<abstract xmlns="http://www.w3.org/1999/xhtml"><p> A mixture of galacto-oligosaccharides and non-prebiotic sugars was separated using a simulated moving bed unit equipped with eight packed-bed columns of a cation exchanger. In order to determine operating conditions using triangle theory, equilibrium adsorption isotherms of galactose, glucose, lactose, tri- and tetragalacto-oligosaccharide were measured. It was found that each column of the SMB unit had a maximum separation efficiency of more than 3000 theoretical plates. The achieved purity of galacto-oligosaccharides in the raffinate stream was 99.9 %, similarly 99.9 % of extract was formed by non-prebiotic sugars lactose, glucose and galactose. The productivities in the raffinate and extract, were 0.6 g/(L h) and 2.4 g/(L h), respectively.</p></abstract>

A mixture of galacto-oligosaccharides and non-prebiotic sugars was separated using a simulated moving bed unit equipped with eight packed-bed columns of a cation exchanger. In order to determine operating conditions using triangle theory, equilibrium adsorption isotherms of galactose, glucose, lactose, tri- and tetragalacto-oligosaccharide were measured. It was found that each column of the SMB unit had a maximum separation efficiency of more than 3000 theoretical plates. The achieved purity of galacto-oligosaccharides in the raffinate stream was 99.9 %, similarly 99.9 % of extract was formed by non-prebiotic sugars lactose, glucose and galactose. The productivities in the raffinate and extract, were 0.6 g/(L h) and 2.4 g/(L h), respectively.

Simulated moving bed chromatography separation of galacto-oligosaccharides

Department of Chemical and Biochemical Engineering, Institute of Chemical and Environmental Engineering, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, 812 37 Bratislava, Slovakia

Acta Chimica Slovaca

{"article-title":"Simulated moving bed chromatography separation of galacto-oligosaccharides"}

A mixture of galacto-oligosaccharides and non-prebiotic sugars was separated using a simulated moving bed unit equipped with eight packed-bed columns of a...

Simulated moving bed chromatography separation of galacto-oligosaccharides

Published Online: Nov 23, 2013

Page range: 206 - 210

DOI: https://doi.org/10.2478/acs-2013-0033

Keywords
simulated moving bed chromatography, galacto-oligosaccharides, adsorption isotherm

This content is open access.

Simulated moving bed chromatography separation of galacto-oligosaccharides

Published Online: Nov 23, 2013

Page range: 206 - 210

DOI: https://doi.org/10.2478/acs-2013-0033

Keywordssimulated moving bed chromatography, galacto-oligosaccharides, adsorption isotherm

This content is open access.

Keywords
simulated moving bed chromatography, galacto-oligosaccharides, adsorption isotherm