1. bookVolume 69 (2019): Issue 4 (December 2019)
Journal Details
License
Format
Journal
First Published
25 Mar 2014
Publication timeframe
4 times per year
Languages
English
access type Open Access

Influence of Selenium on the Morphology of Immune System Organs in Healthy Broilers

Published Online: 21 Dec 2019
Page range: 379 - 390
Received: 20 Nov 2019
Accepted: 02 Dec 2019
Journal Details
License
Format
Journal
First Published
25 Mar 2014
Publication timeframe
4 times per year
Languages
English

This study aimed to establish the effect of dietary supplementation in broiler chickens of organic and inorganic selenium on the weight and structure of the thymus, bursa of Fabricius and spleen. Three dietary regimes were studied in Flex and F15 Hubbard chickens: (i) control, (ii) diets containing 0.5 mg organic selenium/kg by selenized yeast, (iii) diets supplemented with 0.5 mg ionic selenium/kg (sodium selenite). The results showed that the feed additives did not affect the relative weight of the immune system organs, i.e. bursa of Fabricius, thymus and spleen. The organic selenium in the F15 resulted in thinning of the thymic cortex and partial depletion of the lymphoid cells. Moreover, both the organic and inorganic selenium supplementation resulted in depopulation of bursal medulla from lymphocytes in the F15 group. In contrast, in Flex chickens no significant differences in histological structure and morphometric values of lymphoid organs between chickens fed organic and inorganic selenium were found.

Keywords

1. Kidd MT: Nutritional modulation of immune function in broilers. Poult Sci 2004, 83:650-657.Search in Google Scholar

2. Payne RL, Southern LL: Comparison of inorganic and organic selenium sources for broilers. Poult Sci 2005, 84:898-902.Search in Google Scholar

3. Niu Z, Liu F, Yan Q, Li L: Effects of different levels of selenium on growth performance and immunocompetence of broilers under heat stress. Arch Anim Nutr 2009, 63:56-65.Search in Google Scholar

4. Habibian M, Ghazi S, Mehdi Moeini M, Abdolmohammadi A: Effects of dietary selenium and vitamin E on immune response and biological blood parameters of broilers reared under thermoneutral or heat stress conditions. Int J Biometeorol 2014, 58:741-752.Search in Google Scholar

5. Todorović M, Jovanović M, Jokić Ž, Hristov S, Davidović V: Alterations in liver and kidneys of chickens fed with high levels of sodium selenite or selenized yeast Acta Veterinaria-Beograd, 2004, 54(2-3):191-200.Search in Google Scholar

6. Biswas A, Mohan J, Sastry KVH: Effect of higher levels of dietary selenium on production performance and immune responses in growing Japanese quail. Br. Poult Sci 2006, 47:511-515.Search in Google Scholar

7. Franson JC, Hoffman DJ, Wells-Berlin A, Perry MC, Shearn-Bochsler V, Finley DL, Flint PL, Hollmen T: Effects of dietary selenium on tissue concentrations, pathology, oxidative stress, and immune function in common eiders (Somateria mollissima). J Toxicol Environ Health Part A 2007, 70:861-874.Search in Google Scholar

8. Chen K, Peng X, Fang J, Cui H, Zuo Z, Deng J, Chen Z, Geng Y, Lai W, Tang L, Yang Q: Effects of dietary selenium on histopathological changes and T cells of spleen in broilers exposed to aflatoxin B1. Int J Environ Res Pub Health 2014, 11:1904-1913.Search in Google Scholar

9. Ryu YC, Rhee MS, Lee KM, Kim BC: Effects of different levels of dietary supplemental selenium on performance, lipid oxidation, and color stability of broiler chicks. Poult Sci 2005, 84:809-815.Search in Google Scholar

10. Bjelica J, Jovanović I, Ilić V, Valčić O, Kirovski D, Gvozdić D, Milanović S: Effects of selenium and thyroid hormone deficiency on peritoneal macrophages adhesion and occurrence of natural IgM antibodies in juvenile rats. Acta Veterinaria-Beograd 2017, 67(3):340-355.Search in Google Scholar

11. Juszczyk P, Smolczyk A, Gil Z, Rymowicz W: Production of the Yarrowia lipolytica fodder yest enriched in selenoaminoacids and B12 vitamin. Inż Ap Chem 2015, 54:165-166.Search in Google Scholar

12. Hegazy SM, Adachi Y: Comparison of the effects of dietary selenium, zinc, and selenium and zinc supplementation on growth and immune response between chick groups that were inoculated with Salmonella and aflatoxin or Salmonella. Poult Sci 2000, 79:331-335.Search in Google Scholar

13. Cai SJ, Wu CX, Gong LM, Song T, Wu H, Zhang LY: Effects of nano-selenium on performance, meat quality, immune function, oxidation resistance, and tissue selenium content in broilers. Poult Sci 2012, 91:2532-2539.Search in Google Scholar

14. Swain BK, Johri TS, Majumdar S: Effect of supplementation of vitamin E, selenium and their different combinations on the performance and immune response of broilers. Br Poult Sci 2000, 41:287-292.Search in Google Scholar

15. Khan MZ, Akter SH, Islam MN, Karim MR, Islam MR, Kon Y: The effect of selenium and vitamin E on the lymphocytes and immunoglobulin-containing plasma cells in the lymphoid organ and mucosa-associated lymphatic tissues of broiler chickens. Anatom Histol Embryol 2008, 37:52-9.Search in Google Scholar

16. Peng X, Cui H, He Y, Cui W, Fang J, Zuo Z, Deng J, Pan K, Zhou Y, Lai W: Excess dietary sodium selenite alters apoptotic population and oxidative stress markers of spleens in broilers. Biol Tr Elem Res 2012, 145:47-51.Search in Google Scholar

17. Peng X, Cui Y, Cui W, Deng J, Cui H: The decrease of relative weight, lesions, and apoptosis of bursa of Fabricius induced by excess dietary selenium in chickens. Biol Tr Elem Res 2009, 131:33-42.Search in Google Scholar

Recommended articles from Trend MD

Plan your remote conference with Sciendo