<abstract xmlns="http://www.w3.org/1999/xhtml"><sec><h3>Aim</h3><p>To assess the sagittal soft tissue morphology of patients with acromegaly in comparison with a healthy control group.</p></sec><sec><h3>Methods</h3><p>Twenty-seven patients with acromegaly (11 male, 16 female; mean age 47.3 ± 11.5 years) and 30 healthy subjects (15 male, 15 female; mean age 42.2 ± 17.4 years) were included in the study. Linear and angular measurements were made on lateral cephalograms to evaluate soft tissue and skeletal characteristics. The intergroup comparisons were analysed with the Student’s t-test.</p></sec><sec><h3>Results</h3><p>Facial convexity (<italic>p</italic> &lt; 0.01) and the nasolabial angle (<italic>p</italic> &lt; 0.001) were reduced in patients with acromegaly, whereas nose prominence (<italic>p</italic> &lt; 0.01), upper lip sulcus depth (<italic>p</italic> &lt; 0.01), upper lip thickness (<italic>p</italic> &lt; 0.01), basic upper lip thickness (<italic>p</italic> &lt; 0.01), lower lip protrusion (<italic>p</italic> &lt; 0.05), mentolabial sulcus depth (<italic>p</italic> &lt; 0.05) and soft tissue chin thickness (<italic>p</italic> &lt; 0.001) were increased. Anterior cranial base length (<italic>p</italic> &lt; 0.05), the supraorbital ridge (<italic>p</italic> &lt; 0.01), the length of the maxilla and mandible (<italic>p</italic> &lt; 0.001, <italic>p</italic> &lt; 0.01, respectively) were significantly increased, and mandibular prognathism was an acromegalic feature (<italic>p</italic> &lt; 0.05).</p></sec><sec><h3>Conclusion</h3><p>Acromegalic coarsening and thickening of the craniofacial soft tissues was identified from lateral cephalograms, which may therefore contribute to early diagnosis when evaluated together with other changes caused by the disease.</p></sec></abstract>

AimTo assess the sagittal soft tissue morphology of patients with acromegaly in comparison with a healthy control group.MethodsTwenty-seven patients with acromegaly (11 male, 16 female; mean age 47.3 ± 11.5 years) and 30 healthy subjects (15 male, 15 female; mean age 42.2 ± 17.4 years) were included in the study. Linear and angular measurements were made on lateral cephalograms to evaluate soft tissue and skeletal characteristics. The intergroup comparisons were analysed with the Student’s t-test.ResultsFacial convexity (p < 0.01) and the nasolabial angle (p < 0.001) were reduced in patients with acromegaly, whereas nose prominence (p < 0.01), upper lip sulcus depth (p < 0.01), upper lip thickness (p < 0.01), basic upper lip thickness (p < 0.01), lower lip protrusion (p < 0.05), mentolabial sulcus depth (p < 0.05) and soft tissue chin thickness (p < 0.001) were increased. Anterior cranial base length (p < 0.05), the supraorbital ridge (p < 0.01), the length of the maxilla and mandible (p < 0.001, p < 0.01, respectively) were significantly increased, and mandibular prognathism was an acromegalic feature (p < 0.05).ConclusionAcromegalic coarsening and thickening of the craniofacial soft tissues was identified from lateral cephalograms, which may therefore contribute to early diagnosis when evaluated together with other changes caused by the disease.

Cephalometric assessment of soft tissue morphology of patients with acromegaly

Australasian Orthodontic Journal

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Cephalometric assessment of soft tissue morphology of patients with acromegaly"}

AimTo assess the sagittal soft tissue morphology of patients with acromegaly in comparison with a healthy control group.MethodsTwenty-seven patients with...

Cephalometric assessment of soft tissue morphology of patients with acromegaly

Published Online: Jul 30, 2021

Page range: 48 - 54

Received: Aug 01, 2015

Accepted: Feb 01, 2016

DOI: https://doi.org/10.21307/aoj-2020-112

© 2016 Nehir Canigur Bavbek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.