[1. M. Grundmann and I. Kacirova, Significance of TDM, phenotyping and genotyping for the correct drug dosage, Cas. Lek. Ces. 149 (2010) 482-487.]Search in Google Scholar
[2. M. Grundmann, I. Kacirova and R. Urinovska, Therapeutic monitoring of psychoactive drugs - antidepressants: A review, Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub. (2013) in press; DOI: 10.5507/bp.2013.020.10.5507/bp.2013.02023549513]Search in Google Scholar
[3. I. Kacirova, M. Grundmann and R. Urinovska, General principles of therapeutic monitoring of psychoactive drugs, Klin. Farmakol. Farm. 26 (2012) 131-134.]Search in Google Scholar
[4. C. Hiemke and M. Shams, Phenotyping and genotyping of drug metabolism to guide pharmacotherapy in psychiatry, Curr. Drug Del. 10 (2013) 46-53.10.2174/156720181131001000822998042]Search in Google Scholar
[5. M. R. Muscatello, A. Bruno, G. Pandolfo, U. Micò, S. Settineri and R. Zoccali, Emerging treatments in the management of schizophrenia - focus on sertindole, Drug Des. Devel. Ther. 4 (2010) 187-201; DOI: 10.2147/DDDT.S6591.10.2147/DDDT.S6591293976320856845]Search in Google Scholar
[6. J. M. Kane and C. U. Correll, Past and present progress in the pharmacologic treatment of schizophrenia, J. Clin. Psychiatry 71 (2010) 1115-1124; DOI: 10.4088/JCP.10r06264yel10.4088/JCP.10r06264yel306524020923620]Search in Google Scholar
[7. J. W. Newcomer, Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review, CNS Drugs 19 (Suppl. 1) (2005) 1-93.]Search in Google Scholar
[8. N. Herrmann and K. L. Lanctot, Do atypical antipsychotics cause stroke?, CNS Drugs 19 (2005) 91-103.10.2165/00023210-200519020-0000115697324]Search in Google Scholar
[9. B. Luft and D. Taylor, A review of atypical antipsychotic drugs versus conventional medication in schizophrenia, Expert Opin. Pharmacother. 7 (2006) 1739-1748.10.1517/14656566.7.13.173916925501]Search in Google Scholar
[10. J. C. Huffman and J. E. Alpert, An approach to the psychopharmacologic care of patients: antidepressants, antipsychotics, anxiolytics, mood stabilizers, and natural remedies, Med. Clin. North Am. 94 (2010) 1141-1160; DOI: 10.1016/j.mcna.2010.08.009.10.1016/j.mcna.2010.08.00920951275]Search in Google Scholar
[11. C. Hiemke, A. Dragicevic, G. Gründer, S. Hättter, J. Sachse, I. Vernaleken and M. J. Müller, Therapeutic monitoring of new antipsychotic drugs, Ther. Drug Monit. 26 (2004) 156-160.10.1097/00007691-200404000-0001215228157]Search in Google Scholar
[12. L. Farde, A. L. Nordström, F. A. Wiesel, S. Pauli, C. Halldin and G. Sedvall, Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects, Arch. Gen. Psychiatry 49 (1992) 538-544.10.1001/archpsyc.1992.018200700320051352677]Search in Google Scholar
[13. S. Nyberg, A. L. Nordström, C. Halldin and L. Farde, Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man, Int. Clin. Psychopharmacol. 10 (Suppl. 3) (1995) 81-85.10.1097/00004850-199509000-00011]Search in Google Scholar
[14. P. J. Perry, Therapeutic drug monitoring of atypical antipsychotics. Is it of potential clinical value? CNS Drugs 13 (2000) 167-171.]Search in Google Scholar
[15. M. C. Mauri, L. S. Volonteri, A. Colasanti, A. Fiorentini, I. F. de Gaspari and S. R. Bareggi, Clinical pharmacokinetics of atypical antipsychotics. A critical review of the relationship between plasma concentrations and clinical response, Clin. Phamacokinet. 46 (2007) 359-388.10.2165/00003088-200746050-0000117465637]Search in Google Scholar
[16. L. Urichuk, T. I. Prior, S. Dursun and G. Baker, Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions, Curr. Drug Metab. 9 (2008) 410-418.]Search in Google Scholar
[17. E. Spina and J. de Leon, Metabolic drug interactions with newer antipsychotics: A comparative review, Basic Clin. Pharmacol. 100 (2007) 4-22.10.1111/j.1742-7843.2007.00017.x17214606]Search in Google Scholar
[18. R. C. Dorey, S. H. Preskorn and P. K. Widener, Results compared for tricyclic antidepressants as assayed by liquid chromatography and enzyme immunoassay, Clin. Chem. 34 (1988) 2348-2351.10.1093/clinchem/34.11.2348]Search in Google Scholar
[19. F. Saint-Marcoux, F. L. Sauvage and P. Marquet, Current role of LC-MS in therapeutic drug monitoring, Anal. Bioanal. Chem. 388 (2007) 1327-1349.10.1007/s00216-007-1320-117520242]Search in Google Scholar
[20. D. J. Brunswick, B. Needelman and J. Mendels, Specific radioimmunoassay of amitriptyline and nortriptyline, J. Clin. Pharmacol. 7 (1979) 343-348.10.1111/j.1365-2125.1979.tb00943.x1429641444353]Search in Google Scholar
[21. C. Fernandes, E. Hoeck, P. Sandra and F. M. Lancas, Determination of fluoxetine in plasma by gas chromatography-mass spectrometry using stir bar sorptive extraction, Anal. Chim. Acta 614 (2008) 201-207; DOI: 10.1016/j.aca.2008.03.036.10.1016/j.aca.2008.03.03618420052]Search in Google Scholar
[22. C. B. Eap, G. Bouchoux, M. Amey, N. Cochard, L. Savary and P. Baumann, Simultaneous determination of human plasma levels of citalopram, paroxetine, sertraline, and their metabolites by gas chromatography-mass spectrometry, J. Chromatogr. Sci. 36 (1998) 365-371.10.1093/chromsci/36.7.3659679303]Search in Google Scholar
[23. R. Urinovska, H. Brozmanova, P. Sistik, P. Silhan, I. Kacirova, K. Lemr and M. Grundmann, Liquid chromatography-tandem mass spectrometry method for determination of five antidepressants and four atypical antipsychotics and their main metabolites in human serum, J. Chromatogr. B. 907 (2012) 101-107; DOI: 10.1016/j.jchromb.2012.09.009.10.1016/j.jchromb.2012.09.00923026228]Search in Google Scholar
[24. H. Kirchherr and W. N. Kühn-Velten, Quantitative determination of forty-eight antidepressants and antipsychotics in human serum by HPLC tandem mass spectrometry: A multi-level, singlesample approach, J. Chromatogr. B. 843 (2006) 100-113. ]Search in Google Scholar
[25. K. K. Erickson-Ridout, D. Sun and P. Lazarus, Glucuronidation of the second-generation antipsychotic clozapine and its active metabolite N-desmethylclozapine. Potential importance of the UGT1A1 A(TA)7TAA and UGT1A4 L48V polymorphisms, Pharmacogen. Gen. 22 (2012) 561-576; DOI: 10.1097/FPC.0b013e328354026b.10.1097/FPC.0b013e328354026b627893522565219]Search in Google Scholar
[26. J. Leon, Glucuronidation enzymes, genes and psychiatry, Int. J. Neuropsychoph. 6 (2003) 57-72.10.1017/S146114570300324912899737]Search in Google Scholar
[27. H. L. Liston, J. S. Markowitz and C. L. de Vane, Drug glucuronidation in clinical psychopharmacology, J. Clin. Psychopharmacol. 21 (2001) 500-515.10.1097/00004714-200110000-0000811593076]Search in Google Scholar
[28. A. Y. Khan and S. H. Preskorn, Examining concentration-dependent toxicity of clozapine: role of therapeutic drug monitoring, J. Psychiatr. Pract. 11 (2005) 289-301.]Search in Google Scholar
[29. E. Spina, A. Avenoso, G. Facciolà, M.G. Scordo, M Ancione, A. G. Madia, A. Ventimiglia and E. Perucca, Relationship between plasma concentrations of clozapine and norclozapine and therapeutic response in patients with schizophrenia resistant to conventional neuroleptics, Psychopharmacology 148 (2000) 83-89.10.1007/s00213005002810663421]Search in Google Scholar
[30. P. J. Perry, D. D. Miller, S. V. Arndt and R. J. Cadoret, Clozapine and norclozapine plasma concentrations and clinical response of treatment-refractory schizophrenic patients, Am. J. Psychiatry 148 (1991) 231-235.10.1176/ajp.148.10.1406-b]Search in Google Scholar
[31. O. V. Olesen, K. Thomsen, P. N. Jensen, C. Wulff, N. A. Rasmussen, C. Refshammer, J. Sørensen, M. Bysted, J. Christensen and R. Rosenberg, Clozapine serum levels and side effects during steady state treatment of schizophrenic patients: a cross-sectional study, Psychopharmacology 117 (1995) 371-378.]Search in Google Scholar
[32. D. J. Freeman and L. K. Oyewumi, Will routine therapeutic drug monitoring have a place in clozapine therapy?, Clin. Pharmacokinet. 32 (1997) 93-100.10.2165/00003088-199732020-000019068925]Search in Google Scholar
[33. S. K. Lin, S. F. Su and C. Pan, Higher plasma drug concentration in clozapine-treated schizophrenic patients with side effects of obsessive/compulsive symptoms, Ther. Drug Monit. 28 (2006) 303-307.10.1097/01.ftd.0000211801.66569.8016778711]Search in Google Scholar
[34. M. van der Molen-Eijgenraam, J. T. Blanken-Meijs, M. Heeringa and A. C. van Grootheest, Delirium due to increase in clozapine level during an inflammatory reaction, Ned. Tijdschr. Geneeskd. 145 (2001) 427-430.]Search in Google Scholar
[35. J. A. Carrillo, A. G. Herraiz, S. I. Ramos and J. Benítez, Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients, J. Clin. Psychopharmacol. 18 (1998) 311-316.10.1097/00004714-199808000-000119690697]Search in Google Scholar
[36. V. Ozdemir, W. Kalow, P. Posner, E. J. Collins, J. L. Kennedy, B. K. Tang, L. J. Albers, C. Reist, R. Roy, W. Walkes and P. Afra, CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentration in patients with schizophrenia, J. Clin. Psychopharmacol. 21 (2001) 398-407.10.1097/00004714-200108000-0000711476124]Search in Google Scholar
[37. C. Hiemke, P. Baumann, N. Bergemann, A. Conca, O. Dietmaier, K. Egberts, M. Fric, M. Gerlach, C. Greiner, G. Gründer, E. Haen, U. Havemann-Reinecke, E. Jaquenoud Sirot, H. Kirchherr, G. Laux, U. C. Lutz , T. Messer, M. J. Müller, B. Pfuhlmann, B. Rambeck, P. Riederer, B. Schoppek, J. Stingl, M. Uhr, S. Ulrich, R. Waschgler and G. Zernig, AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011, Pharmacopsychiatry 44 (2011) 195-235; DOI: 10.1055/s-0031-1286287.10.1055/s-0031-128628721969060]Search in Google Scholar
[38. E. Ceskova, Would therapeutic drug monitoring improve adherence and efficaccy of treatment in schizophrenia?, Psychiat. Prax. 12 (2011) 166-178.]Search in Google Scholar
[39. K. Seto, J. Dumontet and M. H. Ensom, Risperidone in schizophrenia: is there a role for therapeutic drug monitoring?, Ther. Drug Monit. 33 (2011) 275-283; DOI: 10.1097/FTD.0b013e3182126d83.10.1097/FTD.0b013e3182126d8321436762]Search in Google Scholar
[40. E. Spina, A. Avenoso, G. Facciolà, M. Salemi, M. G. Scordo, M. Ancione, A. G. Madia and E. Perucca, Relationship between plasma risperidone and 9-hydroxyrisperidone concentrations and clinical response in patients with schizophrenia, Psychopharmacology 153 (2001) 238-243. 10.1007/s00213000057611205425]Search in Google Scholar
[41. J. K. Darby, D. J. Pasta, M. G. Wilson and J. Herbert, Long-term therapeutic drug monitoring of risperidone and olanzapine identifies altered steady-state pharmacokinetics: a clinical, twogroup, naturalistic study, Clin. Drug Invest. 28 (2008) 553-564.10.2165/00044011-200828090-0000218666802]Search in Google Scholar
[42. L. Citrome, Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability, Expert Opin. Drug Metab. Toxicol. 8 (2012) 873-888; DOI: 10.1517/17425255.2012.693160.10.1517/17425255.2012.69316022632481]Search in Google Scholar
[43. P. G. Janicak and E. A. Winans, Paliperidone ER: a review of the clinical trial data, Neuropsychiatr. Dis. Treat. 3 (2007) 869-897.10.2147/NDT.S1365]Search in Google Scholar
[44. K. K. Erickson-Ridout, J. Zhu and P. Lazarus, Olanzapine metabolism and the significance of UGT1A448V and UGT2B1067Y variants, Pharmacogenet. Genomics 21 (2011) 539-551; DOI: 10.1097/ FPC.0b013e328348c76b.10.1097/FPC.0b013e328348c76b628139421750471]Search in Google Scholar
[45. G. Gründer, C. Hiemke, M. Paulzen, T. Veselinovic and I. Vernaleken, Therapeutic plasma concentrations of antidepressants and antipsychotics: lessons from PET imaging, Pharmacopsychiatry 44 (2011) 236-248; DOI: 10.1055/s-0031-1286282.10.1055/s-0031-128628221959785]Search in Google Scholar
[46. O. Gefvert, M. Bergström, B. Långström, T. Lundberg, L. Lindström and R. Yates, Time course of central nervous dopamine-D2 and 5-HT2 receptor blockade and plasma drug concentration after discontinuation of quetiapine (Seroquet) in patients with schizophrenia, Psychopharmacology 135 (1998) 119-126.10.1007/s0021300504929497016]Search in Google Scholar
[47. M. C. Mauri, A. Fiorentini and L. S. Volonteri, Quetiapine in acute psychosis and personality disorders during hospitalization: assessment of a therapeutic range, Eur. Neuropsychopharmacol. 14 (2004) 283-284.]Search in Google Scholar
[48. J. R. Fabre, L. Arvanitis, J. Pultz, V. M. Jones, J. B. Malick and V. B. Slotnick, ICI 204.636. a novel atypical antipsychotic: early indication of safety and efficacy in patients with chronic and subchronic schizophrenia, Clin. Ther. 17 (1995) 366-378.]Search in Google Scholar
[49. J. G. Small, S. R. M. Hirsch, L. A. Arvanitis, B. G. Miller and C. G. Link, Quetiapine in patients with schizophrenia: a high- and low-dose double blind comparison with placebo, Arch. Gen. Psych. 54 (1997) 549-557.]Search in Google Scholar
[50. A. Sparshatt, D. Taylor, M. X. Patel and S. Kapur, Amisulpride - dose, plasma concentration, occupancy and response: implications for therapeutic drug monitoring, Acta Psychiatr. Scand. 120 (2009) 416-428; DOI: 10.1111/j.1600-0447.2009.01429.x.10.1111/j.1600-0447.2009.01429.x19573049]Search in Google Scholar
[51. M. J. Müller, B. Regenbogen, S. Härtter, F. X. Eich and C. Hiemke, Therapeutic drug monitoring for optimizing amisulpride therapy in patients with schizophrenia, J. Psychiatr. Res. 41 (2007) 673-679.10.1016/j.jpsychires.2005.10.00316324716]Search in Google Scholar
[52. F. Vogel, R. Gansmüller, T. Leiblein, O. Dietmaier, H. Wassmuth, G. Gründer and C. Hiemke, The use of ziprasidone in clinical practice: analysis of pharmacokinetic and pharmacodynamic aspects from data of a drug monitoring survey, Eur. Psychiatry 24 (2009) 143-148; DOI: 10.1016/j. eurpsy.2008.09.003.]Search in Google Scholar
[53. M. D. Cherma, M. Reis, S. Hägg, J. Ahlner and F. Bengtsson, Therapeutic drug monitoring of ziprasidone in a clinical treatment setting, Ther. Drug Monit. 30 (2008) 682-688; DOI: 10.1097/ FTD.0b013e31818ac8ba.10.1097/FTD.0b013e31818ac8ba18824954]Search in Google Scholar
[54. A. Sparshatt, D. Taylor, M. X. Patel and S. Kapur, A systematic review of aripiprazole-dose, plasma concentration, receptor occupancy, and response: implications for therapeutic drug monitoring, J. Clin. Psychiatry 71 (2010) 1447-1456; DOI: 10.4088/JCP.09r05060gre. 10.4088/JCP.09r05060gre20584524]Search in Google Scholar