<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Collectively, Lewy Body Dementia (LBD) including Parkinson’s Disease Dementia (PDD) and dementia with Lewy Bodies (DLB) account for the second leading type of dementia following Alzheimer’s disease (AD) (<xref ref-type="bibr" rid="j_ajon-2022-005_ref_16">Lee et al., 2019</xref>). Despite revised consensus criteria, detection rates in routine clinical practice remain poor (<xref ref-type="bibr" rid="j_ajon-2022-005_ref_35">Vann Jones &amp; O’Brien, 2013</xref>) with cases commonly misdiagnosed as AD (<xref ref-type="bibr" rid="j_ajon-2022-005_ref_22">McKeith et al., 2017</xref>).</p>
<p>Diagnosis can be challenging due to the presentation of an extensive range of autonomic, motor, sleep, cognitive and neuropsychiatric symptoms which can vary within a person and between individuals (<xref ref-type="bibr" rid="j_ajon-2022-005_ref_30">Taylor et al., 2020</xref>). Given the disparity in management and prognosis of LBD compared to other dementias (<xref ref-type="bibr" rid="j_ajon-2022-005_ref_9">Fujishiro et al., 2013</xref>), the timing and accuracy of diagnosis is of great consequence.</p>
</abstract>

Collectively, Lewy Body Dementia (LBD) including Parkinson’s Disease Dementia (PDD) and dementia with Lewy Bodies (DLB) account for the second leading type of dementia following Alzheimer’s disease (AD) (Lee et al., 2019). Despite revised consensus criteria, detection rates in routine clinical practice remain poor (Vann Jones & O’Brien, 2013) with cases commonly misdiagnosed as AD (McKeith et al., 2017).
Diagnosis can be challenging due to the presentation of an extensive range of autonomic, motor, sleep, cognitive and neuropsychiatric symptoms which can vary within a person and between individuals (Taylor et al., 2020). Given the disparity in management and prognosis of LBD compared to other dementias (Fujishiro et al., 2013), the timing and accuracy of diagnosis is of great consequence.

Lewy body Dementia: What are the challenges of early and accurate diagnosis?

Australasian Journal of Neuroscience

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

A review of the neuroscience literature to inform clinical practice

Collectively, Lewy Body Dementia (LBD) including Parkinson’s Disease Dementia (PDD) and dementia with Lewy Bodies (DLB) account for the second leading type of...

Lewy body Dementia: What are the challenges of early and accurate diagnosis?

Published Online: Jul 11, 2022

Page range: 40 - 51

DOI: https://doi.org/10.21307/ajon-2022-005

© 2022 Madelaine B. Rañola, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.