<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Nonspecific binding of gamma globulin and complement, resulting in falsely positive indirect antiglobulin tests, has occurred with use of low-ionic strength saline solution (USS) reagents. These LISS-dependent antibodies have not been described in association with any particular disease state, nor do they have any apparent clinical significance. We present a LISS-dependent antibody with apparent autoanti-U specificity.</p></abstract>

Nonspecific binding of gamma globulin and complement, resulting in falsely positive indirect antiglobulin tests, has occurred with use of low-ionic strength saline solution (USS) reagents. These LISS-dependent antibodies have not been described in association with any particular disease state, nor do they have any apparent clinical significance. We present a LISS-dependent antibody with apparent autoanti-U specificity.

Liss-dependent autoantibody with apparent anti-U specificity

Immunohematology

{"article-title":"Liss-dependent autoantibody with apparent anti-U specificity"}

Nonspecific binding of gamma globulin and complement, resulting in falsely positive indirect antiglobulin tests, has occurred with use of low-ionic strength...

Liss-dependent autoantibody with apparent anti-U specificity

Published Online: Nov 17, 2020

Page range: 18 - 19

DOI: https://doi.org/10.21307/immunohematology-2019-781

© 1995 J. T. Chiofolo et al., published by Sciendo