<abstract xmlns="http://www.w3.org/1999/xhtml">The Cartwright (Yt) blood group system consists of two antigens, Yta and Ytb, that result from point mutations in the acetylcholinesterase gene on chromosome 7q. Yta is a high-incidence antigen, whereas its antithetical antigen, Ytb, shows much lower incidence. Anti-Yta and anti-Ytb are relatively rare. Anti-Yta is more commonly found in individuals of Jewish descent. Cartwright antibodies are rarely clinically significant; however, cases of in vivo hemolysis have been reported, suggesting that clinical significance should be interpreted on a case-by-case basis. <italic><bold>Immunohematology</bold></italic><bold>2012;28:49–54.</bold></abstract>

The Cartwright (Yt) blood group system consists of two antigens, Yta and Ytb, that result from point mutations in the acetylcholinesterase gene on chromosome 7q. Yta is a high-incidence antigen, whereas its antithetical antigen, Ytb, shows much lower incidence. Anti-Yta and anti-Ytb are relatively rare. Anti-Yta is more commonly found in individuals of Jewish descent. Cartwright antibodies are rarely clinically significant; however, cases of in vivo hemolysis have been reported, suggesting that clinical significance should be interpreted on a case-by-case basis. Immunohematology2012;28:49–54.

Cartwright blood group system review

Immunohematology

{"article-title":"Cartwright blood group system review"}

The Cartwright (Yt) blood group system consists of two antigens, Yta and Ytb, that result from point mutations in the acetylcholinesterase gene on chromosome...

Cartwright blood group system review

Article Category: Review

Published Online: Dec 01, 2019

Page range: 49 - 54

DOI: https://doi.org/10.21307/immunohematology-2019-149

© 2012 M.R. George, published by Sciendo