<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The aim of  this study was to determine and compare values of  carcinoembryonic antigen (CEA) and cancer antigen (CA 15-3) in 50 bitches with mammary tumors and 150 clinically healthy dogs. A modified procedure was used to determine the CEA and CA 15-3 markers with the human kits using the radioimmunoassay method (RIA). Samples collected from extirpated tumors of  mammary glands were histologically processed and classified as per WHO guidelines. The mean values of  the carcinoembryonic antigen markers ± SD were as follows: control group 0.89 ± 0.79, group with mammary gland tumor 1.53 ± 1.15. The values of  cancer antigen markers CA 15-3 ± SD were: 1.52 ± 0.66 and 2.87 ± 1.11, respectively. The statistical significance for the carcinoembryonic antigen marker between groups was P &lt; 0.0001. The cancer antigen CA 15-3 values between groups were also statistically significant with P &lt; 0.0001. The results of  the present study show that there are significant differences in both antigens between the control group and groups with mammary gland tumor in dogs.</p>
</abstract>

The aim of  this study was to determine and compare values of  carcinoembryonic antigen (CEA) and cancer antigen (CA 15-3) in 50 bitches with mammary tumors and 150 clinically healthy dogs. A modified procedure was used to determine the CEA and CA 15-3 markers with the human kits using the radioimmunoassay method (RIA). Samples collected from extirpated tumors of  mammary glands were histologically processed and classified as per WHO guidelines. The mean values of  the carcinoembryonic antigen markers ± SD were as follows: control group 0.89 ± 0.79, group with mammary gland tumor 1.53 ± 1.15. The values of  cancer antigen markers CA 15-3 ± SD were: 1.52 ± 0.66 and 2.87 ± 1.11, respectively. The statistical significance for the carcinoembryonic antigen marker between groups was P < 0.0001. The cancer antigen CA 15-3 values between groups were also statistically significant with P < 0.0001. The results of  the present study show that there are significant differences in both antigens between the control group and groups with mammary gland tumor in dogs.

Tumor Markers in Dogs with Mammary Gland Tumors

Institute of  Nuclear and Molecular Medicine (INMM)

Acta Veterinaria

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Tumor Markers in Dogs with Mammary Gland Tumors"}

The aim of  this study was to determine and compare values of  carcinoembryonic antigen (CEA) and cancer antigen (CA 15-3) in 50 bitches with mammary tumors...

Tumor Markers in Dogs with Mammary Gland Tumors

Published Online: Dec 14, 2023

Page range: 473 - 485

Accepted: Nov 17, 2023

DOI: https://doi.org/10.2478/acve-2023-0036

Keywords
dog, tumor markers, CEA, CA 15-3, mammary gland tumors

© 2023 Alexandra Valencakova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Tumor Markers in Dogs with Mammary Gland Tumors

Published Online: Dec 14, 2023

Page range: 473 - 485

Accepted: Nov 17, 2023

DOI: https://doi.org/10.2478/acve-2023-0036

Keywordsdog, tumor markers, CEA, CA 15-3, mammary gland tumors

© 2023 Alexandra Valencakova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
dog, tumor markers, CEA, CA 15-3, mammary gland tumors