinylalcohol) (PVA), poly(vinylpyrolidone) (PVP) and nano pomegranate seed (PN).The morphology, swelling capacity, contact angle, antibacterial activity, biocompatibility and cytotoxicity of the synthesized films were determined. From the experimental findings, it was found that the PN particles were nano-sized, showed homogeneous and spherical distribution and improved the hydrophobic properties of the materials obtained by the addition of PN. And also, their swelling capacities were decreased with increased PN amount and all of the materials showed similar antibacterial activity, hemocompatibility and cytotoxicity.</p></abstract>

In this study, it was aimed to synthesize hydrogel based antibacterial, biocompatible and non-toxic wound dressing materials by solvent removal method usingpoly(vinylalcohol) (PVA), poly(vinylpyrolidone) (PVP) and nano pomegranate seed (PN).The morphology, swelling capacity, contact angle, antibacterial activity, biocompatibility and cytotoxicity of the synthesized films were determined. From the experimental findings, it was found that the PN particles were nano-sized, showed homogeneous and spherical distribution and improved the hydrophobic properties of the materials obtained by the addition of PN. And also, their swelling capacities were decreased with increased PN amount and all of the materials showed similar antibacterial activity, hemocompatibility and cytotoxicity.

Synthesis, Characterization and Some Biological Properties of PVA/PVP/PN Hydrogel Nanocomposites: Antibacterial and Biocompatibility

Balıkesir Karesi Martyr Prof. Dr. İlhanVarank Science and Arts Center

Balikesir University Science and Technology Application and Research Center

Faculty of Science and Literature Department of Molecular Biology and Genetics

Advances in Materials Science

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

In this study, it was aimed to synthesize hydrogel based antibacterial, biocompatible and non-toxic wound dressing materials by solvent removal method...

Synthesis, Characterization and Some Biological Properties of PVA/PVP/PN Hydrogel Nanocomposites: Antibacterial and Biocompatibility

Published Online: Oct 11, 2019

Page range: 32 - 45

DOI: https://doi.org/10.2478/adms-2019-0015

Keywords
Pomegranate seed, hydrogel nanocomposite, wound dressing material, antibacterial activity

© 2019 E. E. Doğan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Synthesis, Characterization and Some Biological Properties of PVA/PVP/PN Hydrogel Nanocomposites: Antibacterial and Biocompatibility

Published Online: Oct 11, 2019

Page range: 32 - 45

DOI: https://doi.org/10.2478/adms-2019-0015

KeywordsPomegranate seed, hydrogel nanocomposite, wound dressing material, antibacterial activity

© 2019 E. E. Doğan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Pomegranate seed, hydrogel nanocomposite, wound dressing material, antibacterial activity