[1. Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns, GA. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature. 1990; 34:774-8.10.1038/343774a0]Search in Google Scholar
[2. Inoue K, Sugiyama H, Ogawa H, Nakagawa M, Yamagami T, Miwa H, et al. WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia. Blood. 1994; 84: 3071-9.10.1182/blood.V84.9.3071.3071]Search in Google Scholar
[3. Inoue K, Tamaki H, Ogawa H, Oka Y, Soma T, Tatekawa T, et al. Wilms’ tumor gene (WT1) competes with differentiation-inducing signal in hematopoietic progenitor cells. Blood. 1998; 91:2969-76.10.1182/blood.V91.8.2969.2969_2969_2976]Search in Google Scholar
[4. Chen Z. The possible role and application of WT1 in human leukemia. Int J Hematol. 2001; 73:39-46.10.1007/BF02981901]Open DOISearch in Google Scholar
[5. Algar E, Khromykh T, Smith S, Blackburn D, Bryson G, Smith P. A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines. Oncogene. 1996; 12:1005-14.]Search in Google Scholar
[6. Yamagami T, Sugiyama H, Inoue K, Ogawa H, Tatekawa T, Hirata M, et al. Growth inhibition of human leukemic cells by WT1 (Wilms’ tumor gene) antisense oligodeoxynucleotides: implications for the involvement of WT1 in leukemogenesis. Blood. 1996; 87:2878-84.10.1182/blood.V87.7.2878.bloodjournal8772878]Search in Google Scholar
[7. Smith SI, Down M, Boyd AW, Li CL. Expression of the Wilms’ tumor suppressor gene, WT1, reduces the tumorigenicity of the leukemic cell line M1 in C.B-17 scid/scid mice. Cancer Res. 2000; 60:808-14.]Search in Google Scholar
[8. Loeb DM, Evron E, Patel CB, Sharma PM, Niranjan B, Buluwela L, et al. Wilms’ tumor suppressor gene (WT1) is expressed in primary breast tumor despite tumor specific promoter methylation. Cancer Res. 2001; 61: 921-5.]Search in Google Scholar
[9. Navakanit R, Graidist P, Leeanansaksiri W, Dechsukum C. Growth inhibition of breast cancer cell line MCF-7 by siRNA silencing of Wilm tumor 1 gene. J Med Assoc Thai. 2007; 90:2416-21.]Search in Google Scholar
[10. Haber DA, Sohn RL, Buckler AJ, Pelletier J, Call KM, Housman DE. Alternative splicing and genomic structure of the Wilms’ tumor gene WT1. Proc Natl Acad Sci USA. 1991; 88:9618-22.10.1073/pnas.88.21.9618]Search in Google Scholar
[11. Yang L, Han Y, Saurez Saiz F, Minden MD. A tumor suppressor and oncogene: the WT1 story. Leukemia. 2007; 21:868-76.10.1038/sj.leu.2404624]Search in Google Scholar
[12. Wang ZY, Qiu QQ, Deuel TF. The Wilms’ tumor gene product WT1 activates or suppresses transcription through separate functional domains. J Biol Chem. 1993; 268:9172-5.10.1016/S0021-9258(18)98329-8]Search in Google Scholar
[13. Dechsukhum C, Ware JL, Ferreira-Gonalez A, Wilkinson DS, Garrett CT. Detection of novel truncated WT1 transcription in human neoplasia. Mol Diag. 2000; 5: 1-12.10.2165/00066982-200005020-00005]Search in Google Scholar
[14. Loeb DM. WT1 influences apoptosis through transcriptional regulation of Bcl-2 family members. Cell Cycle. 2006; 5:1249-53.10.4161/cc.5.12.280716760668]Search in Google Scholar
[15. Ito K, Oji Y, Tatsumi N, Shimizu S, Kanai Y, Nakazawa T, et al. Antiapoptotic function of 17AA(+)WT1 (Wilms’ tumor gene) isoforms on the intrinsic apoptosis pathway. Oncogene. 2006; 25:4217-29.10.1038/sj.onc.120945516518414]Search in Google Scholar
[16. Burwell EA, McCarty GP, Simpson LA, Thompson KA, Loeb DM. Isoforms of Wilms’ tumor suppressor gene (WT1) have distinct effects on mammary epithelial cells. Oncogene. 2007; 26:3423-30.10.1038/sj.onc.121012717160023]Search in Google Scholar
[17. Simpson LA, Burwell EA, Thompson KA, Shahnaz S, Chen AR, Loeb DM. The antiapoptotic gene A1/BEFL1 is a WT1 target gene that mediates granulocytic differentiation and resistance to chemotherapy. Blood. 2006; 107:4695-702.10.1182/blood-2005-10-4025189580516484585]Search in Google Scholar
[18. Lissy NA, Davis PK, Irwin M, Kaelin WG, Dowdy SF. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature. 2000; 407:642-5.10.1038/3503660811034214]Search in Google Scholar
[19. Drummond IA, Rupprecht HD, Rohwer-Nutter P, Lopez- Guisa JM, Madden SL, Rauscher FJ, et al. DNA recognition by splicing variant of the Wilms’ tumor suppressor, WT1. Mol Cell Biol. 1994; 14:3800-9.10.1128/MCB.14.6.3800]Search in Google Scholar
[20. Nichols KE, Re GG, Yan YX, Garvin AJ, Haber DA. WT1 induces expression of insulin-like growth factor 2 in Wilms’ tumor cells. Cancer Res. 1995; 55:4540-3.]Search in Google Scholar
[21. Caricasole A, Duarte A, Larsson SH, Hastie ND, Little M, Holmes G, et al. RNA binding by the Wilms’ tumor suppressor zinc finger proteins. Proc Natl Acad Sci USA. 1996; 93:7562-6.10.1073/pnas.93.15.7562387858755514]Open DOISearch in Google Scholar
[22. Hohenstein P, Hastie DN. The many facets of the Wilms’ tumour gene, WT1. Hum Mol Genet. 2006; 2: R196-201.10.1093/hmg/ddl19616987884]Open DOISearch in Google Scholar
[23. Jomgeow T, Oji Y, Tsuji N, Ikeda Y, Ito K, Tsuda A, et al. Wilms’ tumor gene WT1 17AA(-)/KTS(-) isoform induces morphological changes and promotes cell migration and invasion in vitro. Cancer Sci. 2006; 97: 259-70.10.1111/j.1349-7006.2006.00169.x16630117]Search in Google Scholar
[24. Oji Y, Ogawa H, Tamaki H, Oka Y, Tsuboi A, Kim EH, et al. Expression of the Wilm’s tumor gene WT1 in solid tumors and its involvement in tumor cell growth. Jpn J Cancer Res. 1999; 90:194-204.10.1111/j.1349-7006.1999.tb00733.x592605510189890]Search in Google Scholar
[25. Tatsumi N, Oji Y, Tsuji N, Tsuda A, Higashio M, Aoyagi S, et al. Wilms’ tumor gene WT1-shRNA as a potent apoptosis-inducing agent for solid tumors. Int J Oncol. 2008; 32:701-11.10.3892/ijo.32.3.701]Search in Google Scholar