<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Desmoplastic malignant melanoma is a rare variant of spindle cell melanoma commonly seen in older adults on sun-exposed areas. It accounts for 1–4 % of all cases of cutaneous melanoma. The common location of the desmoplastic melanoma is the head and neck region, whereasother sites are less common. A 45-year-old male presented with an proliferative growth on nose, after a trauma that was diagnosed as tumor. Histopathological examination with the help of wide panel of immunohistochemical methods and with emphasis on SOX10, was, after a broad diferential diagnosis concluded as a desmoplastic melanoma.</p>
</abstract>

Desmoplastic malignant melanoma is a rare variant of spindle cell melanoma commonly seen in older adults on sun-exposed areas. It accounts for 1–4 % of all cases of cutaneous melanoma. The common location of the desmoplastic melanoma is the head and neck region, whereasother sites are less common. A 45-year-old male presented with an proliferative growth on nose, after a trauma that was diagnosed as tumor. Histopathological examination with the help of wide panel of immunohistochemical methods and with emphasis on SOX10, was, after a broad diferential diagnosis concluded as a desmoplastic melanoma.

The Importance of Using SOX10 for Exact Diagnosis of Desmoplastic Melanoma

Department of Pathological Anatomy, Jessenius Faculty of Medicine in Martin

Comenius University in Bratislava and University Hospital Martin

Clinic of Dermatovenerology, Jessenius Faculty of Medicine in Martin

Department of Plastic Surgery, Jessenius Faculty of Medicine in Martin

Acta Medica Martiniana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"The Importance of Using SOX10 for Exact Diagnosis of Desmoplastic Melanoma"}

Desmoplastic malignant melanoma is a rare variant of spindle cell melanoma commonly seen in older adults on sun-exposed areas. It accounts for 1–4 % of all...

The Importance of Using SOX10 for Exact Diagnosis of Desmoplastic Melanoma

Published Online: Dec 05, 2019

Page range: 111 - 116

Received: Aug 23, 2019

Accepted: Oct 01, 2019

DOI: https://doi.org/10.2478/acm-2019-0015

Keywords
desmoplastic melanoma, spindle-cell variant, immunohistochemistry, SOX10, differential diagnosis

© 2019 K Adamicova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

The Importance of Using SOX10 for Exact Diagnosis of Desmoplastic Melanoma

Published Online: Dec 05, 2019

Page range: 111 - 116

Received: Aug 23, 2019

Accepted: Oct 01, 2019

DOI: https://doi.org/10.2478/acm-2019-0015

Keywordsdesmoplastic melanoma, spindle-cell variant, immunohistochemistry, SOX10, differential diagnosis

© 2019 K Adamicova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
desmoplastic melanoma, spindle-cell variant, immunohistochemistry, SOX10, differential diagnosis