<abstract xmlns="http://www.w3.org/1999/xhtml"><p>After the discovery (over 50 years ago) that the IAT could be applied to the detection of antibodies to blood group antigens, there was a rapid increase in the identification of alloantibodies that caused transfusion reactions or HDN. After Rh, antibodies in the Kell, Duffy, and Kidd blood group systems were the next in clinically significant antibodies to be revealed. Much of what has been learned about these blood groups since the journal <italic>Immunobematology</italic> issued its first edition has to do with the proteins, the genes, and the molecular basis for the antigens. What has not changed is that, after ABO and Rh, antibodies to antigens in these three systems are still the most clinically significant. They will form the basis of this review.</p></abstract>

After the discovery (over 50 years ago) that the IAT could be applied to the detection of antibodies to blood group antigens, there was a rapid increase in the identification of alloantibodies that caused transfusion reactions or HDN. After Rh, antibodies in the Kell, Duffy, and Kidd blood group systems were the next in clinically significant antibodies to be revealed. Much of what has been learned about these blood groups since the journal Immunobematology issued its first edition has to do with the proteins, the genes, and the molecular basis for the antigens. What has not changed is that, after ABO and Rh, antibodies to antigens in these three systems are still the most clinically significant. They will form the basis of this review.

Review: the Kell, Duffy, and Kidd blood group systems

Immunohematology

{"article-title":"Review: the Kell, Duffy, and Kidd blood group systems"}

After the discovery (over 50 years ago) that the IAT could be applied to the detection of antibodies to blood group antigens, there was a rapid increase in the...

Review: the Kell, Duffy, and Kidd blood group systems

Published Online: May 02, 2020

Page range: 37 - 46

DOI: https://doi.org/10.21307/immunohematology-2019-420

Keywords
blood group systems, Duffy, Kell, Kidd

© 2004 C.M. Westhoff et al., published by Sciendo

Review: the Kell, Duffy, and Kidd blood group systems

Published Online: May 02, 2020

Page range: 37 - 46

DOI: https://doi.org/10.21307/immunohematology-2019-420

Keywordsblood group systems, Duffy, Kell, Kidd

© 2004 C.M. Westhoff et al., published by Sciendo

Keywords
blood group systems, Duffy, Kell, Kidd