<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>Inflammation may be associated with macular pigment optical density (MPOD) degradation.</p>
</sec>
<sec><h3>Objectives</h3>
<p>The relationship between inflammation and MPOD is evaluated using inflammatory biomarkers, including high sensitivity C-reactive protein (hsCRP), lipid level and ratio, waist circumference (WC), and body mass index (BMI).</p>
</sec>
<sec><h3>Method</h3>
<p>In this cross-sectional design, 62 hypertensive patients were recruited between January 6 and January 8, 2022, at a primary care unit. The MPOD was measured using the Macular pigment screener II. Blood tests for hsCRP, lipid profile, WC measurement, BMI calculation, and completing a questionnaire were conducted, and statistical analysis was done by using Microsoft Excel 2019 and Stata version 16.1. Spearman's rank correlation test was used to evaluate correlations. Multivariate analysis for adjusting confounders was done by logistic regression.</p>
</sec>
<sec><h3>Result</h3>
<p>There was a significant negative correlation between hsCRP >3 and MPOD (<italic>r</italic> = −0.26, <italic>P</italic> = 0.04).</p>
</sec>
<sec><h3>Conclusion</h3>
<p>Inflammation was linked to MPOD. Anti-inflammatory agents may be beneficial in preventing MPOD degradation.</p>
</sec>
</abstract>

Background
Inflammation may be associated with macular pigment optical density (MPOD) degradation.

Objectives
The relationship between inflammation and MPOD is evaluated using inflammatory biomarkers, including high sensitivity C-reactive protein (hsCRP), lipid level and ratio, waist circumference (WC), and body mass index (BMI).

Method
In this cross-sectional design, 62 hypertensive patients were recruited between January 6 and January 8, 2022, at a primary care unit. The MPOD was measured using the Macular pigment screener II. Blood tests for hsCRP, lipid profile, WC measurement, BMI calculation, and completing a questionnaire were conducted, and statistical analysis was done by using Microsoft Excel 2019 and Stata version 16.1. Spearman's rank correlation test was used to evaluate correlations. Multivariate analysis for adjusting confounders was done by logistic regression.

Result
There was a significant negative correlation between hsCRP >3 and MPOD (r = −0.26, P = 0.04).

Conclusion
Inflammation was linked to MPOD. Anti-inflammatory agents may be beneficial in preventing MPOD degradation.

The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study

School of Anti-Aging and Regenerative Medicine of Mae Fah Laung University

Asian Biomedicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
Inflammation may be associated with macular pigment optical density (MPOD) degradation.

Objectives
The relationship between inflammation and MPOD...

The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study

Article Category: Brief communication

Published Online: Oct 09, 2023

Page range: 144 - 149

DOI: https://doi.org/10.2478/abm-2023-0054

Keywords
hsCRP, hypertension, inflammatory biomarker, macular pigment optical density, macular pigment screener II

© 2023 Chunchuree Kongmeesuk Kaneko et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

The relationship between inflammatory biomarkers and macular pigment optical density in hypertensive patients: a cross-sectional study

Article Category: Brief communication

Published Online: Oct 09, 2023

Page range: 144 - 149

DOI: https://doi.org/10.2478/abm-2023-0054

KeywordshsCRP, hypertension, inflammatory biomarker, macular pigment optical density, macular pigment screener II

© 2023 Chunchuree Kongmeesuk Kaneko et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Keywords
hsCRP, hypertension, inflammatory biomarker, macular pigment optical density, macular pigment screener II