Interaction of agonists of a different subtype of the nAChR and carvacrol with GABA in Ascaris suum somatic muscle contractions

Abongwa, M., Martin, R. J. and Robertson, A. P. 2017. A brief review on the mode of action of antinematodal drugs. Acta Veterinaria (Beogr) 67:137–152. Abongwa M. Martin R. J. and Robertson A. P. 2017 . A brief review on the mode of action of antinematodal drugs . Acta Veterinaria (Beogr) 67 : 137 – 152 . 10.1515/acve-2017-0013579864729416226 Search in Google Scholar

Burrows, R. B. 1958. The anthelmintic effect of bephenium on Ancylostoma caninum. The Journal of Parasitology 44:607–610. Burrows R. B. 1958 . The anthelmintic effect of bephenium on Ancylostoma caninum . The Journal of Parasitology 44 : 607 – 610 . 10.2307/3274544 Search in Google Scholar

Courtot, E., Charvet, C. L., Beech, R. N., Harmache, A., Wolstenholme, A. J., Holden-Dye, L., O’Connor, V., Peineau, N., Woods, D. J. and Neveu, C. 2015. Functional characterization of a novel class of morantel-sensitive acetylcholine receptors in nematodes. PLoS Pathogens 11:e1005267. Courtot E. Charvet C. L. Beech R. N. Harmache A. Wolstenholme A. J. Holden-Dye L. O’Connor V. Peineau N. Woods D. J. and Neveu C. 2015 . Functional characterization of a novel class of morantel-sensitive acetylcholine receptors in nematodes . PLoS Pathogens 11 : e1005267 . 10.1371/journal.ppat.1005267466664526625142 Search in Google Scholar

Holden-Dye, L. and Walker, R. J. 2005-2018. Anthelmintic drugs and nematicides: studies in Caenorhabditis elegans. WormBook: The Online Review of C. elegans Biology [Internet]. Pasadena (CA): WormBook; 2005-2018. available at: https://www.ncbi.nlm.nih.gov/books/NBK116072/. Holden-Dye L and Walker, R. J 2005-2018 . Anthelmintic drugs and nematicides: studies in Caenorhabditis elegans. WormBook: The Online Review of C. elegans Biology [Internet] . Pasadena (CA): WormBook; 2005-2018. available at: https://www.ncbi.nlm.nih.gov/books/NBK116072/. Search in Google Scholar

Holden-Dye, L., Krogsgaard-Larsen, P., Nielsen, L. and Walker, R. J. 1989. GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABAA-type agonist recognition site. British Journal of Pharmacology 98:841–850. Holden-Dye L. Krogsgaard-Larsen P. Nielsen L. and Walker R. J. 1989 . GABA receptors on the somatic muscle cells of the parasitic nematode, Ascaris suum: stereoselectivity indicates similarity to a GABA_A-type agonist recognition site . British Journal of Pharmacology 98 : 841 – 850 . 10.1111/j.1476-5381.1989.tb14613.x18547912556203 Search in Google Scholar

Lei, J., Leser, M. and Enan, E. 2010. Nematicidal activity of two monoterpenoids and SER-2 tyramine receptor of Caenorhabditis elegans. Biochemical Pharmacology 79:1062–1071. Lei J. Leser M. and Enan E. 2010 . Nematicidal activity of two monoterpenoids and SER-2 tyramine receptor of Caenorhabditis elegans . Biochemical Pharmacology 79 : 1062 – 1071 . 10.1016/j.bcp.2009.11.00219896925 Search in Google Scholar

Marjanović, D. S., Zdravković, N., Milovanović, M., Trailović, J. N., Robertson, A. P., Todorović, Z. and Trailović, S. M. 2020. Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum. Veterinary Parasitology 278:109031. Marjanović D. S. Zdravković N. Milovanović M. Trailović J. N. Robertson A. P. Todorović Z. and Trailović S. M. 2020 . Carvacrol acts as a potent selective antagonist of different types of nicotinic acetylcholine receptors and enhances the effect of monepantel in the parasitic nematode Ascaris suum . Veterinary Parasitology 278 : 109031 . 10.1016/j.vetpar.2020.10903132032866 Search in Google Scholar

Martin, R. J. 1982. Electrophysiological effects of piperazine and diethylcarbamazine on Ascaris suum somatic muscle. British Journal of Pharmacology 77:255–265. Martin R. J. 1982 . Electrophysiological effects of piperazine and diethylcarbamazine on Ascaris suum somatic muscle . British Journal of Pharmacology 77 : 255 – 265 . 10.1111/j.1476-5381.1982.tb09294.x20445887139188 Search in Google Scholar

Martin, R. J. and Robertson, A. P. 2007. Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57. Parasitology 134:1093–1104. Martin R. J. and Robertson A. P. 2007 . Mode of action of levamisole and pyrantel, anthelmintic resistance, E153 and Q57 . Parasitology 134 : 1093 – 1104 . 10.1017/S003118200700002917608969 Search in Google Scholar

Martin, R. J., Clark, C. L., Trailovic, S. M. and Robertson, A. P. 2004. Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris. International Journal for Parasitology 34:1083–1090. Martin R. J. Clark C. L. Trailovic S. M. and Robertson A. P. 2004 . Oxantel is an N-type (methyridine and nicotine) agonist not an L-type (levamisole and pyrantel) agonist: classification of cholinergic anthelmintics in Ascaris . International Journal for Parasitology 34 : 1083 – 1090 . 10.1016/j.ijpara.2004.04.01415313135 Search in Google Scholar

Puttachary, S., Trailovic, S. M., Robertson, A. P., Thompson, D. P., Woods, D. J. and Martin, R. J. 2013. Derquantel and abamectin: effects and interactions on isolated tissues of Ascaris suum. Molecular and Biochemical Parasitology 188:79–86. Puttachary S. Trailovic S. M. Robertson A. P. Thompson D. P. Woods D. J. and Martin R. J. 2013 . Derquantel and abamectin: effects and interactions on isolated tissues of Ascaris suum . Molecular and Biochemical Parasitology 188 : 79 – 86 . 10.1016/j.molbiopara.2013.02.004386455523523993 Search in Google Scholar

Robertson, A. P., Bjørn, H. E. and Martin, R. J. 2000. Pyrantel resistance alters nematode nicotinic acetylcholine receptor single-channel properties. European Journal of Pharmacology 394:1–8. Robertson A. P. Bjørn H. E. and Martin R. J. 2000 . Pyrantel resistance alters nematode nicotinic acetylcholine receptor single-channel properties . European Journal of Pharmacology 394 : 1 – 8 . 10.1016/S0014-2999(00)00135-7 Search in Google Scholar

Robertson, A. P., Clark, C. L., Burns, T. A., Thompson, D. P., Geary, T. G., Trailovic, S. M. and Martin, R. J. 2002. Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle. The Journal of Pharmacology and Experimental Therapeutics 302:853–860. Robertson A. P. Clark C. L. Burns T. A. Thompson D. P. Geary T. G. Trailovic S. M. and Martin R. J. 2002 . Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle . The Journal of Pharmacology and Experimental Therapeutics 302 : 853 – 860 . 10.1124/jpet.102.034272 Search in Google Scholar

Tornøe, C., Bai, D., Holden-Dye, L., Abramson, S. N. and Sattelle, D. B. 1995. Actions of neurotoxins (bungarotoxins, neosurugatoxin, and lophotoxins) on insect and nematode nicotinic acetylcholine receptors. Toxicon 33:411–424. Tornøe C. Bai D. Holden-Dye L. Abramson S. N. and Sattelle D. B. 1995 . Actions of neurotoxins (bungarotoxins, neosurugatoxin, and lophotoxins) on insect and nematode nicotinic acetylcholine receptors . Toxicon 33 : 411 – 424 . 10.1016/0041-0101(94)00163-3 Search in Google Scholar

Trailovic, S. M. and Varagic, V. M. 2007. The effect of ivermectin on convulsions in rats produced by lidocaine and strychnine. Veterinary Research Communications 31:863–872. Trailovic S. M. and Varagic V. M. 2007 . The effect of ivermectin on convulsions in rats produced by lidocaine and strychnine . Veterinary Research Communications 31 : 863 – 872 . 10.1007/s11259-007-0050-317308985 Search in Google Scholar

Trailović, S. M., Zurovac, Z., Gruborović, S., Marjanović, D. S. and Nedeljković-Trailović, J. 2016. Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action. Journal of Helminthology 9:698–705. Trailović S. M. Zurovac Z. Gruborović S. Marjanović D. S. and Nedeljković-Trailović J. 2016 . Presynaptic and postsynaptic regulation of muscle contractions in the ascarid nematode Ascaris suum: a target for drug action . Journal of Helminthology 9 : 698 – 705 . 10.1017/S0022149X1500097826610818 Search in Google Scholar

Trailović, S. M., Marjanović, D. S., Nedeljković Trailović, J., Robertson, A. P. and Martin, R. J. 2015. Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action. Parasitology Research 114:3059–3068. Trailović S. M. Marjanović D. S. Nedeljković Trailović J. Robertson A. P. and Martin R. J. 2015 . Interaction of carvacrol with the Ascaris suum nicotinic acetylcholine receptors and gamma-aminobutyric acid receptors, potential mechanism of antinematodal action . Parasitology Research 114 : 3059 – 3068 . 10.1007/s00436-015-4508-x460727725944741 Search in Google Scholar

Wolstenholme, A. J. 2011. Ion channels and receptor as targets for the control of parasitic nematodes. International Journal for Parasitology: Drugs and Drug Resistance 1:2–13. Wolstenholme A. J. 2011 . Ion channels and receptor as targets for the control of parasitic nematodes . International Journal for Parasitology: Drugs and Drug Resistance 1 : 2 – 13 . Search in Google Scholar