Pharmacological Evaluation of the Effects of Phenylcarbamic Acid Derivatives on Cardiovascular Functions in Rats

1. M. Polakovicova and R. Cizmarikova, Molecular docking study on the binding mode of cardioselective phenoxyaminopropanol blocker into b-adrenergic receptor subtypes, Acta Fac. Pharm. Univ. Comenianae 59 (2012) 44-53.Search in Google Scholar

2. I. Malik, R. Govender, E. Sedlarova, J. Csollei, J. Jampilek, A. Coffey, J. O´Mahony and L. Stanzel, The in vitro investigation of ortho-/meta-/para alkoxyphenylcarbamic acid esters containing substitued N-phenylpiperazin-1-yl fragment against Mycobacterium tuberculosis H37Ra strain, Microbiol. Biotech. Food Sci. 3 (2014) 395-397.Search in Google Scholar

3. K. Bruchata and R. Cizmarikova, New derivatives of aryloxyaminopropanol-structure biological activity relationship, Farm. Obzor 79 (2010) 287-293.Search in Google Scholar

4. D. P. Jindal, M. S. Coumara, G. Brunib and P. Massarelli, Synthesis and b1-, b2-adrenergic receptor binding studies of 4-acylamino-substituted phenoxypropanolamine and 5-acylamino-substitut- ed naphthyloxypropanolamine derivatives, Arzneim-Forsch/Drug Res. 52 (2002) 654-663; https://doi.org/10.1055/s-0031-129994710.1055/s-0031-1299947Search in Google Scholar

5. V. Cecchetti, F. Schiaffella, O. Tabarrini and A. Fravolini, (1,4-Benzothiazinyloxy) alkoxylpiperazine derivatives as potential antihypertensive agents, Bioorg. Med. Chem. Lett. 10 (2000) 465-468.10.1016/S0960-894X(00)00016-0Search in Google Scholar

6. E. Racanska, I. Tumova and T. Foltanova, 2-, and 4-flurophenylpiperazine derivatives of alkoxyphenylcarbamic acid and their potential antidysrhytmic effect, Farm. Obzor 74 (2005) 247- 250.Search in Google Scholar

7. C. V. Ram, Beta-blockers in hypertension, Am. J. Cardiol. 106 ( 2010) 1 819-1825; https://doi.org/10.1016/j.amjcard.2010.08.02310.1016/j.amjcard.2010.08.02321126627Search in Google Scholar

8. W. R. Chen, X. M. Shi, T. S. Yang, L. C. Zhao and L. G. Gao, Protective effect of metoprolol on arrhythmia and heart rate variability in healthy people with 24 hours of sleep deprivation, J. Interv. Card. Electrophysiol. 36 (2013) 267-272; https://doi.org/10.1007/s10840-012-9728-810.1007/s10840-012-9728-823179915Search in Google Scholar

9. I. Malik, E. Sedlarova, J. Csöllei, E. Racanska, J. Cizmarik and P. Kurfürst, Synthesis, physicochemical properties and biological activity of 1-(4-fluorophenvl)-4-[3-(2-,3- and 4-alkyloxyphenylcarbamoyloxy)-2-hydroxypropyl] piperaziniumchlorides, Sci. Pharm. 72 (2004) 283-291; https://doi:10.3797/scipharm.aut-04-24Search in Google Scholar

10. I. Malik, E. Sedlarova, J. Cizmarik, F. Andriamainty and J. Csollei, Study of physicochemical properties of 4-alkoxy-phenylcarbamic acid derivatives with various substituted N-phenylpiperazin-1-yl moiety in the basic part of the molecule, Farm. Obzor 74 (2005) 211-215.Search in Google Scholar

11. E. Racanska, M. Maruniak, I. Tumova and E. Sedlarova, In vitro pharmacological evaluation of new phenylpiperazine derivatives of phenylcarbamic acid on their basic cardiovascular functions, Acta Facult. Pharm. Univ. Comenianae 57 (2010) 68-76.Search in Google Scholar

12. E. Kráľová, T. Mokráň, J. Murín and T. Stankovičová, Electrocardiography in two models of isoproterenol- induced left ventricular remodelling, Physiol. Res. 57 (Suppl. 2) (2008) S83-S89.10.33549/physiolres.93155618373388Search in Google Scholar

13. J. Kmecova and J. Klimas, Heart rate correction of the QT duration in rats, Eur. J. Pharmacol. 641 (2010) 187-192; https://doi.org/10.1016/j.ejphar.2010.05.03810.1016/j.ejphar.2010.05.03820553920Search in Google Scholar

14. M. Kobayashi, N. Machida, R. Tanaka and Y. Yamane, Effects of b-blocker on left ventricular remodeling in rats with volume overload cardiac failure, J. Vet. Med. Sci. 70 (2008) 1231-1237.10.1292/jvms.70.123119057143Search in Google Scholar

15. Ch. Baillard, P. Mansier, P. V. Ennezat, L. Mangin, C. Medigue, B. Swynghedaw and B.Chevalier, Converting enzyme inhibition normalizes QT interval in spontaneously hypertensive rats, Hypertension 36 (2000) 350-354; https://doi.org/10.1161/01.HYP.36.3.35010.1161/01.HYP.36.3.350Search in Google Scholar