This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Siegel JM. Sleep viewed as a state of adaptive inactivity. Nat Rev Neurosci. 2009;10(10):747-753.SiegelJM.Sleep viewed as a state of adaptive inactivity. Nat Rev Neurosci.2009;10(10):747-753.10.1038/nrn2697Search in Google Scholar
Ribeiro S. Sleep and plasticity. Pflugers Archiv Eur J Phy. 2012;463(1):111-120.RibeiroS.Sleep and plasticity. Pflugers Archiv Eur J Phy.2012;463(1):111-120.10.1007/s00424-011-1031-5Search in Google Scholar
Maquet P. The role of sleep in learning and memory. Science. 2001;294(5544):1048-1052.MaquetP.The role of sleep in learning and memory. Science.2001;294(5544):1048-1052.10.1126/science.1062856Search in Google Scholar
McGinty D, Szymusiak R. Keeping cool: a hypothesis about the mechanisms and functions of slow-wave sleep. Trends Neurosci. 1990;13(12):480-487.McGintyDSzymusiakR.Keeping cool: a hypothesis about the mechanisms and functions of slow-wave sleep. Trends Neurosci.1990;13(12):480-487.10.1016/0166-2236(90)90081-KSearch in Google Scholar
Adam K, Oswald I. Sleep is for tissue restoration. Clin Med (Lond). 1977;11(4):376-388.AdamKOswaldI.Sleep is for tissue restoration. Clin Med (Lond).1977;11(4):376-388.Search in Google Scholar
Bryant PA, Trinder J, Curtis N. Sick and tired: Does sleep have a vital role in the immune system? Nat Rev Immunol. 2004;4(6):457-467.BryantPATrinderJCurtisN.Sick and tired: Does sleep have a vital role in the immune system?Nat Rev Immunol.2004;4(6):457-467.10.1038/nri1369Search in Google Scholar
Berger RJ, Phillips NH. Energy conservation and sleep. Behav Brain Res. 1995;69(1-2):65-73.BergerRJPhillipsNH.Energy conservation and sleep. Behav Brain Res.1995;69(1-2):65-73.10.1016/0166-4328(95)00002-BSearch in Google Scholar
Inoue S, Honda K, Komoda Y. Sleep as neuronal detoxification and restitution. Behav Brain Res. 1995;69(1-2):91-96.InoueSHondaKKomodaY.Sleep as neuronal detoxification and restitution. Behav Brain Res.1995;69(1-2):91-96.10.1016/0166-4328(95)00014-KSearch in Google Scholar
United States Department of Labor. Americal time use survey 2015. Available from: http://www.bls.gov/tus/charts/.United States Department of Labor. Americal time use survey 2015. Available from: http://www.bls.gov/tus/charts/.Search in Google Scholar
Markwald RR, Melanson EL, Smith MR, Higgins J, Perreault L, Eckel RH, et al. Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci USA. 2013;110(14):5695-5700.MarkwaldRRMelansonELSmithMRHigginsJPerreaultLEckelRHet al.Impact of insufficient sleep on total daily energy expenditure, food intake, and weight gain. Proc Natl Acad Sci USA.2013;110(14):5695-5700.10.1073/pnas.1216951110Search in Google Scholar
Pilcher JJ, Ginter DR, Sadowsky B. Sleep quality versus sleep quantity: Relationships between sleep and measures of health, well-being and sleepiness in college students. J Psychosom Res. 1997;42(6):583-596.PilcherJJGinterDRSadowskyB.Sleep quality versus sleep quantity: Relationships between sleep and measures of health, well-being and sleepiness in college students. J Psychosom Res.1997;42(6):583-596.10.1016/S0022-3999(97)00004-4Search in Google Scholar
Lowrey PL, Takahashi JS. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu Rev Genom Hum G. 2004;5:407-441.LowreyPLTakahashiJS.Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu Rev Genom Hum G.2004;5:407-441.10.1146/annurev.genom.5.061903.175925Search in Google Scholar
Yamazaki S, Numano R, Abe M, Hida A, Takahashi RI, Ueda M, et al. Resetting central and peripheral circadian oscillators in transgenic rats. Science. 2000;288(5466):682-685.YamazakiSNumanoRAbeMHidaATakahashiRIUedaMet al.Resetting central and peripheral circadian oscillators in transgenic rats. Science.2000;288(5466):682-685.10.1126/science.288.5466.682Search in Google Scholar
Honma KI, Honma S, Hiroshige T. Response curve, free-running period, and activity time in circadian locomotor rhythm of rats. Jpn J Physiol. 1985;35(4):643-658.HonmaKIHonmaSHiroshigeT.Response curve, free-running period, and activity time in circadian locomotor rhythm of rats. Jpn J Physiol.1985;35(4):643-658.10.2170/jjphysiol.35.643Search in Google Scholar
Kohsaka A, Laposky AD, Ramsey KM, Estrada C, Joshu C, Kobayashi Y, et al. High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab. 2007;6(5):414-421.KohsakaALaposkyADRamseyKMEstradaCJoshuCKobayashiYet al.High-fat diet disrupts behavioral and molecular circadian rhythms in mice. Cell Metab.2007;6(5):414-421.10.1016/j.cmet.2007.09.006Search in Google Scholar
Campbell SS, Dawson D, Zulley J. When the human circadian system is caught napping: evidence for endogenous rhythms close to 24 hours. Sleep. 1993;16(7):638-640.CampbellSSDawsonDZulleyJ.When the human circadian system is caught napping: evidence for endogenous rhythms close to 24 hours. Sleep.1993;16(7):638-640.Search in Google Scholar
Czeisler CA, Duffy JF, Shanahan TL, Brown EN, Mitchell JF, Rimmer DW, et al. Stability, precision, and near-24-hour period of the human circadian pacemaker. Science. 1999;284(5423):2177-2181.CzeislerCADuffyJFShanahanTLBrownENMitchellJFRimmerDWet al.Stability, precision, and near-24-hour period of the human circadian pacemaker. Science.1999;284(5423):2177-2181.10.1126/science.284.5423.2177Search in Google Scholar
Middleton B, Arendt J, Stone BM. Complex effects of melatonin on human circadian rhythms in constant dim light. J Biol Rhythms. 1997;12(5):467-477.MiddletonBArendtJStoneBM.Complex effects of melatonin on human circadian rhythms in constant dim light. J Biol Rhythms.1997;12(5):467-477.10.1177/074873049701200508Search in Google Scholar
Dibner C, Schibler U. Circadian timing of metabolism in animal models and humans. J Intern Med. 2015;277(5):513-527.DibnerCSchiblerU.Circadian timing of metabolism in animal models and humans. J Intern Med.2015;277(5):513-527.10.1111/joim.12347Search in Google Scholar
Pittendrigh CS, Daan S. A functional analysis of circadian pacemakers in nocturnal rodents. IV. Entrainment: pacemaker as clock. J Comp Physiol. 1976;106(3):291-331.PittendrighCSDaanS.A functional analysis of circadian pacemakers in nocturnal rodents. IV. Entrainment: pacemaker as clock. J Comp Physiol.1976;106(3):291-331.10.1007/BF01417859Search in Google Scholar
Stepien JM, Kennaway DJ. Phase response relationships between light pulses and the melatonin rhythm in rats. J Biol Rhythms. 2001;16(3):234-242.StepienJMKennawayDJ.Phase response relationships between light pulses and the melatonin rhythm in rats. J Biol Rhythms.2001;16(3):234-242.10.1177/074873040101600306Search in Google Scholar
St Hilaire MA, Gooley JJ, Khalsa SBS, Kronauer RE, Czeisler CA, Lockley SW. Human phase response curve to a 1 h pulse of bright white light. J Physiol. 2012;590(13):3035-3045.St HilaireMAGooleyJJKhalsaSBSKronauerRECzeislerCALockleySW.Human phase response curve to a 1 h pulse of bright white light. J Physiol.2012;590(13):3035-3045.10.1113/jphysiol.2012.227892Search in Google Scholar
Czeisler CA, Kronauer RE, Allan JS, Duffy JF, Jewett ME, Brown EN, et al. Bright light induction of strong (type 0) resetting of the human circadian pacemaker. Science. 1989;244(4910):1328-1333.CzeislerCAKronauerREAllanJSDuffyJFJewettMEBrownENet al.Bright light induction of strong (type 0) resetting of the human circadian pacemaker. Science.1989;244(4910):1328-1333.10.1126/science.2734611Search in Google Scholar
Chang AM, Santhi N, St Hilaire M, Gronfier C, Bradstreet DS, Duffy JF, et al. Human responses to bright light of different durations. J Physiol. 2012;590(13):3103-3112.ChangAMSanthiNSt HilaireMGronfierCBradstreetDSDuffyJFet al.Human responses to bright light of different durations. J Physiol.2012;590(13):3103-3112.10.1113/jphysiol.2011.226555Search in Google Scholar
Zeitzer JM, Dijk DJ, Kronauer RE, Brown EN, Czeisler CA. Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression. J Physiol. 2000;526(3):695-702.ZeitzerJMDijkDJKronauerREBrownENCzeislerCA.Sensitivity of the human circadian pacemaker to nocturnal light: melatonin phase resetting and suppression. J Physiol.2000;526(3):695-702.10.1111/j.1469-7793.2000.00695.xSearch in Google Scholar
Wright HR, Lack LC, Kennaway DJ. Differential effects of light wavelength in phase advancing the melatonin rhythm. J Pineal Res. 2004;36(2):140-144.WrightHRLackLCKennawayDJ.Differential effects of light wavelength in phase advancing the melatonin rhythm. J Pineal Res.2004;36(2):140-144.10.1046/j.1600-079X.2003.00108.xSearch in Google Scholar
Guilding C, Hughes AT, Brown TM, Namvar S, Piggins HD. A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus. Mol Brain. 2009;2(1):28.GuildingCHughesATBrownTMNamvarSPigginsHD.A riot of rhythms: neuronal and glial circadian oscillators in the mediobasal hypothalamus. Mol Brain.2009;2(1):28.10.1186/1756-6606-2-28Search in Google Scholar
Sakamoto K, Nagase T, Fukui H, Horikawa K, Okada T, Tanaka H, et al. Multitissue circadian expression of rat period homolog (rPer2) mRNA is governed by the mammalian circadian clock, the suprachiasmatic nucleus in the brain. J Biol Chem. 1998;273(42):27039-27042.SakamotoKNagaseTFukuiHHorikawaKOkadaTTanakaHet al.Multitissue circadian expression of rat period homolog (rPer2) mRNA is governed by the mammalian circadian clock, the suprachiasmatic nucleus in the brain. J Biol Chem.1998;273(42):27039-27042.10.1074/jbc.273.42.27039Search in Google Scholar
Akhtar RA, Reddy AB, Maywood ES, Clayton JD, King VM, Smith AG, et al. Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol. 2002;12(7):540-550.AkhtarRAReddyABMaywoodESClaytonJDKingVMSmithAGet al.Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol.2002;12(7):540-550.10.1016/S0960-9822(02)00759-5Search in Google Scholar
Terazono H, Mutoh T, Yamaguchi S, Kobayashi M, Akiyama M, Udo R, et al. Adrenergic regulation of clock gene expression in mouse liver. Proc Natl Acad Sci USA. 2003;100(11):6795-6800.TerazonoHMutohTYamaguchiSKobayashiMAkiyamaMUdoRet al.Adrenergic regulation of clock gene expression in mouse liver. Proc Natl Acad Sci USA.2003;100(11):6795-6800.10.1073/pnas.0936797100Search in Google Scholar
Ueyama T, Krout KE, Van Nguyen X, Karpitskiy V, Kollert A, Mettenleiter TC, et al. Suprachiasmatic nucleus: a central autonomic clock. Nat Neurosci. 1999;2(12):1051-1053.UeyamaTKroutKEVan NguyenXKarpitskiyVKollertAMettenleiterTCet al.Suprachiasmatic nucleus: a central autonomic clock. Nat Neurosci.1999;2(12):1051-1053.10.1038/15973Search in Google Scholar
Vujovic N, Davidson AJ, Menaker M. Sympathetic input modulates, but does not determine, phase of peripheral circadian oscillators. Am J Physiol Regul Integr Comp Physiol. 2008;295(1):R355-R360.VujovicNDavidsonAJMenakerM.Sympathetic input modulates, but does not determine, phase of peripheral circadian oscillators. Am J Physiol Regul Integr Comp Physiol.2008;295(1):R355-R360.10.1152/ajpregu.00498.2007Search in Google Scholar
Cailotto C, La Fleur SE, Van Heijningen C, Wortel J, Kalsbeek A, Feenstra M, et al. The suprachiasmatic nucleus controls the daily variation of plasma glucose via the autonomic output to the liver: are the clock genes involved? European J Neurosci. 2005;22(10):2531-2540.CailottoCLa FleurSEVan HeijningenCWortelJKalsbeekAFeenstraMet al.The suprachiasmatic nucleus controls the daily variation of plasma glucose via the autonomic output to the liver: are the clock genes involved?European J Neurosci.2005;22(10):2531-2540.10.1111/j.1460-9568.2005.04439.xSearch in Google Scholar
Kalsbeek A, La Fleur S, Van Heijningen C, Buijs RM. Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver. J Neurosci. 2004;24(35):7604-7613.KalsbeekALa FleurSVan HeijningenCBuijsRM.Suprachiasmatic GABAergic inputs to the paraventricular nucleus control plasma glucose concentrations in the rat via sympathetic innervation of the liver. J Neurosci.2004;24(35):7604-7613.10.1523/JNEUROSCI.5328-03.2004Search in Google Scholar
Cailotto C, Lei J, van der Vliet J, van Heijningen C, van Eden CG, Kalsbeek A, et al. Effects of nocturnal light on (clock) gene expression in peripheral organs: a role for the autonomic innervation of the liver. PLoS ONE. 2009;4(5):e5650.CailottoCLeiJvan der VlietJvan HeijningenCvan EdenCGKalsbeekAet al.Effects of nocturnal light on (clock) gene expression in peripheral organs: a role for the autonomic innervation of the liver. PLoS ONE.2009;4(5):e5650.10.1371/journal.pone.0005650Search in Google Scholar
Bando H, Nishio T, Van Der Horst GTJ, Masubuchi S, Hisa Y, Okamura H. Vagal regulation of respiratory clocks in mice. J Neurosci. 2007;27(16):4359-4365.BandoHNishioTVan Der HorstGTJMasubuchiSHisaYOkamuraH.Vagal regulation of respiratory clocks in mice. J Neurosci.2007;27(16):4359-4365.10.1523/JNEUROSCI.4131-06.2007Search in Google Scholar
Buijs RM. Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway. Eur J Neurosci. 1999;11(5):1535-1544.BuijsRM.Anatomical and functional demonstration of a multisynaptic suprachiasmatic nucleus adrenal (cortex) pathway. Eur J Neurosci.1999;11(5):1535-1544.10.1046/j.1460-9568.1999.00575.xSearch in Google Scholar
Ishida A, Mutoh T, Ueyama T, Bando H, Masubuchi S, Nakahara D, et al. Light activates the adrenal gland: Timing of gene expression and glucocorticoid release. Cell Metabolism. 2005;2(5):297-307.IshidaAMutohTUeyamaTBandoHMasubuchiSNakaharaDet al.Light activates the adrenal gland: Timing of gene expression and glucocorticoid release. Cell Metabolism.2005;2(5):297-307.10.1016/j.cmet.2005.09.009Search in Google Scholar
Bartness TJ, Song CK, Demas GE. SCN efferents to peripheral tissues: implications for biological rhythms. J Biol Rhythms. 2001;16(3):196-204.BartnessTJSongCKDemasGE.SCN efferents to peripheral tissues: implications for biological rhythms. J Biol Rhythms.2001;16(3):196-204.10.1177/074873040101600302Search in Google Scholar
Alonso-Vale MIC, Andreotti S, Mukai PY, Borges-Silva CDN, Peres SB, Cipolla-Neto J, et al. Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes. J Pineal Res. 2008;45(4):422-429.Alonso-ValeMICAndreottiSMukaiPYBorges-SilvaCDNPeresSBCipolla-NetoJet al.Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes. J Pineal Res.2008;45(4):422-429.10.1111/j.1600-079X.2008.00610.xSearch in Google Scholar
Archer SN, Laing EE, Moller-Levet CS, Van Der Veen DR, Bucca G, Lazar AS, et al. Mistimed sleep disrupts circadian regulation of the human transcriptome. Proc Natl Acad Sci USA. 2014;111(6):E682-E691.ArcherSNLaingEEMoller-LevetCSVan Der VeenDRBuccaGLazarASet al.Mistimed sleep disrupts circadian regulation of the human transcriptome. Proc Natl Acad Sci USA.2014;111(6):E682-E691.10.1073/pnas.1316335111Search in Google Scholar
Vriend J, Reiter RJ. Melatonin feedback on clock genes: a theory involving the proteasome. J Pineal Res. 2015;58(1):1-11.VriendJReiterRJ.Melatonin feedback on clock genes: a theory involving the proteasome. J Pineal Res.2015;58(1):1-11.10.1111/jpi.12189Search in Google Scholar
Reddy AB, Maywood ES, Karp NA, King VM, Inoue Y, Gonzalez FJ, et al. Glucocorticoid signaling synchronizes the liver circadian transcriptome. Hepatology. 2007;45(6):1478-1488.ReddyABMaywoodESKarpNAKingVMInoueYGonzalezFJet al.Glucocorticoid signaling synchronizes the liver circadian transcriptome. Hepatology.2007;45(6):1478-1488.10.1002/hep.21571Search in Google Scholar
Yamamoto T, Nakahata Y, Tanaka M, Yoshida M, Soma H, Shinohara K, et al. Acute physical stress elevates mouse Period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive element. J Biol Chem. 2005;280(51):42036-42043.YamamotoTNakahataYTanakaMYoshidaMSomaHShinoharaKet al.Acute physical stress elevates mouse Period1 mRNA expression in mouse peripheral tissues via a glucocorticoid-responsive element. J Biol Chem.2005;280(51):42036-42043.10.1074/jbc.M509600200Search in Google Scholar
So AYL, Bernal TU, Pillsbury ML, Yamamoto KR, Feldman BJ. Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. Proc Natl Acad Sci USA. 2009;106(41):17582-17587.SoAYLBernalTUPillsburyMLYamamotoKRFeldmanBJ.Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. Proc Natl Acad Sci USA.2009;106(41):17582-17587.10.1073/pnas.0909733106Search in Google Scholar
Mohawk JA, Green CB, Takahashi JS. Central and peripheral circadian clocks in mammals. Annu Rev Neurosci. 2012;35:445-462.MohawkJAGreenCBTakahashiJS.Central and peripheral circadian clocks in mammals. Annu Rev Neurosci.2012;35:445-462.10.1146/annurev-neuro-060909-153128Search in Google Scholar
Rosenfeld P, Van Eekelen JAM, Levine S, De Kloet ER. Ontogeny of the Type 2 glucocorticoid receptor in discrete rat brain regions: an immunocytochemical study. Dev Brain Res. 1988;42(1):119-127.RosenfeldPVan EekelenJAMLevineSDe KloetER.Ontogeny of the Type 2 glucocorticoid receptor in discrete rat brain regions: an immunocytochemical study. Dev Brain Res.1988;42(1):119-127.10.1016/0165-3806(88)90207-6Search in Google Scholar
Su Y, Cailotto C, Foppen E, Jansen R, Zhang Z, Buijs R, et al. The role of feeding rhythm, adrenal hormones and neuronal inputs in synchronizing daily clock gene rhythms in the liver. Mol Cell Endocrinol. 2016;422:125-131.SuYCailottoCFoppenEJansenRZhangZBuijsRet al.The role of feeding rhythm, adrenal hormones and neuronal inputs in synchronizing daily clock gene rhythms in the liver. Mol Cell Endocrinol.2016;422:125-131.10.1016/j.mce.2015.12.011Search in Google Scholar
Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, Reichardt HM, et al. Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science. 2000;289(5488):2344-2347.BalsalobreABrownSAMarcacciLTroncheFKellendonkCReichardtHMet al.Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science.2000;289(5488):2344-2347.10.1126/science.289.5488.2344Search in Google Scholar
Cagnacci A, Krauchi K, Wirz-Justice A, Volpe A. Homeostatic versus circadian effects of melatonin on core body temperature in humans. J Biol Rhythms. 1997;12(6):509-517.CagnacciAKrauchiKWirz-JusticeAVolpeA.Homeostatic versus circadian effects of melatonin on core body temperature in humans. J Biol Rhythms.1997;12(6):509-517.10.1177/074873049701200604Search in Google Scholar
Brown SA, Zumbrunn G, Fleury-Olela F, Preitner N, Schibler U. Rhythms of mammalian body temperature can sustain peripheral circadian clocks. Curr Biol. 2002;12(18):1574-583.BrownSAZumbrunnGFleury-OlelaFPreitnerNSchiblerU.Rhythms of mammalian body temperature can sustain peripheral circadian clocks. Curr Biol.2002;12(18):1574-583.10.1016/S0960-9822(02)01145-4Search in Google Scholar
Reinke H, Saini C, Fleury-Olela F, Dibner C, Benjamin IJ, Schibler U. Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. Genes Dev. 2008;22(3):331-345.ReinkeHSainiCFleury-OlelaFDibnerCBenjaminIJSchiblerU.Differential display of DNA-binding proteins reveals heat-shock factor 1 as a circadian transcription factor. Genes Dev.2008;22(3):331-345.10.1101/gad.453808Search in Google Scholar
Buhr ED, Yoo SH, Takahashi JS. Temperature as a universal resetting cue for mammalian circadian oscillators. Science. 2010;330(6002):379-385.BuhrEDYooSHTakahashiJS.Temperature as a universal resetting cue for mammalian circadian oscillators. Science.2010;330(6002):379-385.10.1126/science.1195262Search in Google Scholar
Aschoff J. Exogenous and endogenous components in circadian rhythms. Cold Spring Harb Symp Quant Biol. 1960;25:11-28.AschoffJ.Exogenous and endogenous components in circadian rhythms. Cold Spring Harb Symp Quant Biol.1960;25:11-28.10.1101/SQB.1960.025.01.004Search in Google Scholar
Richter CP. Inborn nature of the rat’s 24-hour clock. J Comp Physiol Psych. 1971;75(1):1-4.RichterCP.Inborn nature of the rat’s 24-hour clock. J Comp Physiol Psych.1971;75(1):1-4.10.1037/h0030681Search in Google Scholar
Yamanaka Y, Honma S, Honma K-i. Scheduled exposures to a novel environment with a running-wheel differentially accelerate re-entrainment of mice peripheral clocks to new light-dark cycles. Genes Cells. 2008;13(5):497-507.YamanakaYHonmaSHonmaK-i.Scheduled exposures to a novel environment with a running-wheel differentially accelerate re-entrainment of mice peripheral clocks to new light-dark cycles. Genes Cells.2008;13(5):497-507.10.1111/j.1365-2443.2008.01183.xSearch in Google Scholar
Bjarnason GA, Jordan RCK, Wood PA, Li Q, Lincoln DW, Sothern RB, et al. Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol. 2001;158(5):1793-1801.BjarnasonGAJordanRCKWoodPALiQLincolnDWSothernRBet al.Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol.2001;158(5):1793-1801.10.1016/S0002-9440(10)64135-1Search in Google Scholar
Watanabe M, Hida A, Kitamura S, Enomoto M, Ohsawa Y, Katayose Y, et al. Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells. Biochem Biophys Res Commun. 2012;425(4):902-907.WatanabeMHidaAKitamuraSEnomotoMOhsawaYKatayoseYet al.Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells. Biochem Biophys Res Commun.2012;425(4):902-907.10.1016/j.bbrc.2012.08.008Search in Google Scholar
Janich P, Toufighi K, Solanas G, Luis NM, Minkwitz S, Serrano L, et al. Human epidermal stem cell function is regulated by circadian oscillations. Cell Stem Cell. 2013;13(6):745-753.JanichPToufighiKSolanasGLuisNMMinkwitzSSerranoLet al.Human epidermal stem cell function is regulated by circadian oscillations. Cell Stem Cell.2013;13(6):745-753.10.1016/j.stem.2013.09.004Search in Google Scholar
Schibler U, Ripperger J, Brown SA. Peripheral circadian oscillators in mammals: time and food. J Biol Rhythms. 2003;18(3):250-260.SchiblerURippergerJBrownSA.Peripheral circadian oscillators in mammals: time and food. J Biol Rhythms.2003;18(3):250-260.10.1177/0748730403018003007Search in Google Scholar
Akashi M, Soma H, Tsugitomi A, Yamashita S, Yamamoto T, Nishida E, et al. Noninvasive method for assessing the human circadian clock using hair follicle cells. Proc Natl Acad Sci USA. 2010;107(35):15643-15648.AkashiMSomaHTsugitomiAYamashitaSYamamotoTNishidaEet al.Noninvasive method for assessing the human circadian clock using hair follicle cells. Proc Natl Acad Sci USA.2010;107(35):15643-15648.10.1073/pnas.1003878107Search in Google Scholar
Okamoto A, Yamamoto T, Matsumura R, Node K, Akashi M. An out-of-lab trial: a case example for the effect of intensive exercise on rhythms of human clock gene expression. J Circadian Rhythms. 2013;11(1):10.OkamotoAYamamotoTMatsumuraRNodeKAkashiM.An out-of-lab trial: a case example for the effect of intensive exercise on rhythms of human clock gene expression. J Circadian Rhythms.2013;11(1):10.10.1186/1740-3391-11-10Search in Google Scholar
Baird AL, Coogan AN, Siddiqui A, Donev RM, Thome J. Adult attention-deficit hyperactivity disorder is associated with alterations in circadian rhythms at the behavioural, endocrine and molecular levels. Mol Psychiatry. 2012;17(10):988-995.BairdALCooganANSiddiquiADonevRMThomeJ.Adult attention-deficit hyperactivity disorder is associated with alterations in circadian rhythms at the behavioural, endocrine and molecular levels. Mol Psychiatry.2012;17(10):988-995.10.1038/mp.2011.149Search in Google Scholar
Cajochen C, Jud C, Munch M, Kobialka S, Wirz-Justice A, Albrecht U. Evening exposure to blue light stimulates the expression of the clock gene PER2 in humans. Eur J Neurosci. 2006;23(4):1082-1086.CajochenCJudCMunchMKobialkaSWirz-JusticeAAlbrechtU.Evening exposure to blue light stimulates the expression of the clock gene PER2 in humans. Eur J Neurosci.2006;23(4):1082-1086.10.1111/j.1460-9568.2006.04613.xSearch in Google Scholar
Novakova M, Sladek M, Sumova A. Human chronotype is determined in bodily cells under real-life conditions. Chronobiol Int. 2013;30(4):607-617.NovakovaMSladekMSumovaA.Human chronotype is determined in bodily cells under real-life conditions. Chronobiol Int.2013;30(4):607-617.10.3109/07420528.2012.754455Search in Google Scholar
Brown SA, Kunz D, Dumas A, Westermark PO, Vanselow K, Tilmann-Wahnschaffe A, et al. Molecular insights into human daily behavior. Proc Natl Acad Sci USA. 2008;105(5):1602-607.BrownSAKunzDDumasAWestermarkPOVanselowKTilmann-WahnschaffeAet al.Molecular insights into human daily behavior. Proc Natl Acad Sci USA.2008;105(5):1602-607.10.1073/pnas.0707772105Search in Google Scholar
Hasan S, Santhi N, Lazar AS, Slak A, Lo J, Von Schantz M, et al. Assessment of circadian rhythms in humans: Comparison of real-time fibroblast reporter imaging with plasma melatonin. FASEB J. 2012;26(6):2414-2423.HasanSSanthiNLazarASSlakALoJVon SchantzMet al.Assessment of circadian rhythms in humans: Comparison of real-time fibroblast reporter imaging with plasma melatonin. FASEB J.2012;26(6):2414-2423.10.1096/fj.11-201699Search in Google Scholar
Lippert J, Halfter H, Heidbreder A, Rohr D, Gess B, Boentert M, et al. Altered dynamics in the circadian oscillation of clock genes in dermal fibroblasts of patients suffering from idiopathic hypersomnia. PLoS ONE. 2014;9 (1):e85255.LippertJHalfterHHeidbrederARohrDGessBBoentertMet al.Altered dynamics in the circadian oscillation of clock genes in dermal fibroblasts of patients suffering from idiopathic hypersomnia. PLoS ONE.2014;9 (1):e85255.10.1371/journal.pone.0085255Search in Google Scholar
Sandu C, Dumas M, Malan A, Sambakhe D, Marteau C, Nizard C, et al. Human skin keratinocytes, melanocytes, and fibroblasts contain distinct circadian clock machineries. Cell Mol Life Sci. 2012;69(19):3329-3339.SanduCDumasMMalanASambakheDMarteauCNizardCet al.Human skin keratinocytes, melanocytes, and fibroblasts contain distinct circadian clock machineries. Cell Mol Life Sci.2012;69(19):3329-3339.10.1007/s00018-012-1026-1Search in Google Scholar
Burioka N, Koyanagi S, Endo M, Takata M, Fukuoka Y, Miyata M, et al. Clock gene dysfunction in patients with obstructive sleep apnoea syndrome. Eur Respir J. 2008;32(1):105-112.BuriokaNKoyanagiSEndoMTakataMFukuokaYMiyataMet al.Clock gene dysfunction in patients with obstructive sleep apnoea syndrome. Eur Respir J.2008;32(1):105-112.10.1183/09031936.00138207Search in Google Scholar
Lech K, Ackermann K, Revell VL, Lao O, Skene DJ, Kayser M. Dissecting daily and circadian expression rhythms of clock-controlled genes in human blood. J Biol Rhythms. 2016;31(1):68-81.LechKAckermannKRevellVLLaoOSkeneDJKayserM.Dissecting daily and circadian expression rhythms of clock-controlled genes in human blood. J Biol Rhythms.2016;31(1):68-81.10.1177/0748730415611761Search in Google Scholar
Moller-Levet CS, Archer SN, Bucca G, Laing EE, Slak A, Kabiljo R, et al. Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad Sci USA. 2013;110(12):E1132-E1141.Moller-LevetCSArcherSNBuccaGLaingEESlakAKabiljoRet al.Effects of insufficient sleep on circadian rhythmicity and expression amplitude of the human blood transcriptome. Proc Natl Acad Sci USA.2013;110(12):E1132-E1141.10.1073/pnas.1217154110Search in Google Scholar
Takimoto M, Hamada A, Tomoda A, Ohdo S, Ohmura T, Sakato H, et al. Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder. Am J Physiol Regul Integr Comp Physiol. 2005;289(5 58-5):R1273-R1279.TakimotoMHamadaATomodaAOhdoSOhmuraTSakatoHet al.Daily expression of clock genes in whole blood cells in healthy subjects and a patient with circadian rhythm sleep disorder. Am J Physiol Regul Integr Comp Physiol.2005;289(5 58-5):R1273-R1279.10.1152/ajpregu.00126.2005Search in Google Scholar
Zhu Y, Fu A, Hoffman AE, Figueiro MG, Carskadon MA, Sharkey KM, et al. Advanced sleep schedules affect circadian gene expression in young adults with delayed sleep schedules. Sleep Med. 2013;14(5):449-455.ZhuYFuAHoffmanAEFigueiroMGCarskadonMASharkeyKMet al.Advanced sleep schedules affect circadian gene expression in young adults with delayed sleep schedules. Sleep Med.2013;14(5):449-455.10.1016/j.sleep.2012.12.006Search in Google Scholar
Pivovarova O, Jurchott K, Rudovich N, Hornemann S, Ye L, Mockel S, et al. Changes of dietary fat and carbohydrate content alter central and peripheral clock in humans. J Clin Endocrinol Metab. 2015;100(6):2291-2302.PivovarovaOJurchottKRudovichNHornemannSYeLMockelSet al.Changes of dietary fat and carbohydrate content alter central and peripheral clock in humans. J Clin Endocrinol Metab.2015;100(6):2291-2302.10.1210/jc.2014-3868Search in Google Scholar
Boivin DB, James FO, Wu A, Cho-Park PF, Xiong H, Sun ZS. Circadian clock genes oscillate in human peripheral blood mononuclear cells. Blood. 2003;102(12):4143-4145.BoivinDBJamesFOWuACho-ParkPFXiongHSunZS.Circadian clock genes oscillate in human peripheral blood mononuclear cells. Blood.2003;102(12):4143-4145.10.1182/blood-2003-03-0779Search in Google Scholar
Cuesta M, Cermakian N, Boivin DB. Glucocorticoids entrain molecular clock components in human peripheral cells. FASEB J. 2015;29(4):1360-1370.CuestaMCermakianNBoivinDB.Glucocorticoids entrain molecular clock components in human peripheral cells. FASEB J.2015;29(4):1360-1370.10.1096/fj.14-265686Search in Google Scholar
Ebisawa T, Numazawa K, Shimada H, Izutsu H, Sasaki T, Kato N, et al. Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood. Neurosci Res. 2010;66(2):223-227.EbisawaTNumazawaKShimadaHIzutsuHSasakiTKatoNet al.Self-sustained circadian rhythm in cultured human mononuclear cells isolated from peripheral blood. Neurosci Res.2010;66(2):223-227.10.1016/j.neures.2009.10.007Search in Google Scholar
Huang MC, Ho CW, Chen CH, Liu SC, Chen CC, Leu SJ. Reduced expression of circadian clock genes in male alcoholic patients. Alcohol Clin Exp Res. 2010;34(11):1899-1904.HuangMCHoCWChenCHLiuSCChenCCLeuSJ.Reduced expression of circadian clock genes in male alcoholic patients. Alcohol Clin Exp Res.2010;34(11):1899-1904.10.1111/j.1530-0277.2010.01278.xSearch in Google Scholar
James FO, Boivin DB, Charbonneau S, Belanger V, Cermakian N. Expression of clock genes in human peripheral blood mononuclear cells throughout the sleep/wake and circadian cycles. Chronobiol Int. 2007;24(6):1009-1034.JamesFOBoivinDBCharbonneauSBelangerVCermakianN.Expression of clock genes in human peripheral blood mononuclear cells throughout the sleep/wake and circadian cycles. Chronobiol Int.2007;24(6):1009-1034.10.1080/07420520701800736Search in Google Scholar
Kavcic P, Rojc B, Dolenc-Groselj L, Claustrat B, Fujs K, Poljak M. The impact of sleep deprivation and nighttime light exposure on clock gene expression in humans. Croat Med J. 2011;52(5):594-603.KavcicPRojcBDolenc-GroseljLClaustratBFujsKPoljakM.The impact of sleep deprivation and nighttime light exposure on clock gene expression in humans. Croat Med J.2011;52(5):594-603.10.3325/cmj.2011.52.594Search in Google Scholar
Kusanagi H, Hida A, Satoh K, Echizenya M, Shimizu T, Pendergast JS, et al. Expression profiles of 10 circadian clock genes in human peripheral blood mononuclear cells. Neurosci Res. 2008;61(2):136-142.KusanagiHHidaASatohKEchizenyaMShimizuTPendergastJSet al.Expression profiles of 10 circadian clock genes in human peripheral blood mononuclear cells. Neurosci Res.2008;61(2):136-142.10.1016/j.neures.2008.01.012Search in Google Scholar
Kusanagi H, Mishima K, Satoh K, Echizenya M, Katoh T, Shimizu T. Similar profiles in human period1 gene expression in peripheral mononuclear and polymorphonuclear cells. Neurosci Lett. 2004;365(2):124-127.KusanagiHMishimaKSatohKEchizenyaMKatohTShimizuT.Similar profiles in human period1 gene expression in peripheral mononuclear and polymorphonuclear cells. Neurosci Lett.2004;365(2):124-127.10.1016/j.neulet.2004.04.065Search in Google Scholar
Teboul M, Barrat-Petit MA, Li XM, Claustrat B, Formento JL, Delaunay F, et al. Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells. J Mol Med. 2005;83(9):693-699.TeboulMBarrat-PetitMALiXMClaustratBFormentoJLDelaunayFet al.Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells. J Mol Med.2005;83(9):693-699.10.1007/s00109-005-0697-6Search in Google Scholar
Yang MY, Yang WC, Lin PM, Hsu JF, Hsiao HH, Liu YC, et al. Altered expression of circadian clock genes in human chronic myeloid leukemia. J Biol Rhythms. 2011;26(2):136-148.YangMYYangWCLinPMHsuJFHsiaoHHLiuYCet al.Altered expression of circadian clock genes in human chronic myeloid leukemia. J Biol Rhythms.2011;26(2):136-148.10.1177/0748730410395527Search in Google Scholar
Ackermann K, Plomp R, Lao O, Middleton B, Revell VL, Skene DJ, et al. Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans. Chronobiol Int. 2013;30(7):901-909.AckermannKPlompRLaoOMiddletonBRevellVLSkeneDJet al.Effect of sleep deprivation on rhythms of clock gene expression and melatonin in humans. Chronobiol Int.2013;30(7):901-909.10.3109/07420528.2013.784773Search in Google Scholar
Ackermann K, Sletten TL, Revell VL, Archer SN, Skene DJ. Blue-Light phase shifts PER3 gene expression in human leukocytes. Chronobiol Int. 2009;26(4):769-779.AckermannKSlettenTLRevellVLArcherSNSkeneDJ.Blue-Light phase shifts PER3 gene expression in human leukocytes. Chronobiol Int.2009;26(4):769-779.10.1080/07420520902929045Search in Google Scholar
Archer SN, Viola AU, Kyriakopoulou V, Von Schantz M, Dijk DJ. Inter-individual differences in habitual sleep timing and entrained phase of endogenous circadian rhythms of BMAL1, PER2 and PER3 mRNA in human leukocytes. Sleep. 2008;31(5):608-617.ArcherSNViolaAUKyriakopoulouVVon SchantzMDijkDJ.Inter-individual differences in habitual sleep timing and entrained phase of endogenous circadian rhythms of BMAL1, PER2 and PER3 mRNA in human leukocytes. Sleep.2008;31(5):608-617.10.1093/sleep/31.5.608Search in Google Scholar
Cai Y, Liu S, Sothern RB, Xu S, Chan P. Expression of clock genes Per1 and Bmal1 in total leukocytes in health and Parkinson’s disease. Eur J Neurol. 2010;17(4):550-554.CaiYLiuSSothernRBXuSChanP.Expression of clock genes Per1 and Bmal1 in total leukocytes in health and Parkinson’s disease. Eur J Neurol.2010;17(4):550-554.10.1111/j.1468-1331.2009.02848.xSearch in Google Scholar
Haimovich B, Calvano J, Haimovich AD, Calvano SE, Coyle SM, Lowry SF. In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes. Crit Care Med. 2010;38(3):751-758.HaimovichBCalvanoJHaimovichADCalvanoSECoyleSMLowrySF.In vivo endotoxin synchronizes and suppresses clock gene expression in human peripheral blood leukocytes. Crit Care Med.2010;38(3):751-758.10.1097/CCM.0b013e3181cd131cSearch in Google Scholar
Reszka E, Peplonska B, Wieczorek E, Sobala W, Bukowska A, Gromadzinska J, et al. Circadian gene expression in peripheral blood leukocytes of rotating night shift nurses. Scand J Work, Environ Health. 2013;39(2):187-194.ReszkaEPeplonskaBWieczorekESobalaWBukowskaAGromadzinskaJet al.Circadian gene expression in peripheral blood leukocytes of rotating night shift nurses. Scand J Work, Environ Health.2013;39(2):187-194.10.5271/sjweh.3303Search in Google Scholar
Bracci M, Manzella N, Copertaro A, Staffolani S, Barbaresi IM, Strafella E, et al. Rotating-shift nurses after a day off: peripheral clock gene expression, urinary melatonin, and serum 17-beta-estradiol levels. Scand J Work Environ Health. 2014;40(3):295-304.BracciMManzellaNCopertaroAStaffolaniSBarbaresiIMStrafellaEet al.Rotating-shift nurses after a day off: peripheral clock gene expression, urinary melatonin, and serum 17-beta-estradiol levels. Scand J Work Environ Health.2014;40(3):295-304.10.5271/sjweh.3414Search in Google Scholar
Baumann A, Gonnenwein S, Bischoff SC, Sherman H, Chapnik N, Froy O, et al. The circadian clock is functional in eosinophils and mast cells. Immunology. 2013;140(4):465-474.BaumannAGonnenweinSBischoffSCShermanHChapnikNFroyOet al.The circadian clock is functional in eosinophils and mast cells. Immunology.2013;140(4):465-474.10.1111/imm.12157Search in Google Scholar
Bollinger T, Leutz A, Leliavski A, Skrum L, Kovac J, Bonacina L, et al. Circadian clocks in mouse and human CD4+ T cells. PLoS ONE. 2011;6(12):e29801.BollingerTLeutzALeliavskiASkrumLKovacJBonacinaLet al.Circadian clocks in mouse and human CD4+ T cells. PLoS ONE.2011;6(12):e29801.10.1371/journal.pone.0029801Search in Google Scholar
Leibetseder V, Humpeler S, Svoboda M, Schmid D, Thalhammer T, Zuckermann A, et al. Clock genes display rhythmic expression in human hearts. Chronobiol Int. 2009;26(4):621-636.LeibetsederVHumpelerSSvobodaMSchmidDThalhammerTZuckermannAet al.Clock genes display rhythmic expression in human hearts. Chronobiol Int.2009;26(4):621-636.10.1080/07420520902924939Search in Google Scholar
Saini C, Petrenko V, Pulimeno P, Giovannoni L, Berney T, Hebrok M, et al. A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells. Diabetes Obes Metab. 2016;18(4):355-365.SainiCPetrenkoVPulimenoPGiovannoniLBerneyTHebrokMet al.A functional circadian clock is required for proper insulin secretion by human pancreatic islet cells. Diabetes Obes Metab.2016;18(4):355-365.10.1111/dom.12616Search in Google Scholar
Gomez-Abellan P, Diez-Noguera A, Madrid JA, Lujan JA, Ordovas JM, Garaulet M. Glucocorticoids affect 24 h clock genes expression in human adipose tissue explant cultures. PLoS ONE. 2012;7(12):e50435.Gomez-AbellanPDiez-NogueraAMadridJALujanJAOrdovasJMGarauletM.Glucocorticoids affect 24 h clock genes expression in human adipose tissue explant cultures. PLoS ONE.2012;7(12):e50435.10.1371/journal.pone.0050435Search in Google Scholar
Gomez-Abellan P, Hernandez-Morante JJ, Lujan JA, Madrid JA, Garaulet M. Clock genes are implicated in the human metabolic syndrome. Int J Obes. 2008;32(1):121-128.Gomez-AbellanPHernandez-MoranteJJLujanJAMadridJAGarauletM.Clock genes are implicated in the human metabolic syndrome. Int J Obes.2008;32(1):121-128.10.1038/sj.ijo.0803689Search in Google Scholar
Tsinkalovsky O, Smaaland R, Rosenlund B, Sothern RB, Hirt A, Steine S, et al. Circadian variations in clock gene expression of human bone marrow CD34+ cells. J Biol Rhythms. 2007;22(2):140-150.TsinkalovskyOSmaalandRRosenlundBSothernRBHirtASteineSet al.Circadian variations in clock gene expression of human bone marrow CD34+ cells. J Biol Rhythms.2007;22(2):140-150.10.1177/0748730406299078Search in Google Scholar
Scheer FAJL, Buijs RM. Light affects morning salivary cortisol in humans. J Clin Endocrinol Metab. 1999;84(9):3395-3398.ScheerFAJLBuijsRM.Light affects morning salivary cortisol in humans. J Clin Endocrinol Metab.1999;84(9):3395-3398.10.1210/jcem.84.9.6102Search in Google Scholar
Leproult R, Colecchia EF, L’Hermite-Baleriaux M, Van Cauter E. Transition from dim to bright light in the morning induces an immediate elevation of cortisol levels. J Clin Endocrinol Metab. 2001;86(1):151-157.LeproultRColecchiaEFL’Hermite-BaleriauxMVan CauterE.Transition from dim to bright light in the morning induces an immediate elevation of cortisol levels. J Clin Endocrinol Metab.2001;86(1):151-157.10.1210/jc.86.1.151Search in Google Scholar
Qian J, Block GD, Colwell CS, Matveyenko AV. Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats. Diabetes. 2013;62(10):3469-3478.QianJBlockGDColwellCSMatveyenkoAV.Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats. Diabetes.2013;62(10):3469-3478.10.2337/db12-1543Search in Google Scholar
Kiessling S, Eichele G, Oster H. Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag. J Clin Invest. 2010;120(7):2600-2609.KiesslingSEicheleGOsterH.Adrenal glucocorticoids have a key role in circadian resynchronization in a mouse model of jet lag. J Clin Invest.2010;120(7):2600-2609.10.1172/JCI41192Search in Google Scholar
Yamanaka Y, Honma S, Honma K-i. Mistimed wheel running interferes with re-entrainment of circadian Per1 rhythms in the mouse skeletal muscle and lung. Genes Cells. 2016;21(3):264-274.YamanakaYHonmaSHonmaK-i.Mistimed wheel running interferes with re-entrainment of circadian Per1 rhythms in the mouse skeletal muscle and lung. Genes Cells.2016;21(3):264-274.10.1111/gtc.12336Search in Google Scholar
Wolff G, Esser KA. Scheduled exercise phase shifts the circadian clock in skeletal Muscle. Med Sci Sports Exerc. 2012;44(9):1663-1670.WolffGEsserKA.Scheduled exercise phase shifts the circadian clock in skeletal Muscle. Med Sci Sports Exerc.2012;44(9):1663-1670.10.1249/MSS.0b013e318255cf4cSearch in Google Scholar
Buxton OM, Lee CW, L’Hermite-Baleriaux M, Turek FW, Van Cauter E. Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am J Physiol Regul Integr Comp Physiol. 2003;284(3):R714-R724.BuxtonOMLeeCWL’Hermite-BaleriauxMTurekFWVan CauterE.Exercise elicits phase shifts and acute alterations of melatonin that vary with circadian phase. Am J Physiol Regul Integr Comp Physiol.2003;284(3):R714-R724.10.1152/ajpregu.00355.2002Search in Google Scholar
Miyazaki T, Hashimoto S, Masubuchi S, Honma S, Honma KI. Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise. Am J Physiol Regul Integr Comp Physiol. 2001;281(1):R197-R205.MiyazakiTHashimotoSMasubuchiSHonmaSHonmaKI.Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise. Am J Physiol Regul Integr Comp Physiol.2001;281(1):R197-R205.10.1152/ajpregu.2001.281.1.R197Search in Google Scholar
Van Reeth O, Sturis J, Byrne MM, Blackman JD, L’Hermite-Baleriaux M, Leproult R, et al. Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men. Am J Physiol Endocrin Metab. 1994;266(6):E964-E974.Van ReethOSturisJByrneMMBlackmanJDL’Hermite-BaleriauxMLeproultRet al.Nocturnal exercise phase delays circadian rhythms of melatonin and thyrotropin secretion in normal men. Am J Physiol Endocrin Metab.1994;266(6):E964-E974.10.1152/ajpendo.1994.266.6.E964Search in Google Scholar
Barger LK, Wright Jr KP, Hughes RJ, Czeisler CA. Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light. Am J Physiol Regul Integr Comp Physiol. 2004;286(6):R1077-R1084.BargerLKWright JrKPHughesRJCzeislerCA.Daily exercise facilitates phase delays of circadian melatonin rhythm in very dim light. Am J Physiol Regul Integr Comp Physiol.2004;286(6):R1077-R1084.10.1152/ajpregu.00397.2003Search in Google Scholar
Buxton OM, Frank SA, L’Hermite-Baleriaux M, Leproult R, Turek FW, Van Cauter E. Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms. Am J Physiol Endocrin Metab. 1997;273(3):E536-E542.BuxtonOMFrankSAL’Hermite-BaleriauxMLeproultRTurekFWVan CauterE.Roles of intensity and duration of nocturnal exercise in causing phase delays of human circadian rhythms. Am J Physiol Endocrin Metab.1997;273(3):E536-E542.10.1152/ajpendo.1997.273.3.E536Search in Google Scholar
Monteleone P, Maj M, Fusco M, Orazzo C, Kemali D. Physical exercise at night blunts the nocturnal increase of plasma melatonin levels in healthy humans. Life Sci. 1990;47(22):1989-1995.MonteleonePMajMFuscoMOrazzoCKemaliD.Physical exercise at night blunts the nocturnal increase of plasma melatonin levels in healthy humans. Life Sci.1990;47(22):1989-1995.10.1016/0024-3205(90)90432-QSearch in Google Scholar
Hennessy MB. Sensitization of the plasma corticosterone response to novel environments. Physiol Behav. 1991;50(6):1175-1179.HennessyMB.Sensitization of the plasma corticosterone response to novel environments. Physiol Behav.1991;50(6):1175-1179.10.1016/0031-9384(91)90579-DSearch in Google Scholar
Ohnishi N, Tahara Y, Kuriki D, Haraguchi A, Shibata S. Warm water bath stimulates phase-shifts of the peripheral circadian clocks in PER2::LUCIFERASE mouse. PLoS ONE. 2014;9(6):e100272.OhnishiNTaharaYKurikiDHaraguchiAShibataS.Warm water bath stimulates phase-shifts of the peripheral circadian clocks in PER2::LUCIFERASE mouse. PLoS ONE.2014;9(6):e100272.10.1371/journal.pone.0100272Search in Google Scholar
Damiola F, Le Minli N, Preitner N, Kornmann B, Fleury-Olela F, Schibler U. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev. 2000;14(23):2950-2961.DamiolaFLe MinliNPreitnerNKornmannBFleury-OlelaFSchiblerU.Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev.2000;14(23):2950-2961.10.1101/gad.183500Search in Google Scholar
Stokkan KA, Yamazaki S, Tei H, Sakaki Y, Menaker M. Entrainment of the circadian clock in the liver by feeding. Science. 2001;291(5503):490-493.StokkanKAYamazakiSTeiHSakakiYMenakerM.Entrainment of the circadian clock in the liver by feeding. Science.2001;291(5503):490-493.10.1126/science.291.5503.490Search in Google Scholar
Hara R, Wan K, Wakamatsu H, Aida R, Moriya T, Akiyama M, et al. Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes Cells. 2001;6(3):269-278.HaraRWanKWakamatsuHAidaRMoriyaTAkiyamaMet al.Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus. Genes Cells.2001;6(3):269-278.10.1046/j.1365-2443.2001.00419.xSearch in Google Scholar
Oishi K, Miyazaki K, Ishida N. Functional CLOCK is not involved in the entrainment of peripheral clocks to the restricted feeding: entrainable expression of mPer2 and BMAL1 mRNAs in the heart of Clock mutant mice on jcl:ICR background. Biochem Biophys Res Commun. 2002;298(2):198-202.OishiKMiyazakiKIshidaN.Functional CLOCK is not involved in the entrainment of peripheral clocks to the restricted feeding: entrainable expression of mPer2 and BMAL1 mRNAs in the heart of Clock mutant mice on jcl:ICR background. Biochem Biophys Res Commun.2002;298(2):198-202.10.1016/S0006-291X(02)02427-0Search in Google Scholar
Mendoza J, Graff C, Dardente H, Pevet P, Challet E. Feeding cues alter clock gene oscillations and photic responses in the suprachiasmatic nuclei of mice exposed to a light/dark cycle. J Neurosci. 2005;25(6):1514-1522.MendozaJGraffCDardenteHPevetPChalletE.Feeding cues alter clock gene oscillations and photic responses in the suprachiasmatic nuclei of mice exposed to a light/dark cycle. J Neurosci.2005;25(6):1514-1522.10.1523/JNEUROSCI.4397-04.2005Search in Google Scholar
Wu T, Jin Y, Ni Y, Zhang D, Kato H, Fu Z. Effects of light cues on re-entrainment of the food-dominated peripheral clocks in mammals. Gene. 2008;419(1-2):27-34.WuTJinYNiYZhangDKatoHFuZ.Effects of light cues on re-entrainment of the food-dominated peripheral clocks in mammals. Gene.2008;419(1-2):27-34.10.1016/j.gene.2008.04.010Search in Google Scholar
Saini C, Liani A, Curie T, Gos P, Kreppel F, Emmenegger Y, et al. Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks. Genes Dev. 2013;27(13):1526-1536.SainiCLianiACurieTGosPKreppelFEmmeneggerYet al.Real-time recording of circadian liver gene expression in freely moving mice reveals the phase-setting behavior of hepatocyte clocks. Genes Dev.2013;27(13):1526-1536.10.1101/gad.221374.113Search in Google Scholar
Hamaguchi Y, Tahara Y, Hitosugi M, Shibata S. Impairment of circadian rhythms in peripheral clocks by constant light Is partially reversed by scheduled feeding or exercise. J Biol Rhythms. 2015;30(6):533-542.HamaguchiYTaharaYHitosugiMShibataS.Impairment of circadian rhythms in peripheral clocks by constant light Is partially reversed by scheduled feeding or exercise. J Biol Rhythms.2015;30(6):533-542.10.1177/0748730415609727Search in Google Scholar
Oishi K, Kasamatsu M, Ishida N. Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding. Biochem Biophys Res Commun. 2004;317(2):330-334.OishiKKasamatsuMIshidaN.Gene- and tissue-specific alterations of circadian clock gene expression in streptozotocin-induced diabetic mice under restricted feeding. Biochem Biophys Res Commun.2004;317(2):330-334.10.1016/j.bbrc.2004.03.055Search in Google Scholar
Sujino M, Furukawa K, Koinuma S, Fujioka A, Nagano M, Iigo M, et al. Differential entrainment of peripheral clocks in the rat by glucocorticoid and feeding. Endocrinology. 2012;153(5):2277-2286.SujinoMFurukawaKKoinumaSFujiokaANaganoMIigoMet al.Differential entrainment of peripheral clocks in the rat by glucocorticoid and feeding. Endocrinology.2012;153(5):2277-2286.10.1210/en.2011-1794Search in Google Scholar
Yoshida C, Shikata N, Seki S, Koyama N, Noguchi Y. Early nocturnal meal skipping alters the peripheral clock and increases lipogenesis in mice. Nutr Metab. 2012;9:78.YoshidaCShikataNSekiSKoyamaNNoguchiY.Early nocturnal meal skipping alters the peripheral clock and increases lipogenesis in mice. Nutr Metab.2012;9:78.10.1186/1743-7075-9-78Search in Google Scholar
Guo H, Brewer JM, Champhekar A, Harris RBS, Bittman EL. Differential control of peripheral circadian rhythms by suprachiasmatic-dependent neural signals. Proc Natl Acad Sci USA. 2005;102(8):3111-3116.GuoHBrewerJMChamphekarAHarrisRBSBittmanEL.Differential control of peripheral circadian rhythms by suprachiasmatic-dependent neural signals. Proc Natl Acad Sci USA.2005;102(8):3111-3116.10.1073/pnas.0409734102Search in Google Scholar
Hughes ME, DiTacchio L, Hayes KR, Vollmers C, Pulivarthy S, Baggs JE, et al. Harmonics of circadian gene transcription in mammals. PLoS Genetics. 2009;5(4):e1000442.HughesMEDiTacchioLHayesKRVollmersCPulivarthySBaggsJEet al.Harmonics of circadian gene transcription in mammals. PLoS Genetics.2009;5(4):e1000442.10.1371/journal.pgen.1000442Search in Google Scholar
Iwanaga H, Yano M, Miki H, Okada K, Azama T, Takiguchi S, et al. Per2 gene expressions in the suprachiasmatic nucleus and liver differentially respond to nutrition factors in rats. J Parenter Enteral Nutr. 2005;29(3):157-161.IwanagaHYanoMMikiHOkadaKAzamaTTakiguchiSet al.Per2 gene expressions in the suprachiasmatic nucleus and liver differentially respond to nutrition factors in rats. J Parenter Enteral Nutr.2005;29(3):157-161.10.1177/0148607105029003157Search in Google Scholar
Narishige S, Kuwahara M, Shinozaki A, Okada S, Ikeda Y, Kamagata M, et al. Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice. Br J Pharmacol. 2014;171(24):5858-5869.NarishigeSKuwaharaMShinozakiAOkadaSIkedaYKamagataMet al.Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice. Br J Pharmacol.2014;171(24):5858-5869.10.1111/bph.12890Search in Google Scholar
Sherman H, Gutman R, Chapnik N, Meylan J, Le Coutre J, Froy O. Caffeine alters circadian rhythms and expression of disease and metabolic markers. Int J Biochem Cell Biol. 2011;43(5):829-838.ShermanHGutmanRChapnikNMeylanJLe CoutreJFroyO.Caffeine alters circadian rhythms and expression of disease and metabolic markers. Int J Biochem Cell Biol.2011;43(5):829-838.10.1016/j.biocel.2011.02.008Search in Google Scholar
Wright KP, Jr., Badia P, Myers BL, Plenzler SC, Hakel M. Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans. Brain Res. 1997;747(1):78-84.WrightKPJr.BadiaPMyersBLPlenzlerSCHakelM.Caffeine and light effects on nighttime melatonin and temperature levels in sleep-deprived humans. Brain Res.1997;747(1):78-84.10.1016/S0006-8993(96)01268-1Search in Google Scholar
Burke TM, Markwald RR, McHill AW, Chinoy ED, Snider JA, Bessman SC, et al. Effects of caffeine on the human circadian clock in vivo and in vitro. Sci Transl Med. 2015;7(305):5125.BurkeTMMarkwaldRRMcHillAWChinoyEDSniderJABessmanSCet al.Effects of caffeine on the human circadian clock in vivo and in vitro. Sci Transl Med.2015;7(305):5125.10.1126/scitranslmed.aac5125Search in Google Scholar
Karlsson B, Knutsson A, Lindahl B. Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27 485 people. Occup Environ Med. 2001;58(11):747-752.KarlssonBKnutssonALindahlB.Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27 485 people. Occup Environ Med.2001;58(11):747-752.10.1136/oem.58.11.747Search in Google Scholar
Di Lorenzo L, De Pergola G, Zocchetti C, L’Abbate N, Basso A, Pannacciulli N, et al. Effect of shift work on body mass index: results of a study performed in 319 glucose-tolerant men working in a Southern Italian industry. Int J Obes. 2003;27(11):1353-1358.Di LorenzoLDe PergolaGZocchettiCL’AbbateNBassoAPannacciulliNet al.Effect of shift work on body mass index: results of a study performed in 319 glucose-tolerant men working in a Southern Italian industry. Int J Obes.2003;27(11):1353-1358.10.1038/sj.ijo.0802419Search in Google Scholar
Wang XS, Armstrong MEG, Cairns BJ, Key TJ, Travis RC. Shift work and chronic disease: the epidemiological evidence. Occup Med. 2011;61(2):78-89.WangXSArmstrongMEGCairnsBJKeyTJTravisRC.Shift work and chronic disease: the epidemiological evidence. Occup Med.2011;61(2):78-89.10.1093/occmed/kqr001Search in Google Scholar
Karlsson BH, Knutsson AK, Lindahl BO, Alfredsson LS. Metabolic disturbances in male workers with rotating three-shift work. Result of the WOLF study. Int Arch Occup Environ Health. 2003;76(6):424-430.KarlssonBHKnutssonAKLindahlBOAlfredssonLS.Metabolic disturbances in male workers with rotating three-shift work. Result of the WOLF study. Int Arch Occup Environ Health.2003;76(6):424-430.10.1007/s00420-003-0440-ySearch in Google Scholar
Al-Naimi S, Hampton SM, Richard P, Tzung C, Morgan LM. Postprandial metabolic profiles following meals and snacks eaten during simulated night and day shift work. Chronobiol Int. 2004;21(6):937-947.Al-NaimiSHamptonSMRichardPTzungCMorganLM.Postprandial metabolic profiles following meals and snacks eaten during simulated night and day shift work. Chronobiol Int.2004;21(6):937-947.10.1081/CBI-200037171Search in Google Scholar
Lund J, Arendt J, Hampton SM, English J, Morgan LM. Postprandial hormone and metabolic responses amongst shift workers in Antarctica. J Endocrinol. 2001;171(3):557-564.LundJArendtJHamptonSMEnglishJMorganLM.Postprandial hormone and metabolic responses amongst shift workers in Antarctica. J Endocrinol.2001;171(3):557-564.10.1677/joe.0.1710557Search in Google Scholar
Erren TC, Pape HG, Reiter RJ, Piekarski C. Chronodisruption and cancer. Naturwissenschaften. 2008;95(5):367-382.ErrenTCPapeHGReiterRJPiekarskiC.Chronodisruption and cancer. Naturwissenschaften.2008;95(5):367-382.10.1007/s00114-007-0335-ySearch in Google Scholar
Morris CJ, Yang JN, Garcia JI, Myers S, Bozzi I, Wang W, et al. Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans. Proc Natl Acad Sci USA. 2015;112(17):E2225-E2234.MorrisCJYangJNGarciaJIMyersSBozziIWangWet al.Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans. Proc Natl Acad Sci USA.2015;112(17):E2225-E2234.10.1073/pnas.1418955112Search in Google Scholar
Grant C, Coates A, Dorrian J, Kennaway D, Wittert G, Heilbronn L, et al. Eating on simulated night shift effects glucose response to breakfast: pilot study. FASEB J. 2016;30(1(suppl)):1160.2.GrantCCoatesADorrianJKennawayDWittertGHeilbronnLet al.Eating on simulated night shift effects glucose response to breakfast: pilot study. FASEB J.2016;30(1(suppl)):1160.2.Search in Google Scholar
Lewy AJ, Bauer VK, Ahmed S, Thomas KH, Cutler NL, Singer CM, et al. The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light. Chronobiol Int. 1998;15(1):71-83.LewyAJBauerVKAhmedSThomasKHCutlerNLSingerCMet al.The human phase response curve (PRC) to melatonin is about 12 hours out of phase with the PRC to light. Chronobiol Int.1998;15(1):71-83.10.3109/07420529808998671Search in Google Scholar
Poirel VJ, Boggio V, Dardente H, Pevet P, Masson-Pevet M, Gauer F. Contrary to other non-photic cues, acute melatonin injection does not induce immediate changes of clock gene mRNA expression in the rat suprachiasmatic nuclei. Neurosci. 2003;120(3):745-755.PoirelVJBoggioVDardenteHPevetPMasson-PevetMGauerF.Contrary to other non-photic cues, acute melatonin injection does not induce immediate changes of clock gene mRNA expression in the rat suprachiasmatic nuclei. Neurosci.2003;120(3):745-755.10.1016/S0306-4522(03)00344-0Search in Google Scholar
Mistlberger RE, Skene DJ. Nonphotic entrainment in humans? J Biol Rhythms. 2005;20(4):339-352.MistlbergerRESkeneDJ.Nonphotic entrainment in humans?J Biol Rhythms.2005;20(4):339-352.10.1177/0748730405277982Search in Google Scholar
Skene DJ. Optimization of light and melatonin to phase-shift human circadian rhythms. J Neuroendocrinol. 2003;15(4):438-441.SkeneDJ.Optimization of light and melatonin to phase-shift human circadian rhythms. J Neuroendocrinol.2003;15(4):438-441.10.1046/j.1365-2826.2003.01006.xSearch in Google Scholar
Boulos Z, Rusak B. Circadian phase response curves for dark pulses in the hamster. J Comp Physiol. 1982;146(4):411-417.BoulosZRusakB.Circadian phase response curves for dark pulses in the hamster. J Comp Physiol.1982;146(4):411-417.10.1007/BF00609437Search in Google Scholar
Lockley SW, Skene DJ, Arendt J, Tabandeh H, Bird AC, Defrance R. Relationship between melatonin rhythms and visual loss in the blind. J Clin Endocrinol Metab. 1997;82(11):3763-3770.LockleySWSkeneDJArendtJTabandehHBirdACDefranceR.Relationship between melatonin rhythms and visual loss in the blind. J Clin Endocrinol Metab.1997;82(11):3763-3770.10.1210/jc.82.11.3763Search in Google Scholar
Sack RL, Lewy AJ, Blood ML, Keith LD, Nakagawa H. Circadian rhythm abnormalities in totally blind people: Incidence and clinical significance. J Clin Endocrinol Metab. 1992;75(1):127-134.SackRLLewyAJBloodMLKeithLDNakagawaH.Circadian rhythm abnormalities in totally blind people: Incidence and clinical significance. J Clin Endocrinol Metab.1992;75(1):127-134.Search in Google Scholar
Skene DJ, Lockley SW, Thapan K, Arendt J. Effects of light on human circadian rhythms. Reprod Nutr Dev. 1999;39(3):295-304.SkeneDJLockleySWThapanKArendtJ.Effects of light on human circadian rhythms. Reprod Nutr Dev.1999;39(3):295-304.10.1051/rnd:19990302Search in Google Scholar
Lockley SW, Dijk DJ, Kosti O, Skene DJ, Arendt J. Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind. J Sleep Res. 2008;17(2):207-216.LockleySWDijkDJKostiOSkeneDJArendtJ.Alertness, mood and performance rhythm disturbances associated with circadian sleep disorders in the blind. J Sleep Res.2008;17(2):207-216.10.1111/j.1365-2869.2008.00656.xSearch in Google Scholar
Emens JS, Lewy AJ, Lefler BJ, Sack RL. Relative coordination to unknown “weak zeitgebers” in free-running blind individuals. J Biol Rhythms. 2005;20(2):159-167.EmensJSLewyAJLeflerBJSackRL.Relative coordination to unknown “weak zeitgebers” in free-running blind individuals. J Biol Rhythms.2005;20(2):159-167.10.1177/0748730404273294Search in Google Scholar
Emens JS, Laurie AL, Songer JB, Lewy AJ. Non-24-hour disorder in blind individuals revisited: variability and the influence of environmental time cues. Sleep. 2013;36(7):1091-1100.EmensJSLaurieALSongerJBLewyAJ.Non-24-hour disorder in blind individuals revisited: variability and the influence of environmental time cues. Sleep.2013;36(7):1091-1100.10.5665/sleep.2818Search in Google Scholar
Lockley SW, Skene DJ, James K, Thapan K, Wright J, Arendt J. Melatonin administration can entrain the free-running circadian system of blind subjects. J Endocrinol. 2000;164(1):R1-R6.LockleySWSkeneDJJamesKThapanKWrightJArendtJ.Melatonin administration can entrain the free-running circadian system of blind subjects. J Endocrinol.2000;164(1):R1-R6.10.1677/joe.0.164r001Search in Google Scholar
Sack RL, Brandes RW, Kendall AR, Lewy AJ. Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med. 2000;343(15):1070-1077.SackRLBrandesRWKendallARLewyAJ.Entrainment of free-running circadian rhythms by melatonin in blind people. N Engl J Med.2000;343(15):1070-1077.10.1056/NEJM200010123431503Search in Google Scholar
Hack LM, Lockley SW, Arendt J, Skene DJ. The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects. J Biol Rhythms. 2003;18(5):420-429.HackLMLockleySWArendtJSkeneDJ.The effects of low-dose 0.5-mg melatonin on the free-running circadian rhythms of blind subjects. J Biol Rhythms.2003;18(5):420-429.10.1177/0748730403256796Search in Google Scholar
Roth T, Nir T, Zisapel N. Prolonged release melatonin for improving sleep in totally blind subjects: a pilot placebo-controlled multicenter trial. Nat Sci Sleep. 2015;7:13-23.RothTNirTZisapelN.Prolonged release melatonin for improving sleep in totally blind subjects: a pilot placebo-controlled multicenter trial. Nat Sci Sleep.2015;7:13-23.Search in Google Scholar
