Article Category: article
Published Online: Jun 10, 2019
Page range: 7 - 18
Received: Jun 01, 2018
Accepted: Nov 01, 2018
DOI: https://doi.org/10.21307/PM-2019.58.1.007
© 2019 Aleksandra Góralczyk-Bińkowska et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Multicopper oxidases (MCOs) are a large family of blue copper proteins which contain from one to six copper atoms per molecule. Their catalytic centre consists of three domains which involve type I Cu, type II Cu and a pair of type III Cu’s. They include laccases, ferroxidases, ascorbate oxidase, bilirubin oxidase, laccase-like multicopper oxidases. MCOs are capable of one-electron oxidizing of aromatic as well as non-aromatic compounds with a concomitant four-electron reduction of molecular oxygen to water. These properties make them a valuable tool in various industries (e.g. food, textile, pharmaceutical) medicine or environment protection.
1. Introduction. 2. Multicopper oxidases – classification, structure and properties. 3. Identification methods of MCOs. 4. Laccases vs. others MCOs. 5. Application of multicopper oxidases. 6. Summary