<abstract xmlns="http://www.w3.org/1999/xhtml"><p> The primary role of the biosensor is to specifically detect an analyte using biochemical reaction or interaction mediated by isolated biomolecules, organelles, whole cells or biomimetic receptors. In terms of construction and function, the biosensor consists of biorecognition element and transducer connected to suitable measurement device. Electrochemical biosensor is an electrode or microelectrode with the surface chemically modified by the biorecognition element. The main problem of analysis with the biosensors is the presence of low and high molecular weight substances in the sample that interfere at the detection of analyte. Due to deposition of surface active compounds the biosensor response may be diminished depending on time of interaction with sample. These effects can be eliminated by using anti-interference membranes. This review deals with preparation and utilization of membranes for the biocomponent immobilization and with outer-sphere protective membranes.</p></abstract>

The primary role of the biosensor is to specifically detect an analyte using biochemical reaction or interaction mediated by isolated biomolecules, organelles, whole cells or biomimetic receptors. In terms of construction and function, the biosensor consists of biorecognition element and transducer connected to suitable measurement device. Electrochemical biosensor is an electrode or microelectrode with the surface chemically modified by the biorecognition element. The main problem of analysis with the biosensors is the presence of low and high molecular weight substances in the sample that interfere at the detection of analyte. Due to deposition of surface active compounds the biosensor response may be diminished depending on time of interaction with sample. These effects can be eliminated by using anti-interference membranes. This review deals with preparation and utilization of membranes for the biocomponent immobilization and with outer-sphere protective membranes.

Protective membranes at electrochemical biosensors

Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Radlinského 9, SK-812 37 Bratislava, Slovak Republic

Acta Chimica Slovaca

{"article-title":"Protective membranes at electrochemical biosensors"}

The primary role of the biosensor is to specifically detect an analyte using biochemical reaction or interaction mediated by isolated biomolecules, organelles,...

Protective membranes at electrochemical biosensors

Published Online: May 22, 2013

Page range: 35 - 41

DOI: https://doi.org/10.2478/acs-2013-0007

Keywords
biosensor, interference, surface active compounds, protective membrane, chemically modified electrode

This content is open access.

Protective membranes at electrochemical biosensors

Published Online: May 22, 2013

Page range: 35 - 41

DOI: https://doi.org/10.2478/acs-2013-0007

Keywordsbiosensor, interference, surface active compounds, protective membrane, chemically modified electrode

This content is open access.

Keywords
biosensor, interference, surface active compounds, protective membrane, chemically modified electrode