<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Starting from the end of 2019 the new SARs-CoV-2 virus, in the period of a few months, had spread to 210 countries and its territories. The Wuhan wild animal market, in Hubei province, China is considered the epicenter of this pandemic. WHO declared the name COVID-19 to designate the disease caused by the SARS-CoV-2 virus. It is the third coronavirus pandemic after SARS in 2002–2003 and MERS-CoV in 2012. Genome sequencing of this new COVID-19/SARS-CoV-2 virus shows slight genetic diversity when compared to other coronaviruses. Owing to its pathogenesis, and less known replication cycle, no universal antiviral treatment can be applied and vaccine preparation is still a larger challenge. The present article will highlight transmission, pandemic status, genetic diversity current antiviral therapy, and vaccine trials for COVID-19.</p>
<p>1. Introduction. 2. Pathogenesis of coronaviruses. 3. Genetic diversity. 4. Transmission. 5. Vaccination strategies against COVID-19. 6. In Process Vaccination strategies against COVID-19. 7. Lack of antiviral treatment and antiviral treatment studies. 8. Precautions. 9. Conclusions</p>
</abstract>

Starting from the end of 2019 the new SARs-CoV-2 virus, in the period of a few months, had spread to 210 countries and its territories. The Wuhan wild animal market, in Hubei province, China is considered the epicenter of this pandemic. WHO declared the name COVID-19 to designate the disease caused by the SARS-CoV-2 virus. It is the third coronavirus pandemic after SARS in 2002–2003 and MERS-CoV in 2012. Genome sequencing of this new COVID-19/SARS-CoV-2 virus shows slight genetic diversity when compared to other coronaviruses. Owing to its pathogenesis, and less known replication cycle, no universal antiviral treatment can be applied and vaccine preparation is still a larger challenge. The present article will highlight transmission, pandemic status, genetic diversity current antiviral therapy, and vaccine trials for COVID-19.
1. Introduction. 2. Pathogenesis of coronaviruses. 3. Genetic diversity. 4. Transmission. 5. Vaccination strategies against COVID-19. 6. In Process Vaccination strategies against COVID-19. 7. Lack of antiviral treatment and antiviral treatment studies. 8. Precautions. 9. Conclusions

Novel Sars-Cov-2 Pandemic Transmission With Ongoing Antiviral Therapies And Vaccine Design

Advancements of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Starting from the end of 2019 the new SARs-CoV-2 virus, in the period of a few months, had spread to 210 countries and its territories. The Wuhan wild animal...

Novel Sars-Cov-2 Pandemic Transmission With Ongoing Antiviral Therapies And Vaccine Design

Article Category: research-article

Published Online: Mar 24, 2021

Page range: 13 - 20

Received: Jul 01, 2020

Accepted: Oct 01, 2020

DOI: https://doi.org/10.21307/PM-2021.60.1.02

Keywords
SARs-CoV-2, WHO, viral genome, COVID-19

© 2021 Wenbing Yameen et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Novel Sars-Cov-2 Pandemic Transmission With Ongoing Antiviral Therapies And Vaccine Design

Article Category: research-article

Published Online: Mar 24, 2021

Page range: 13 - 20

Received: Jul 01, 2020

Accepted: Oct 01, 2020

DOI: https://doi.org/10.21307/PM-2021.60.1.02

KeywordsSARs-CoV-2, WHO, viral genome, COVID-19

© 2021 Wenbing Yameen et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
SARs-CoV-2, WHO, viral genome, COVID-19