<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Inhalation is one of the routes of drug administration used in therapy. Medicines are dispersed via an aerosol spray, mist, powder or vapour that patients breathe into their airways. Depending on the intrapulmonary behaviour of each molecule of the inhaled agent, the prevailing effect obtained may be local or general. Inhaled therapy, due to its local effect, is a cornerstone of obstructive pulmonary diseases like asthma and chronic obstructive pulmonary disease (COPD), while the general effects of vaporised medical cannabis support its use in other indications (e.g. epilepsy, insomnia, spastic pain). Regardless of the purpose of use, an inhaled drug passes through the oropharynx and a major portion of its dose remains there. This paper focuses on the impact of inhaled therapy on the oral cavity, highlighting the issues important for dental practitioners. The most common indications for inhaled therapy are presented together with the devices used for this route of administration and the drugs employed in outpatient care. Particular attention is paid to oral side effects of inhaled medicines and their pathophysiology. The advisable measures for dental care of patients using inhaled therapy are presented.</p>
</abstract>

Inhalation is one of the routes of drug administration used in therapy. Medicines are dispersed via an aerosol spray, mist, powder or vapour that patients breathe into their airways. Depending on the intrapulmonary behaviour of each molecule of the inhaled agent, the prevailing effect obtained may be local or general. Inhaled therapy, due to its local effect, is a cornerstone of obstructive pulmonary diseases like asthma and chronic obstructive pulmonary disease (COPD), while the general effects of vaporised medical cannabis support its use in other indications (e.g. epilepsy, insomnia, spastic pain). Regardless of the purpose of use, an inhaled drug passes through the oropharynx and a major portion of its dose remains there. This paper focuses on the impact of inhaled therapy on the oral cavity, highlighting the issues important for dental practitioners. The most common indications for inhaled therapy are presented together with the devices used for this route of administration and the drugs employed in outpatient care. Particular attention is paid to oral side effects of inhaled medicines and their pathophysiology. The advisable measures for dental care of patients using inhaled therapy are presented.

The dental considerations of outpatient inhalation therapy

Department of Pharmacology, Division of Clinical Pharmacology

Pomeranian Journal of Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"The dental considerations of outpatient inhalation therapy"}

Inhalation is one of the routes of drug administration used in therapy. Medicines are dispersed via an aerosol spray, mist, powder or vapour that patients...

The dental considerations of outpatient inhalation therapy

Published Online: Oct 08, 2023

Page range: 52 - 59

DOI: https://doi.org/10.21164/pomjlifesci.941

Keywords
inhaled therapy, asthma, chronic obstructive pulmonary disease (COPD), medical cannabis, oral health

© 2023 Marcin Pasternak, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The dental considerations of outpatient inhalation therapy

Published Online: Oct 08, 2023

Page range: 52 - 59

DOI: https://doi.org/10.21164/pomjlifesci.941

Keywordsinhaled therapy, asthma, chronic obstructive pulmonary disease (COPD), medical cannabis, oral health

© 2023 Marcin Pasternak, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
inhaled therapy, asthma, chronic obstructive pulmonary disease (COPD), medical cannabis, oral health