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Acta Pharmaceutica
Volume 68 (2018): Issue 3 (September 2018)
Open Access
Pyrrolizine-5-carboxamides: Exploring the impact of various substituents on anti-inflammatory and anticancer activities
Ahmed M. Gouda
Ahmed M. Gouda
,
Ahmed H. Abdelazeem
Ahmed H. Abdelazeem
,
Ashraf N. Abdalla
Ashraf N. Abdalla
and
Muhammad Ahmed
Muhammad Ahmed
| Jul 04, 2018
Acta Pharmaceutica
Volume 68 (2018): Issue 3 (September 2018)
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Published Online:
Jul 04, 2018
Page range:
251 - 273
Accepted:
Mar 18, 2018
DOI:
https://doi.org/10.2478/acph-2018-0026
Keywords
pyrrolizine-5-carboxamide
,
anticancer
,
anti-inflammatory
,
COXs
,
apoptosis
,
substituent electronic effect
© 2018 Ahmed M. Gouda et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Ahmed M. Gouda
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University
Makkah, Saudi Arabia
Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University
Beni-Suef, Egypt
Ahmed H. Abdelazeem
Department of Medicinal Chemistry, Faculty of Pharmacy, Beni-Suef University
Beni-Suef, Egypt
Ashraf N. Abdalla
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Umm Al-Qura University
Makkah, Saudi Arabia
Department of Pharmacology Medicinal and Aromatic Plants Research Institute, National Center for Research,
Khartoum, Sudan
Muhammad Ahmed
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Umm Al-Qura University
Makkah, Saudi Arabia