<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Comparative cross sectional study was conducted on blood samples (n = 231) collected from children of 1 to 10 years of age in Punjab Pakistan through convenient sampling method. Indirect haemagglutination assay (IHA) was standardized and used for serodiagnosis and evaluation of humoral immunity against measles. Associated risk factors including age, gender, locale, and vaccination status were analyzed. Geometric mean titre (GMT) of vaccinated individuals was significantly higher (p &lt; 0.001) than that of non-vaccinated individuals showing that IHA titre of vaccinated individuals was a measure of humoral immune response; whereas, in case of non-vaccinated individuals an indicative of exposure to the measles infection.</p></abstract>

Comparative cross sectional study was conducted on blood samples (n = 231) collected from children of 1 to 10 years of age in Punjab Pakistan through convenient sampling method. Indirect haemagglutination assay (IHA) was standardized and used for serodiagnosis and evaluation of humoral immunity against measles. Associated risk factors including age, gender, locale, and vaccination status were analyzed. Geometric mean titre (GMT) of vaccinated individuals was significantly higher (p < 0.001) than that of non-vaccinated individuals showing that IHA titre of vaccinated individuals was a measure of humoral immune response; whereas, in case of non-vaccinated individuals an indicative of exposure to the measles infection.

Sero-epidemiology and Risk Factor Analysis of Measles Among Children in Pakistan

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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Comparative cross sectional study was conducted on blood samples (n = 231) collected from children of 1 to 10 years of age in Punjab Pakistan through...

Sero-epidemiology and Risk Factor Analysis of Measles Among Children in Pakistan

Article Category: short-communication

Published Online: Jun 30, 2018

Page range: 227 - 231

Received: Mar 21, 2017

Accepted: Jul 12, 2017

DOI: https://doi.org/10.21307/pjm-2018-025

Keywords
measles, sero-epidemiology, geometric mean titre, IHA

© 2018 Muhammad Hidayat Rasool et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Sero-epidemiology and Risk Factor Analysis of Measles Among Children in Pakistan

Article Category: short-communication

Published Online: Jun 30, 2018

Page range: 227 - 231

Received: Mar 21, 2017

Accepted: Jul 12, 2017

DOI: https://doi.org/10.21307/pjm-2018-025

Keywordsmeasles, sero-epidemiology, geometric mean titre, IHA

© 2018 Muhammad Hidayat Rasool et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
measles, sero-epidemiology, geometric mean titre, IHA