<abstract xmlns="http://www.w3.org/1999/xhtml"><sec><h3>Objective</h3><p>To investigate the prevalence of cervical vertebral anomalies (CVA) in a group of patients presenting with cleft lip and palate (CLP) and to compare with a non-cleft population.</p></sec><sec><h3>Material and methods</h3><p>The sample comprised of 150 lateral cephalograms of non-syndromic patients with CLP and 150 non-cleft age-matched controls. The age range of both groups covered 6 to 20 years. An expert radiologist blinded to the cleft status evaluated the cephalograms for CVA and categorised them into normal, fusion, dehiscence and multiple cervical anomalies. The cleft group was subdivided according to the types of cleft (UCLP/ BCLP/ CPO) and gender (male/female). The CVA prevalence was compared between the cleft and non-cleft patients.</p></sec><sec><h3>Results</h3><p>The prevalence of CVA was 37.7% and 20.7% in cleft and non-cleft patients, respectively. The difference was statistically significant with a <italic>p</italic>-value &lt;0.01. Of the types of clefts, a left UCLP had the highest prevalence of CVA (47.2%), with fusion (35.8%) most commonly seen. On comparing CLP with CPO, no significant variation was observed between the types of anomalies.</p></sec><sec><h3>Conclusions</h3><p>A high prevalence of CVA was observed in cleft patients compared with non-cleft subjects. The prevalence of CVA was similar between males and females. The practitioner should carefully evaluate the lateral cephalogram of CLP patients for CVA, which otherwise may remain undetected and lead to neurological symptoms later in life.</p></sec></abstract>

ObjectiveTo investigate the prevalence of cervical vertebral anomalies (CVA) in a group of patients presenting with cleft lip and palate (CLP) and to compare with a non-cleft population.Material and methodsThe sample comprised of 150 lateral cephalograms of non-syndromic patients with CLP and 150 non-cleft age-matched controls. The age range of both groups covered 6 to 20 years. An expert radiologist blinded to the cleft status evaluated the cephalograms for CVA and categorised them into normal, fusion, dehiscence and multiple cervical anomalies. The cleft group was subdivided according to the types of cleft (UCLP/ BCLP/ CPO) and gender (male/female). The CVA prevalence was compared between the cleft and non-cleft patients.ResultsThe prevalence of CVA was 37.7% and 20.7% in cleft and non-cleft patients, respectively. The difference was statistically significant with a p-value <0.01. Of the types of clefts, a left UCLP had the highest prevalence of CVA (47.2%), with fusion (35.8%) most commonly seen. On comparing CLP with CPO, no significant variation was observed between the types of anomalies.ConclusionsA high prevalence of CVA was observed in cleft patients compared with non-cleft subjects. The prevalence of CVA was similar between males and females. The practitioner should carefully evaluate the lateral cephalogram of CLP patients for CVA, which otherwise may remain undetected and lead to neurological symptoms later in life.

Prevalence of cervical vertebrae anomalies in patients with cleft lip and palate

Australasian Orthodontic Journal

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Prevalence of cervical vertebrae anomalies in patients with cleft lip and palate"}

ObjectiveTo investigate the prevalence of cervical vertebral anomalies (CVA) in a group of patients presenting with cleft lip and palate (CLP) and to compare...

Prevalence of cervical vertebrae anomalies in patients with cleft lip and palate

Published Online: Jul 20, 2021

Page range: 46 - 52

Received: Oct 01, 2018

Accepted: Mar 01, 2019

DOI: https://doi.org/10.21307/aoj-2020-032

© 2019 Om Prakash Kharbanda et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.