<abstract xmlns="http://www.w3.org/1999/xhtml"><p>This report describes a case of canine hemotropic mycoplasmasosis by <italic>Candidatus</italic> Mycoplasma haematoparvum in a dog. A five-year-old splenectomized dog was referred to the Veterinary Teaching Hospital of the University of Sassari with clinical symptoms and laboratory findings compatible with immune-mediated hemolytic anemia. Epicellular bacteria were detected in the erythrocytes by microscopic examination of blood smears. PCR and sequencing were positive for <italic>Candidatus</italic> Mycoplasma haematoparvum. Treatment with doxycycline, prednisolone and blood transfusion was administered. Several studies have described the molecular prevalence of <italic>M. hemocanis</italic> and <italic>Candidatus</italic> M. haematoparvum, however there are few clinical reports, especially those describing <italic>Candidatus</italic> M. haematoparvum infection in dogs, for which only two cases have been reported. To the best of our knowledge this is the first case report of a symptomatic infection caused by <italic>Candidatus</italic> Mycoplasma haematoparvum in Italy. Hemoplasmosis should be considered as a potential cause of hemolytic anemia in dogs. Following treatment with doxycycline and prednisolone, the clinical signs improved without resolution of infection. This condition was the same at the three-year follow-up.</p></abstract>

This report describes a case of canine hemotropic mycoplasmasosis by Candidatus Mycoplasma haematoparvum in a dog. A five-year-old splenectomized dog was referred to the Veterinary Teaching Hospital of the University of Sassari with clinical symptoms and laboratory findings compatible with immune-mediated hemolytic anemia. Epicellular bacteria were detected in the erythrocytes by microscopic examination of blood smears. PCR and sequencing were positive for Candidatus Mycoplasma haematoparvum. Treatment with doxycycline, prednisolone and blood transfusion was administered. Several studies have described the molecular prevalence of M. hemocanis and Candidatus M. haematoparvum, however there are few clinical reports, especially those describing Candidatus M. haematoparvum infection in dogs, for which only two cases have been reported. To the best of our knowledge this is the first case report of a symptomatic infection caused by Candidatus Mycoplasma haematoparvum in Italy. Hemoplasmosis should be considered as a potential cause of hemolytic anemia in dogs. Following treatment with doxycycline and prednisolone, the clinical signs improved without resolution of infection. This condition was the same at the three-year follow-up.

Immune-Mediated Hemolytic Anemia Associated with <italic>Candidatus</italic> Mycoplasma Haematoparvum in a Splenectomized Dog in Italy

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Immune-Mediated Hemolytic Anemia Associated with  Mycoplasma Haematoparvum in a Splenectomized Dog in Italy

This report describes a case of canine hemotropic mycoplasmasosis by Candidatus Mycoplasma haematoparvum in a dog. A five-year-old splenectomized dog was...

Immune-Mediated Hemolytic Anemia Associated with Candidatus Mycoplasma Haematoparvum in a Splenectomized Dog in Italy

Published Online: Jun 08, 2020

Page range: 277 - 284

Received: Jul 05, 2019

Accepted: Dec 23, 2019

DOI: https://doi.org/10.2478/acve-2020-0020

Keywords
Mycoplasma haematoparvum, Immune-mediated hemolytic anemia, Polymerase chain reaction, Phylogenetic analysis

© 2020 Zobba Rosanna et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Immune-Mediated Hemolytic Anemia Associated with Candidatus Mycoplasma Haematoparvum in a Splenectomized Dog in Italy

Published Online: Jun 08, 2020

Page range: 277 - 284

Received: Jul 05, 2019

Accepted: Dec 23, 2019

DOI: https://doi.org/10.2478/acve-2020-0020

KeywordsMycoplasma haematoparvum, Immune-mediated hemolytic anemia, Polymerase chain reaction, Phylogenetic analysis

© 2020 Zobba Rosanna et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Mycoplasma haematoparvum, Immune-mediated hemolytic anemia, Polymerase chain reaction, Phylogenetic analysis