<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Tramadol is the most widely used analgesic in the world. Indications for the general administration of tramadol in dentistry and oral surgery are restricted to cases with moderate to severe pain. However, new evidence supports the peripheral use of this well-known drug. The unique properties of this atypical opioid, including its impact on neuronal conduction, attenuation of inflammation, and antimicrobial effects, together with its possible beneficial influence on the wound healing process, have been observed after local administration in human and animal research. The paper focuses on the local administration of tramadol within orofacial tissues, with particular consideration given to its possible use in dentistry.</p>
</abstract>

Tramadol is the most widely used analgesic in the world. Indications for the general administration of tramadol in dentistry and oral surgery are restricted to cases with moderate to severe pain. However, new evidence supports the peripheral use of this well-known drug. The unique properties of this atypical opioid, including its impact on neuronal conduction, attenuation of inflammation, and antimicrobial effects, together with its possible beneficial influence on the wound healing process, have been observed after local administration in human and animal research. The paper focuses on the local administration of tramadol within orofacial tissues, with particular consideration given to its possible use in dentistry.

Does tramadol have a place in the dental armamentarium? An atypical opioid in dental practice from the pharmacological perspective – Part II. Local tramadol administration within orofacial tissues

Department of Pharmacology, Division of Clinical Pharmacology

Pomeranian Journal of Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Tramadol is the most widely used analgesic in the world. Indications for the general administration of tramadol in dentistry and oral surgery are restricted to...

Does tramadol have a place in the dental armamentarium? An atypical opioid in dental practice from the pharmacological perspective – Part II. Local tramadol administration within orofacial tissues

Published Online: Jul 16, 2023

Page range: 28 - 32

DOI: https://doi.org/10.21164/pomjlifesci.930

Keywords
tramadol, pain management, dentistry, oral surgery

© 2023 Marcin Pasternak, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Does tramadol have a place in the dental armamentarium? An atypical opioid in dental practice from the pharmacological perspective – Part II. Local tramadol administration within orofacial tissues

Published Online: Jul 16, 2023

Page range: 28 - 32

DOI: https://doi.org/10.21164/pomjlifesci.930

Keywordstramadol, pain management, dentistry, oral surgery

© 2023 Marcin Pasternak, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
tramadol, pain management, dentistry, oral surgery