Mechanisms Of Dermatophyte Resistance To Antifungal Substances

1. Akerfelt M., Morimoto R.I., Sistonen L.: Heat shock factors: integrators of cell stress, development and lifespan. Nat. Rev. Mol. Cell Biol. 11, 545–555 (2010) Akerfelt M. Morimoto R.I. Sistonen L. Heat shock factors: integrators of cell stress, development and lifespan Nat. Rev. Mol. Cell Biol. 11 545 555 201010.1038/nrm2938340235620628411 Search in Google Scholar

2. Arrese J.E., Pierard-Franchimont C., Pierard G.E.: A plea to bridge the gap between antifungals and the management of onychomycosis. Am. J. Clin. Dermatol. 2, 281–284 (2001) Arrese J.E. Pierard-Franchimont C. Pierard G.E. A plea to bridge the gap between antifungals and the management of onychomycosis Am. J. Clin. Dermatol. 2 281 284 200110.2165/00128071-200102050-0000211721646 Search in Google Scholar

3. Badali H., Mohammadi R., Mashedi O., de Hoog G.S., Meis J.F.: In vitro susceptibility patterns of clinically important Trichophyton and Epidermophyton species against nine antifungal drugs. Mycoses, 58, 303–307 (2015) Badali H. Mohammadi R. Mashedi O. de Hoog G.S. Meis J.F. In vitro susceptibility patterns of clinically important Trichophyton and Epidermophyton species against nine antifungal drugs Mycoses 58 303 307 201510.1111/myc.1231525757042 Search in Google Scholar

4. Bignell E., Negrete-Urtasun S., Calcagno A.M., Haynes K., Arst H.N.J., Rogers T.: The Aspergillus pH-responsive transcription factor PacC regulates virulence. Mol. Microbiol. 55, 1072–1084 (2005) Bignell E. Negrete-Urtasun S. Calcagno A.M. Haynes K. Arst H.N.J. Rogers T. The Aspergillus pH-responsive transcription factor PacC regulates virulence Mol. Microbiol. 55 1072 1084 200510.1111/j.1365-2958.2004.04472.x15686555 Search in Google Scholar

5. Brasch J., Martins B.S., Christophers E.: Enzyme release by Trichophyton rubrum depends on nutritional conditions. Mycoses, 34, 365–368 (1991) Brasch J. Martins B.S. Christophers E. Enzyme release by Trichophyton rubrum depends on nutritional conditions Mycoses 34 365 368 199110.1111/j.1439-0507.1991.tb00795.x1726475 Search in Google Scholar

6. Brilhante R.S.N., Rocha M.F.G. i wsp.: Quantitative and structural analyses of the in vitro and ex vivo biofilm-forming ability of dermatophytes. J. Med. Microbiol. 66, 1045–1052 (2017) Brilhante R.S.N. Rocha M.F.G. i wsp.: Quantitative and structural analyses of the in vitro and ex vivo biofilm-forming ability of dermatophytes J. Med. Microbiol. 66 1045 1052 201710.1099/jmm.0.00052828708048 Search in Google Scholar

7. Burkhart C.N., Burkhart C.G., Gupta A.K.: Dermatophytoma: Recalcitrance to treatment because of existence of fungal biofilm. J. Am. Acad. Dermatol. 47, 629–631 (2002) Burkhart C.N. Burkhart C.G. Gupta A.K. Dermatophytoma: Recalcitrance to treatment because of existence of fungal biofilm J. Am. Acad. Dermatol. 47 629 631 200210.1067/mjd.2002.12469912271316 Search in Google Scholar

8. Burmester A., Shelest E., Glöckner G., Heddergott C., Schindler S., Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., i wsp.: Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi. Genome Biol. 12, R7 (2011) Burmester A. Shelest E. Glöckner G. Heddergott C. Schindler S. Staib P. Heidel A. Felder M. Petzold A. Szafranski K. Feuermann M. Pedruzzi I. Priebe S. Groth M. Winkler R. i wsp.: Comparative and functional genomics provide insights into the pathogenicity of dermatophytic fungi Genome Biol. 12 R7 201110.1186/gb-2011-12-1-r7309130521247460 Search in Google Scholar

9. Cervelatti E.P., Fachin A.L., Ferreira-Nozawa M.S., Martinez-Rossi N.M.: Molecular cloning and characterization of a novel ABC transporter gene in the human pathogen Trichophyton rubrum. Med. Mycol. 44, 141–147 (2006) Cervelatti E.P. Fachin A.L. Ferreira-Nozawa M.S. Martinez-Rossi N.M. Molecular cloning and characterization of a novel ABC transporter gene in the human pathogen Trichophyton rubrum Med. Mycol. 44 141 147 200610.1080/1369378050022044916519017 Search in Google Scholar

10. Chatterjee S., Tatu U.: Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans. PLoS Negl. Trop. Dis. 11, e0005836 (2017) Chatterjee S. Tatu U. Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans PLoS Negl. Trop. Dis. 11 e0005836 201710.1371/journal.pntd.0005836555910428783748 Search in Google Scholar

11. Coelho L.M., Aquino-Ferreira R., Maffei C.M.L., Martinez-Rossi N.M.: In vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia. J. Antimicrob. Chemother. 62, 758–761 (2008) Coelho L.M. Aquino-Ferreira R. Maffei C.M.L. Martinez-Rossi N.M. In vitro antifungal drug susceptibilities of dermatophytes microconidia and arthroconidia J. Antimicrob. Chemother. 62 758 761 200810.1093/jac/dkn24518552341 Search in Google Scholar

12. Coleman J.J., Mylonakis E.: Efflux in fungi: la piece de resistance. PLoS Pathog. 5, e1000486 (2009) Coleman J.J. Mylonakis E. Efflux in fungi: la piece de resistance PLoS Pathog. 5 e1000486 200910.1371/journal.ppat.1000486269556119557154 Search in Google Scholar

13. Cowen L.E.: The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype. Nat. Rev. Microbiol. 6, 187–198 (2008) Cowen L.E. The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype Nat. Rev. Microbiol. 6 187 198 200810.1038/nrmicro183518246082 Search in Google Scholar

14. Cowen L.E.: Hsp90 Orchestrates Stress Response Signaling Governing Fungal Drug Resistance. PLOS Pathog. 5, e1000471 (2009) Cowen L.E. Hsp90 Orchestrates Stress Response Signaling Governing Fungal Drug Resistance PLOS Pathog. 5 e1000471 200910.1371/journal.ppat.1000471272694919714223 Search in Google Scholar

15. Cowen L.E., Sanglard D., Howard S.J., Rogers P.D., Perlin D.S.: Mechanisms of Antifungal Drug Resistance. Cold Spring Harb. Perspect. Med. 5, a019752–a019752 (2014) Cowen L.E. Sanglard D. Howard S.J. Rogers P.D. Perlin D.S. Mechanisms of Antifungal Drug Resistance Cold Spring Harb. Perspect. Med. 5 a019752 a019752 201410.1101/cshperspect.a019752448495525384768 Search in Google Scholar

16. Decottignies A., Goffeau A.: Complete inventory of the yeast ABC proteins. Nat. Genet. 15, 137–145 (1997) Decottignies A. Goffeau A. Complete inventory of the yeast ABC proteins Nat. Genet. 15 137 145 199710.1038/ng0297-1379020838 Search in Google Scholar

17. Delarze E., Sanglard D.: Defining the frontiers between antifungal resistance, tolerance and the concept of persistence. Drug Resist. Updat. 23, 12–19 (2015) Delarze E. Sanglard D. Defining the frontiers between antifungal resistance, tolerance and the concept of persistence Drug Resist. Updat. 23 12 19 201510.1016/j.drup.2015.10.00126690338 Search in Google Scholar

18. Deng S., Ansari S., Ilkit M., Rafati H., Hedayati M.T., Taghizadeh-Armaki M., Nasrollahi-Omran A., Tolooe A., Zhan P., Liao W., van der Lee H.A., Verweij P.E., Seyedmousavi S.: In vitro antifungal susceptibility profiles of 12 antifungal drugs against 55 Trichophyton schoenleinii isolates from tinea capitis favosa patients in Iran, Turkey, and China. Antimicrob. Agents Chemother. 61, (2017) Deng S. Ansari S. Ilkit M. Rafati H. Hedayati M.T. Taghizadeh-Armaki M. Nasrollahi-Omran A. Tolooe A. Zhan P. Liao W. van der Lee H.A. Verweij P.E. Seyedmousavi S. In vitro antifungal susceptibility profiles of 12 antifungal drugs against 55 Trichophyton schoenleinii isolates from tinea capitis favosa patients in Iran, Turkey, and China Antimicrob. Agents Chemother. 61 201710.1128/AAC.01753-16527871327956429 Search in Google Scholar

19. Diao Y., Zhao R., Deng X., Leng W., Peng J., Jin Q.: Transcriptional profiles of Trichophyton rubrum in response to itraconazole. Med. Mycol. 47, 237–247 (2009) Diao Y. Zhao R. Deng X. Leng W. Peng J. Jin Q. Transcriptional profiles of Trichophyton rubrum in response to itraconazole Med. Mycol. 47 237 247 200910.1080/1369378080222730818663659 Search in Google Scholar

20. El-Awady R., Saleh E., Hashim A., Soliman N., Dallah A., Elrasheed A., Elakraa G.: The role of eukaryotic and prokaryotic abc transporter family in failure of chemotherapy. Front. Pharmacol. 7, 535 (2016) El-Awady R. Saleh E. Hashim A. Soliman N. Dallah A. Elrasheed A. Elakraa G. The role of eukaryotic and prokaryotic abc transporter family in failure of chemotherapy Front. Pharmacol. 7 535 201610.3389/fphar.2016.00535522343728119610 Search in Google Scholar

21. Fachin A.L., Contel E.P., Martinez-Rossi N.M.: Effect of sub-MICs of antimycotics on expression of intracellular esterase of Trichophyton rubrum. Med. Mycol. 39, 129–133 (2001) Fachin A.L. Contel E.P. Martinez-Rossi N.M. Effect of sub-MICs of antimycotics on expression of intracellular esterase of Trichophyton rubrum Med. Mycol. 39 129 133 200110.1080/714030995 Search in Google Scholar

22. Fachin A.L., Maffei C.M., Martinez-Rossi N.M.: In vitro susceptibility of Trichophyton rubrum isolates to griseofulvin and tioconazole. Induction and isolation of a resistant mutant to both antimycotic drugs. Mutant of Trichophyton rubrum resistant to griseofulvin and tioconazole. Mycopathologia, 135, 141–143 (1996) Fachin A.L. Maffei C.M. Martinez-Rossi N.M. In vitro susceptibility of Trichophyton rubrum isolates to griseofulvin and tioconazole. Induction and isolation of a resistant mutant to both antimycotic drugs. Mutant of Trichophyton rubrum resistant to griseofulvin and tioconazole Mycopathologia 135 141 143 199610.1007/BF006323349066154 Search in Google Scholar

23. Fachin A., Ferreira-Nozawa M., Maccheroni W., Martinez-Rossi N.: Role of the ABC transporter TRUMDR2 in terbinafine, 4-nitroquinoline N-oxide and ethidium bromide susceptibility in Trichophyton rubrum. J. Med. Microbiol. 55, 1093–1099 (2006) Fachin A. Ferreira-Nozawa M. Maccheroni W. Martinez-Rossi N. Role of the ABC transporter TRUMDR2 in terbinafine, 4-nitroquinoline N-oxide and ethidium bromide susceptibility in Trichophyton rubrum J. Med. Microbiol. 55 1093 1099 200610.1099/jmm.0.46522-016849730 Search in Google Scholar

24. Fanning S., Mitchell A.P.: Fungal biofilms. PLoS Pathog. 8, e1002585 (2012) Fanning S. Mitchell A.P. Fungal biofilms PLoS Pathog. 8 e1002585 201210.1371/journal.ppat.1002585332059322496639 Search in Google Scholar

25. Favre B., Ryder N.S.: Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents. Antimicrob. Agents Chemother. 40, 443–447 (1996) Favre B. Ryder N.S. Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents Antimicrob. Agents Chemother. 40 443 447 199610.1128/AAC.40.2.4431631318834895 Search in Google Scholar

26. Feng G., Leem Y.E., Levin H.L.: Transposon integration enhances expression of stress response genes. Nucleic Acids Res. 41, 775–789 (2013) Feng G. Leem Y.E. Levin H.L. Transposon integration enhances expression of stress response genes Nucleic Acids Res. 41 775 789 201310.1093/nar/gks1185355399223193295 Search in Google Scholar

27. Ferreira-Nozawa M.S., Silveira H.C.S., Ono C.J., Fachin A.L., Rossi A., Martinez-Rossi N.M.: The pH signaling transcription factor PacC mediates the growth of Trichophyton rubrum on human nail in vitro. Med. Mycol. 44, 641–645 (2006) Ferreira-Nozawa M.S. Silveira H.C.S. Ono C.J. Fachin A.L. Rossi A. Martinez-Rossi N.M. The pH signaling transcription factor PacC mediates the growth of Trichophyton rubrum on human nail in vitro Med. Mycol. 44 641 645 200610.1080/1369378060087655317071558 Search in Google Scholar

28. Friesen H., Lunz R., Doyle S., Segall J.: Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation. Genes Dev. 8, 2162–2175 (1994) Friesen H. Lunz R. Doyle S. Segall J. Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation Genes Dev. 8 2162 2175 199410.1101/gad.8.18.21627958886 Search in Google Scholar

29. Gadzalski M., Ciesielska A., Staczek P.: Bioinformatic survey of ABC transporters in dermatophytes. Gene, 576, 466–475 (2016) Gadzalski M. Ciesielska A. Staczek P. Bioinformatic survey of ABC transporters in dermatophytes Gene 576 466 475 201610.1016/j.gene.2015.10.06426524502 Search in Google Scholar

30. Garaizar J., Brena S., Bikandi J., Rementeria A., Ponton J.: Use of DNA microarray technology and gene expression profiles to investigate the pathogenesis, cell biology, antifungal susceptibility and diagnosis of Candida albicans. FEMS Yeast Res. 6, 987–998 (2006) Garaizar J. Brena S. Bikandi J. Rementeria A. Ponton J. Use of DNA microarray technology and gene expression profiles to investigate the pathogenesis, cell biology, antifungal susceptibility and diagnosis of Candida albicans FEMS Yeast Res. 6 987 998 200610.1111/j.1567-1364.2006.00108.x17042748 Search in Google Scholar

31. Ghelardi E., Celandroni F., Gueye S.A., Salvetti S., Senesi S., Bulgheroni A., Mailland F.: Potential of ergosterol synthesis inhibitors to cause resistance or cross-resistance in Trichophyton rubrum. Antimicrob. Agents Chemother. 58, 2825–2829 (2014) Ghelardi E. Celandroni F. Gueye S.A. Salvetti S. Senesi S. Bulgheroni A. Mailland F. Potential of ergosterol synthesis inhibitors to cause resistance or cross-resistance in Trichophyton rubrum Antimicrob. Agents Chemother. 58 2825 2829 201410.1128/AAC.02382-13399322524614379 Search in Google Scholar

32. Glavinas H., Krajcsi P., Cserepes J., Sarkadi B.: The role of ABC transporters in drug resistance, metabolism and toxicity. Curr. Drug Deliv. 1, 27–42 (2004) Glavinas H. Krajcsi P. Cserepes J. Sarkadi B. The role of ABC transporters in drug resistance, metabolism and toxicity Curr. Drug Deliv. 1 27 42 200410.2174/156720104348003616305368 Search in Google Scholar

33. Gnat S., Łagowski D., Nowakiewicz A., Zięba P.: Phenotypic characterization of enzymatic activity of clinical dermatophyte isolates from animals with and without skin lesions and humans. J. Appl. Microbiol. 125, 700–709 (2018) Gnat S. Łagowski D. Nowakiewicz A. Zięba P. Phenotypic characterization of enzymatic activity of clinical dermatophyte isolates from animals with and without skin lesions and humans J. Appl. Microbiol. 125 700 709 201810.1111/jam.1392129779226 Search in Google Scholar

34. Gnat S., Nowakiewicz A., Łagowski D., Zięba P.: Host- and pathogen-dependent susceptibility and predisposition to dermatophytosis. J. Med. Microbiol. 68, 823–836 (2019) Gnat S. Nowakiewicz A. Łagowski D. Zięba P. Host- and pathogen-dependent susceptibility and predisposition to dermatophytosis J. Med. Microbiol. 68 823 836 201910.1099/jmm.0.00098231050630 Search in Google Scholar

35. Gnat S., Nowakiewicz A., Zięba P.: Taxonomy of dermatophytes – the classification systems may change but the identification problems remain the same. Adv. Microbiol. 58, 49–58 (2019) Gnat S. Nowakiewicz A. Zięba P. Taxonomy of dermatophytes – the classification systems may change but the identification problems remain the same Adv. Microbiol. 58 49 58 201910.21307/PM-2019.58.1.049 Search in Google Scholar

36. Gong Y., Li T., Yu C., Sun S.: Candida albicans heat shock proteins and hsps-associated signaling pathways as potential antifungal targets. Front. Cell. Infect. Microbiol. 7, 520 (2017) Gong Y. Li T. Yu C. Sun S. Candida albicans heat shock proteins and hsps-associated signaling pathways as potential antifungal targets Front. Cell. Infect. Microbiol. 7 520 201710.3389/fcimb.2017.00520574214229312897 Search in Google Scholar

37. Graminha M.A.S., Rocha E.M.F., Prade R.A., Martinez-Rossi N.M.: Terbinafine resistance mediated by salicylate 1-monooxygenase in Aspergillus nidulans. Antimicrob. Agents Chemother. 48, 3530–3535 (2004) Graminha M.A.S. Rocha E.M.F. Prade R.A. Martinez-Rossi N.M. Terbinafine resistance mediated by salicylate 1-monooxygenase in Aspergillus nidulans Antimicrob. Agents Chemother. 48 3530 3535 200410.1128/AAC.48.9.3530-3535.200451474015328121 Search in Google Scholar

38. Gupta A.K., Kohli Y.: In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity. Br. J. Dermatol. 149, 296–305 (2003) Gupta A.K. Kohli Y. In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity Br. J. Dermatol. 149 296 305 200310.1046/j.1365-2133.2003.05418.x12932235 Search in Google Scholar

39. Gupta C., Das S., Ramachandran V.G., Saha R., Bhattacharya S.N., Dar S.A., Atri D.: Possible role of trichophytin antigen in inducing impaired immunological clearance of fungus in onychomycosis. Mycopathologia, 181, 247–251 (2016) Gupta C. Das S. Ramachandran V.G. Saha R. Bhattacharya S.N. Dar S.A. Atri D. Possible role of trichophytin antigen in inducing impaired immunological clearance of fungus in onychomycosis Mycopathologia 181 247 251 201610.1007/s11046-015-9973-326614362 Search in Google Scholar

40. Harms N., Ras J., Reijnders W.N., van Spanning R.J., Stouthamer A.H.: S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification? J. Bacteriol. 178, 6296–6299 (1996) Harms N. Ras J. Reijnders W.N. van Spanning R.J. Stouthamer A.H. S-formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification? J. Bacteriol. 178 6296 6299 199610.1128/jb.178.21.6296-6299.19961785038892832 Search in Google Scholar

41. Havlickova B., Czaika V.A., Friedrich M.: Epidemiological trends in skin mycoses worldwide. Mycoses, 51, 2–15 (2008) Havlickova B. Czaika V.A. Friedrich M. Epidemiological trends in skin mycoses worldwide Mycoses 51 2 15 200810.1111/j.1439-0507.2008.01606.x18783559 Search in Google Scholar

42. Hayes B.M.E., Anderson M.A., Traven A., van der Weerden N.L., Bleackley M.R.: Activation of stress signalling pathways enhances tolerance of fungi to chemical fungicides and antifungal proteins. Cell. Mol. Life Sci. 71, 2651–2666 (2014) Hayes B.M.E. Anderson M.A. Traven A. van der Weerden N.L. Bleackley M.R. Activation of stress signalling pathways enhances tolerance of fungi to chemical fungicides and antifungal proteins Cell. Mol. Life Sci. 71 2651 2666 201410.1007/s00018-014-1573-824526056 Search in Google Scholar

43. Healey K.R., Perlin D.S.: Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata. J. fungi (Basel, Switzerland) 4, 105 (2018) Healey K.R. Perlin D.S. Fungal Resistance to Echinocandins and the MDR Phenomenon in Candida glabrata J. fungi (Basel, Switzerland) 4 105 201810.3390/jof4030105616276930200517 Search in Google Scholar

44. Holmes A.R., Cardno T.S., Strouse J.J., Ivnitski-Steele I., Keniya M.V, Lackovic K., Monk B.C., Sklar L.A., Cannon R.D.: Targeting efflux pumps to overcome antifungal drug resistance. Future Med. Chem. 8, 1485–1501 (2016) Holmes A.R. Cardno T.S. Strouse J.J. Ivnitski-Steele I. Keniya M.V Lackovic K. Monk B.C. Sklar L.A. Cannon R.D. Targeting efflux pumps to overcome antifungal drug resistance Future Med. Chem. 8 1485 1501 201610.4155/fmc-2016-0050582781927463566 Search in Google Scholar

45. Huang H., Yang M., Su Y., Qu L., Deng X.W.: Arabidopsis atypical kinases ABC1K1 and ABC1K3 act oppositely to cope with photodamage under red light. Mol. Plant 8, 1122–1124 (2015) Huang H. Yang M. Su Y. Qu L. Deng X.W. Arabidopsis atypical kinases ABC1K1 and ABC1K3 act oppositely to cope with photodamage under red light Mol. Plant 8 1122 1124 201510.1016/j.molp.2015.04.003570522125882344 Search in Google Scholar

46. Huang X., Yi J., Yin S., Li M., Ye C., Lai W., Chen J.: Trichophyton rubrum conidia modulate the expression and transport of Toll-like receptor 2 in HaCaT cell. Microb. Pathog. 83–84, 1–5 (2015) Huang X. Yi J. Yin S. Li M. Ye C. Lai W. Chen J. Trichophyton rubrum conidia modulate the expression and transport of Toll-like receptor 2 in HaCaT cell Microb. Pathog. 83 84 1 5 201510.1016/j.micpath.2015.04.00225871642 Search in Google Scholar

47. Jacob T.R., Peres N.T.A., Martins M.P., Lang E.A.S., Sanches P.R., Rossi A., Martinez-Rossi N.M.: Heat shock protein 90 (Hsp90) as a molecular target for the development of novel drugs against the dermatophyte Trichophyton rubrum. Front. Microbiol. 6, 1241 (2015) Jacob T.R. Peres N.T.A. Martins M.P. Lang E.A.S. Sanches P.R. Rossi A. Martinez-Rossi N.M. Heat shock protein 90 (Hsp90) as a molecular target for the development of novel drugs against the dermatophyte Trichophyton rubrum Front. Microbiol. 6 1241 201510.3389/fmicb.2015.01241463960926617583 Search in Google Scholar

48. Kano R., Hsiao Y.H., Han H.S., Chen C., Hasegawa A., Kamata H.: Resistance mechanism in a terbinafine-resistant strain of Microsporum canis. Mycopathologia, 183, 623–627 (2018) Kano R. Hsiao Y.H. Han H.S. Chen C. Hasegawa A. Kamata H. Resistance mechanism in a terbinafine-resistant strain of Microsporum canis Mycopathologia 183 623 627 201810.1007/s11046-018-0242-029340910 Search in Google Scholar

49. Khurana A., Sardana K., Chowdhary A.: Antifungal resistance in dermatophytes: Recent trends and therapeutic implications. Fungal Genet. Biol. 132, 103255 (2019) Khurana A. Sardana K. Chowdhary A. Antifungal resistance in dermatophytes: Recent trends and therapeutic implications Fungal Genet. Biol. 132 103255 201910.1016/j.fgb.2019.10325531330295 Search in Google Scholar

50. Kohler J.R., Hube B., Puccia R., Casadevall A., Perfect J.R.: Fungi that infect humans. Microbiol. Spectr. 5, (2017) Kohler J.R. Hube B. Puccia R. Casadevall A. Perfect J.R. Fungi that infect humans Microbiol. Spectr. 5 201710.1128/9781555819583.ch39 Search in Google Scholar

51. Łagowski D., Gnat S., Nowakiewicz A., Osińska M., Trościańczyk A., Zięba P.: In search of the source of dermatophytosis: Epidemiological analysis of Trichophyton verrucosum infection in llamas and the breeder (case report). Zoonoses Public Health 66, 982–989 (2019) Łagowski D. Gnat S. Nowakiewicz A. Osińska M. Trościańczyk A. Zięba P. In search of the source of dermatophytosis: Epidemiological analysis of Trichophyton verrucosum infection in llamas and the breeder (case report) Zoonoses Public Health 66 982 989 201910.1111/zph.1264831538413 Search in Google Scholar

52. Łagowski D., Gnat S., Nowakiewicz A., Osińska M., Zięba P.: The prevalence of symptomatic dermatophytoses in dogs and cats and the pathomechanism of dermatophyte infections. 58, 165–176 (2019) Łagowski D. Gnat S. Nowakiewicz A. Osińska M. Zięba P. The prevalence of symptomatic dermatophytoses in dogs and cats and the pathomechanism of dermatophyte infections 58 165 176 2019 Search in Google Scholar

53. Lamoth F., Juvvadi P.R., Fortwendel J.R., Steinbach W.J.: Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus. Eukaryot. Cell, Adv. Microbiol. 11, 1324–1332 (2012) Lamoth F. Juvvadi P.R. Fortwendel J.R. Steinbach W.J. Heat shock protein 90 is required for conidiation and cell wall integrity in Aspergillus fumigatus Eukaryot. Cell, Adv. Microbiol. 11 1324 1332 201210.1128/EC.00032-12348603222822234 Search in Google Scholar

54. Leach M.D., Budge S., Walker L., Munro C., Cowen L.E., Brown A.J.P.: Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast. PLoS Pathog. 8, e1003069 (2012) Leach M.D. Budge S. Walker L. Munro C. Cowen L.E. Brown A.J.P. Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast PLoS Pathog. 8 e1003069 201210.1371/journal.ppat.1003069353149823300438 Search in Google Scholar

55. Leach M.D., Klipp E., Cowen L.E., Brown A.J.P.: Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs. Nat. Rev. Microbiol. 10, 693–704 (2012) Leach M.D. Klipp E. Cowen L.E. Brown A.J.P. Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs Nat. Rev. Microbiol. 10 693 704 201210.1038/nrmicro2875366070222976491 Search in Google Scholar

56. Liu W., May G.S., Lionakis M.S., Lewis R.E., Kontoyiannis D.P.: Extra copies of the Aspergillus fumigatus squalene epoxidase gene confer resistance to terbinafine: genetic approach to studying gene dose-dependent resistance to antifungals in A. fumigatus. Antimicrob. Agents Chemother. 48, 2490–2496 (2004) Liu W. May G.S. Lionakis M.S. Lewis R.E. Kontoyiannis D.P. Extra copies of the Aspergillus fumigatus squalene epoxidase gene confer resistance to terbinafine: genetic approach to studying gene dose-dependent resistance to antifungals in A. fumigatus Antimicrob. Agents Chemother. 48 2490 2496 200410.1128/AAC.48.7.2490-2496.200443421815215099 Search in Google Scholar

57. Martinez-Rossi N.M., Peres N.T.A., Rossi A.: Pathogenesis of dermatophytosis: sensing the host tissue. Mycopathologia, 182, 215–227 (2017) Martinez-Rossi N.M. Peres N.T.A. Rossi A. Pathogenesis of dermatophytosis: sensing the host tissue Mycopathologia 182 215 227 201710.1007/s11046-016-0057-927590362 Search in Google Scholar

58. Martinez-Rossi N.M., Bitencourt T.A., Peres N.T.A., Lang E.A.S., Gomes E. V, Quaresemin N.R., Martins M.P., Lopes L., Rossi A.: Dermatophyte resistance to antifungal drugs: mechanisms and prospectus. Front. Microbiol. 9, 1108 (2018) Martinez-Rossi N.M. Bitencourt T.A. Peres N.T.A. Lang E.A.S. Gomes E. V Quaresemin N.R. Martins M.P. Lopes L. Rossi A. Dermatophyte resistance to antifungal drugs: mechanisms and prospectus Front. Microbiol. 9 1108 201810.3389/fmicb.2018.01108598690029896175 Search in Google Scholar

59. Martinez-Rossi N.M., Jacob T.R., Sanches P.R., Peres N.T.A., Lang E.A.S., Martins M.P., Rossi A.: Heat shock proteins in dermatophytes: current advances and perspectives. Curr. Genomics 17, 99–111 (2016) Martinez-Rossi N.M. Jacob T.R. Sanches P.R. Peres N.T.A. Lang E.A.S. Martins M.P. Rossi A. Heat shock proteins in dermatophytes: current advances and perspectives Curr. Genomics 17 99 111 201610.2174/1389202917666151116212437486483827226766 Search in Google Scholar

60. Martinez-Rossi N.M., Peres N.T.A., Rossi A.: Antifungal resistance mechanisms in dermatophytes. Mycopathologia, 166, 369–383 (2008) Martinez-Rossi N.M. Peres N.T.A. Rossi A. Antifungal resistance mechanisms in dermatophytes Mycopathologia 166 369 383 200810.1007/s11046-008-9110-718478356 Search in Google Scholar

61. Martins M.P., Franceschini A.C.C., Jacob T.R., Rossi A., Martinez-Rossi N.M.: Compensatory expression of multidrug-resistance genes encoding ABC transporters in dermatophytes. J. Med. Microbiol. 65, 605–610 (2016) Martins M.P. Franceschini A.C.C. Jacob T.R. Rossi A. Martinez-Rossi N.M. Compensatory expression of multidrug-resistance genes encoding ABC transporters in dermatophytes J. Med. Microbiol. 65 605 610 201610.1099/jmm.0.00026827121717 Search in Google Scholar

62. Mendes N.S., Bitencourt T.A., Sanches P.R., Silva-Rocha R., Martinez-Rossi N.M., Rossi A.: Transcriptome-wide survey of gene expression changes and alternative splicing in Trichophyton rubrum in response to undecanoic acid. Sci. Rep. 8, 2520 (2018) Mendes N.S. Bitencourt T.A. Sanches P.R. Silva-Rocha R. Martinez-Rossi N.M. Rossi A. Transcriptome-wide survey of gene expression changes and alternative splicing in Trichophyton rubrum in response to undecanoic acid Sci. Rep. 8 2520 201810.1038/s41598-018-20738-x580273429410524 Search in Google Scholar

63. Monod M.: Secreted proteases from dermatophytes. Mycopathologia, 166, 285–294 (2008) Monod M. Secreted proteases from dermatophytes Mycopathologia 166 285 294 200810.1007/s11046-008-9105-418478360 Search in Google Scholar

64. Morio F., Loge C., Besse B., Hennequin C., Le Pape P.: Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature. Diagn. Microbiol. Infect. Dis. 66, 373–384 (2010) Morio F. Loge C. Besse B. Hennequin C. Le Pape P. Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature Diagn. Microbiol. Infect. Dis. 66 373 384 201010.1016/j.diagmicrobio.2009.11.00620226328 Search in Google Scholar

65. Nenoff P., Verma S., Vasani R., Burmester A., Hipler U.C., Wittig F., Krüger C., Nenoff K., Wiegand C., Saraswat A., Madhu R., Panda S., Das A., Kura M., Jain A., i wsp.: The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes-A molecular study. Mycoses, (2018) Nenoff P. Verma S. Vasani R. Burmester A. Hipler U.C. Wittig F. Krüger C. Nenoff K. Wiegand C. Saraswat A. Madhu R. Panda S. Das A. Kura M. Jain A. i wsp.: The current Indian epidemic of superficial dermatophytosis due to Trichophyton mentagrophytes-A molecular study Mycoses 201810.1111/myc.1287830561859 Search in Google Scholar

66. Noguchi K., Fukazawa H., Murakami Y., Uehara Y.: Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses. J. Biol. Chem. 277, 39655–39665 (2002) Noguchi K. Fukazawa H. Murakami Y. Uehara Y. Nek11, a new member of the NIMA family of kinases, involved in DNA replication and genotoxic stress responses J. Biol. Chem. 277 39655 39665 200210.1074/jbc.M20459920012154088 Search in Google Scholar

67. Osborne C.S., Leitner I., Favre B., Ryder N.S.: Amino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine. Antimicrob. Agents Chemother. 49, 2840–2844 (2005) Osborne C.S. Leitner I. Favre B. Ryder N.S. Amino acid substitution in Trichophyton rubrum squalene epoxidase associated with resistance to terbinafine Antimicrob. Agents Chemother. 49 2840 2844 200510.1128/AAC.49.7.2840-2844.2005116863815980358 Search in Google Scholar

68. Paiao F.G., Segato F., Cursino-Santos J.R., Peres N.T.A., Martinez-Rossi N.M.: Analysis of Trichophyton rubrum gene expression in response to cytotoxic drugs. FEMS Microbiol. Lett. 271, 180–186 (2007) Paiao F.G. Segato F. Cursino-Santos J.R. Peres N.T.A. Martinez-Rossi N.M. Analysis of Trichophyton rubrum gene expression in response to cytotoxic drugs FEMS Microbiol. Lett. 271 180 186 200710.1111/j.1574-6968.2007.00710.x17425668 Search in Google Scholar

69. Pearce L.R., Komander D., Alessi D.R.: The nuts and bolts of AGC protein kinases. Nat. Rev. Mol. Cell Biol. 11, 9–22 (2010) Pearce L.R. Komander D. Alessi D.R. The nuts and bolts of AGC protein kinases Nat. Rev. Mol. Cell Biol. 11 9 22 201010.1038/nrm282220027184 Search in Google Scholar

70. Peman J., Canton E., Espinel-Ingroff A.: Antifungal drug resistance mechanisms. Expert Rev. Anti. Infect. Ther. 7, 453–460 (2009) Peman J. Canton E. Espinel-Ingroff A. Antifungal drug resistance mechanisms Expert Rev. Anti. Infect. Ther. 7 453 460 200910.1586/eri.09.1819400764 Search in Google Scholar

71. Peres N.T., Sanches P.R., Falco J.P., Silveira H.C., Paião F.G., Maranhão F.C., Gras D.E., Segato F., Cazzaniga R.A., Mazucato M., Cursino-Santos J.R., Aquino-Ferreira R., Rossi A., Martinez-Rossi N.M.: Transcriptional profiling reveals the expression of novel genes in response to various stimuli in the human dermatophyte Trichophyton rubrum. BMC Microbiol. 10, 39 (2010) Peres N.T. Sanches P.R. Falco J.P. Silveira H.C. Paião F.G. Maranhão F.C. Gras D.E. Segato F. Cazzaniga R.A. Mazucato M. Cursino-Santos J.R. Aquino-Ferreira R. Rossi A. Martinez-Rossi N.M. Transcriptional profiling reveals the expression of novel genes in response to various stimuli in the human dermatophyte Trichophyton rubrum BMC Microbiol. 10 39 201010.1186/1471-2180-10-39283188320144196 Search in Google Scholar

72. Peres N.T. de A., Maranhao F.C.A., Rossi A., Martinez-Rossi N.M.: Dermatophytes: host-pathogen interaction and antifungal resistance. An. Bras. Dermatol. 85, 657–667 (2010) Peres N.T. de A. Maranhao F.C.A. Rossi A. Martinez-Rossi N.M. Dermatophytes: host-pathogen interaction and antifungal resistance An. Bras. Dermatol. 85 657 667 201010.1590/S0365-0596201000050000921152790 Search in Google Scholar

73. Persinoti G.F., de Aguiar Peres N.T., Jacob T.R., Rossi A., Vencio R.Z., Martinez-Rossi N.M.: RNA-sequencing analysis of Trichophyton rubrum transcriptome in response to sublethal doses of acriflavine. BMC Genomics, 15 Suppl 7, S1 (2014) Persinoti G.F. de Aguiar Peres N.T. Jacob T.R. Rossi A. Vencio R.Z. Martinez-Rossi N.M. RNA-sequencing analysis of Trichophyton rubrum transcriptome in response to sublethal doses of acriflavine BMC Genomics 15 Suppl 7, S1 201410.1186/1471-2164-15-S7-S1424328825573029 Search in Google Scholar

74. Putman M., van Veen H.W., Konings W.N.: Molecular properties of bacterial multidrug transporters. Microbiol. Mol. Biol. Rev. 64, 672–693 (2000) Putman M. van Veen H.W. Konings W.N. Molecular properties of bacterial multidrug transporters Microbiol. Mol. Biol. Rev. 64 672 693 200010.1128/MMBR.64.4.672-693.20009900911104814 Search in Google Scholar

75. Robbins N., Caplan T., Cowen L.E.: Molecular Evolution of Antifungal Drug Resistance. Annu. Rev. Microbiol. 71, 753–775 (2017) Robbins N. Caplan T. Cowen L.E. Molecular Evolution of Antifungal Drug Resistance Annu. Rev. Microbiol. 71 753 775 201710.1146/annurev-micro-030117-02034528886681 Search in Google Scholar

76. Rocha E.M.F., Gardiner R.E., Park S., Martinez-Rossi N.M., Perlin D.S.: A Phe389Leu substitution in ergA confers terbinafine resistance in Aspergillus fumigatus. Antimicrob. Agents Chemother. 50, 2533–2536 (2006) Rocha E.M.F. Gardiner R.E. Park S. Martinez-Rossi N.M. Perlin D.S. A Phe389Leu substitution in ergA confers terbinafine resistance in Aspergillus fumigatus Antimicrob. Agents Chemother. 50 2533 2536 200610.1128/AAC.00187-06148977516801438 Search in Google Scholar

77. Rooker S., Guillemaud T., Berge J., Pasteur N., Raymond M.: Coamplification of esterase A and B genes as a single unit in Culex pipiens mosquitoes. Heredity (Edinb). 77 (Pt 5), 555–561 (1996) Rooker S. Guillemaud T. Berge J. Pasteur N. Raymond M. Coamplification of esterase A and B genes as a single unit in Culex pipiens mosquitoes Heredity (Edinb). 77 (Pt 5), 555 561 1996 Search in Google Scholar

78. Sagatova A.A., Keniya M. V, Wilson R.K., Sabherwal M., Tyndall J.D.A., Monk B.C.: Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14alpha-demethylase. Sci. Rep. 6, 26213 (2016) Sagatova A.A. Keniya M. V Wilson R.K. Sabherwal M. Tyndall J.D.A. Monk B.C. Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14alpha-demethylase Sci. Rep. 6 26213 201610.1038/srep26213487055627188873 Search in Google Scholar

79. Sanglard D.: Emerging threats in antifungal-resistant fungal pathogens. Front. Med. 3, 11 (2016) Sanglard D. Emerging threats in antifungal-resistant fungal pathogens Front. Med. 3 11 201610.3389/fmed.2016.00011479136927014694 Search in Google Scholar

80. Sanglard D., Coste A., Ferrari S.: Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation. FEMS Yeast Res. 9, 1029–1050 (2009) Sanglard D. Coste A. Ferrari S. Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation FEMS Yeast Res. 9 1029 1050 200910.1111/j.1567-1364.2009.00578.x19799636 Search in Google Scholar

81. Santos H.L., Lang E.A.S., Segato F., Rossi A., Martinez-Rossi N.M.: Terbinafine resistance conferred by multiple copies of the salicylate 1-monooxygenase gene in Trichophyton rubrum. Med. Mycol. 56, 378–381 (2018) Santos H.L. Lang E.A.S. Segato F. Rossi A. Martinez-Rossi N.M. Terbinafine resistance conferred by multiple copies of the salicylate 1-monooxygenase gene in Trichophyton rubrum Med. Mycol. 56 378 381 2018 Search in Google Scholar

82. Santos M.A., Jimenez A., Revuelta J.L.: Molecular characterization of FMN1, the structural gene for the monofunctional flavokinase of Saccharomyces cerevisiae. J. Biol. Chem. 275, 28618–28624 (2000) Santos M.A. Jimenez A. Revuelta J.L. Molecular characterization of FMN1, the structural gene for the monofunctional flavokinase of Saccharomyces cerevisiae J. Biol. Chem. 275 28618 28624 200010.1074/jbc.M00462120010887197 Search in Google Scholar

83. Schopf F.H., Biebl M.M., Buchner J.: The HSP90 chaperone machinery. Nat. Rev. Mol. Cell Biol. 18, 345–360 (2017) Schopf F.H. Biebl M.M. Buchner J. The HSP90 chaperone machinery Nat. Rev. Mol. Cell Biol. 18 345 360 201710.1038/nrm.2017.2028429788 Search in Google Scholar

84. Segato F., Nozawa S.R., Rossi A., Martinez-Rossi N.M.: Overexpression of genes coding for proline oxidase, riboflavin kinase, cytochrome c oxidase and an MFS transporter induced by acriflavin in Trichophyton rubrum. Med. Mycol. 46, 135–139 (2008) Segato F. Nozawa S.R. Rossi A. Martinez-Rossi N.M. Overexpression of genes coding for proline oxidase, riboflavin kinase, cytochrome c oxidase and an MFS transporter induced by acriflavin in Trichophyton rubrum Med. Mycol. 46 135 139 200810.1080/1369378070174238118324492 Search in Google Scholar

85. Selmecki A., Forche A., Berman J.: Genomic plasticity of the human fungal pathogen Candida albicans. Eukaryot. Cell, 9, 991–1008 (2010) Selmecki A. Forche A. Berman J. Genomic plasticity of the human fungal pathogen Candida albicans Eukaryot. Cell 9 991 1008 201010.1128/EC.00060-10290167420495058 Search in Google Scholar

86. Sharma M., Prasad R.: The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans. Antimicrob. Agents Chemother. 55, 4834–4843 (2011) Sharma M. Prasad R. The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans Antimicrob. Agents Chemother. 55 4834 4843 201110.1128/AAC.00344-11318695921768514 Search in Google Scholar

87. Singh S.D., Robbins N., Zaas A.K., Schell W.A., Perfect J.R., Cowen L.E.: Hsp90 Governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. PLOS Pathog. 5, e1000532 (2009) Singh S.D. Robbins N. Zaas A.K. Schell W.A. Perfect J.R. Cowen L.E. Hsp90 Governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin PLOS Pathog. 5 e1000532 200910.1371/journal.ppat.1000532271206919649312 Search in Google Scholar

88. Sionov E., Lee H., Chang Y.C., Kwon-Chung K.J.: Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes. PLoS Pathog. 6, e1000848 (2010) Sionov E. Lee H. Chang Y.C. Kwon-Chung K.J. Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes PLoS Pathog. 6 e1000848 201010.1371/journal.ppat.1000848284856020368972 Search in Google Scholar

89. Suwunnakorn S., Wakabayashi H., Kordalewska M., Perlin D.S., Rustchenko E.: FKS2 and FKS3 genes of opportunistic human pathogen Candida albicans influence echinocandin susceptibility. Antimicrob. Agents Chemother. 62, (2018) Suwunnakorn S. Wakabayashi H. Kordalewska M. Perlin D.S. Rustchenko E. FKS2 and FKS3 genes of opportunistic human pathogen Candida albicans influence echinocandin susceptibility Antimicrob. Agents Chemother. 62 201810.1128/AAC.02299-17591391629358288 Search in Google Scholar

90. Tiwari S., Thakur R., Shankar J.: Role of heat-shock proteins in cellular function and in the biology of fungi. Biotechnol. Res. Int. 2015, 132635 (2015) Tiwari S. Thakur R. Shankar J. Role of heat-shock proteins in cellular function and in the biology of fungi Biotechnol. Res. Int. 2015 132635 201510.1155/2015/132635473600126881084 Search in Google Scholar

91. Wadler C., Cronan J.E.: Dephospho-CoA kinase provides a rapid and sensitive radiochemical assay for coenzyme A and its thioesters. Anal. Biochem. 368, 17–23 (2007) Wadler C. Cronan J.E. Dephospho-CoA kinase provides a rapid and sensitive radiochemical assay for coenzyme A and its thioesters Anal. Biochem. 368 17 23 200710.1016/j.ab.2007.05.031266942917603993 Search in Google Scholar

92. Widmann C., Gibson S., Jarpe M.B., Johnson G.L.: Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol. Rev. 79, 143–180 (1999) Widmann C. Gibson S. Jarpe M.B. Johnson G.L. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human Physiol. Rev. 79 143 180 199910.1152/physrev.1999.79.1.1439922370 Search in Google Scholar

93. Yamada T., Maeda M., Alshahni M.M., Tanaka R., Yaguchi T., Bontems O., Salamin K., Fratti M., Monod M.: Terbinafine resistance of Trichophyton clinical isolates caused by specific point mutations in the squalene epoxidase gene. Antimicrob. Agents Chemother. 61, (2017) Yamada T. Maeda M. Alshahni M.M. Tanaka R. Yaguchi T. Bontems O. Salamin K. Fratti M. Monod M. Terbinafine resistance of Trichophyton clinical isolates caused by specific point mutations in the squalene epoxidase gene Antimicrob. Agents Chemother. 61 201710.1128/AAC.00115-17548765828416557 Search in Google Scholar

94. Yibmantasiri P., Bircham P.W., Maass D.R., Bellows D.S., Atkinson P.H.: Networks of genes modulating the pleiotropic drug response in Saccharomyces cerevisiae. Mol. Biosyst. 10, 128–137 (2014) Yibmantasiri P. Bircham P.W. Maass D.R. Bellows D.S. Atkinson P.H. Networks of genes modulating the pleiotropic drug response in Saccharomyces cerevisiae Mol. Biosyst. 10 128 137 201410.1039/C3MB70351G Search in Google Scholar

95. Yu L., Zhang W., Liu T., Wang X., Peng J., Li S., Jin Q.: Global gene expression of Trichophyton rubrum in response to PH11B, a novel fatty acid synthase inhibitor. J. Appl. Microbiol. 103, 2346–2352 (2007) Yu L. Zhang W. Liu T. Wang X. Peng J. Li S. Jin Q. Global gene expression of Trichophyton rubrum in response to PH11B, a novel fatty acid synthase inhibitor J. Appl. Microbiol. 103 2346 2352 200710.1111/j.1365-2672.2007.03521.x18045420 Search in Google Scholar

96. Yu L., Zhang W., Wang L., Yang J., Liu T., Peng J., Leng W., Chen L., Li R., Jin Q.: Transcriptional profiles of the response to ketoconazole and amphotericin B in Trichophyton rubrum. Antimicrob. Agents Chemother. 51, 144–153 (2007) Yu L. Zhang W. Wang L. Yang J. Liu T. Peng J. Leng W. Chen L. Li R. Jin Q. Transcriptional profiles of the response to ketoconazole and amphotericin B in Trichophyton rubrum Antimicrob. Agents Chemother. 51 144 153 200710.1128/AAC.00755-06179765217060531 Search in Google Scholar

97. Zhang W., Yu L., Leng W., Wang X., Wang L., Deng X., Yang J., Liu T., Peng J., Wang J., Li S., Jin Q.: cDNA microarray analysis of the expression profiles of Trichophyton rubrum in response to novel synthetic fatty acid synthase inhibitor PHS11A. Fungal Genet. Biol. 44, 1252–1261 (2007) Zhang W. Yu L. Leng W. Wang X. Wang L. Deng X. Yang J. Liu T. Peng J. Wang J. Li S. Jin Q. cDNA microarray analysis of the expression profiles of Trichophyton rubrum in response to novel synthetic fatty acid synthase inhibitor PHS11A Fungal Genet. Biol. 44 1252 1261 200710.1016/j.fgb.2007.03.00217442600 Search in Google Scholar

98. Zonios D.I., Bennett J.E.: Update on azole antifungals. Semin. Respir. Crit. Care Med. 29, 198–210 (2008) Zonios D.I. Bennett J.E. Update on azole antifungals Semin. Respir. Crit. Care Med. 29 198 210 200810.1055/s-2008-106385818366001 Search in Google Scholar