<abstract xmlns="http://www.w3.org/1999/xhtml"><p>In general, naturally occurring cold autoagglutinins react optimally at low temperatures. We describe a young child who experienced an acute hemolytic transfusion reaction by an unusual autoanti-I. The IgM autoanti-I was detected at 4°C (titer 256) and also reacted at 30°C. This case highlights the potential hazard of transfusing units of blood immediately upon removal from the blood refrigerator, especially into neonates and children of small stature. <italic><bold>Immunohematology</bold></italic><bold>2011;27:101–103.</bold></p></abstract>

In general, naturally occurring cold autoagglutinins react optimally at low temperatures. We describe a young child who experienced an acute hemolytic transfusion reaction by an unusual autoanti-I. The IgM autoanti-I was detected at 4°C (titer 256) and also reacted at 30°C. This case highlights the potential hazard of transfusing units of blood immediately upon removal from the blood refrigerator, especially into neonates and children of small stature. Immunohematology2011;27:101–103.

An unusual case of an acute hemolytic transfusion reaction caused by an autoanti-I

Immunohematology

In general, naturally occurring cold autoagglutinins react optimally at low temperatures. We describe a young child who experienced an acute hemolytic...

An unusual case of an acute hemolytic transfusion reaction caused by an autoanti-I

Article Category: Case Report

Published Online: Mar 11, 2020

Page range: 101 - 103

DOI: https://doi.org/10.21307/immunohematology-2019-182

© 2011 N. Win, et al., published by Sciendo