<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Psoriasis is an autoimmune disease resulting in para- and hyperkeratosis of the epidermis, which is manifested by specific skin lesions. It affects approx. 2% of the European and the US populations; however, it is less common in Asia and Africa. Psoriatic patients show certain changes in blood components due to chronic inflammation, and the concentrations of some micronutrients may differ from those observed in healthy individuals. In the literature, there are many studies analyzing the concentrations of various elements in the course of the disease. Our review summarizes the association of the following microelements with psoriasis: Cu, Se, Fe, Zn, Ni, Cr, Cd, and As. In the case of Cu, all researchers report an increase in its blood concentration, but the results concerning other microelements are inconclusive. The discrepancies may stem from differences between the studied populations, environmental conditions, and anthropogenic pollution. However, the role of trace elements is rather marginal in comparison to the well-documented factors that are the focal points for modern psoriasis therapy.</p>
</abstract>

Psoriasis is an autoimmune disease resulting in para- and hyperkeratosis of the epidermis, which is manifested by specific skin lesions. It affects approx. 2% of the European and the US populations; however, it is less common in Asia and Africa. Psoriatic patients show certain changes in blood components due to chronic inflammation, and the concentrations of some micronutrients may differ from those observed in healthy individuals. In the literature, there are many studies analyzing the concentrations of various elements in the course of the disease. Our review summarizes the association of the following microelements with psoriasis: Cu, Se, Fe, Zn, Ni, Cr, Cd, and As. In the case of Cu, all researchers report an increase in its blood concentration, but the results concerning other microelements are inconclusive. The discrepancies may stem from differences between the studied populations, environmental conditions, and anthropogenic pollution. However, the role of trace elements is rather marginal in comparison to the well-documented factors that are the focal points for modern psoriasis therapy.

Trace elements in blood compartments in psoriatic patients and their impact on the course of the disease – literature review

Pomeranian Medical University in Szczecin

Hospital No. 1, Pediatric, Oncology and Child Immunology Department

Department of Gastroenterology and Internal Medicine

Hospital No. 1, Pediatric Emergency Department

University of Warmia and Mazury in Olsztyn

Pomeranian Journal of Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Psoriasis is an autoimmune disease resulting in para- and hyperkeratosis of the epidermis, which is manifested by specific skin lesions. It affects approx. 2%...

Trace elements in blood compartments in psoriatic patients and their impact on the course of the disease – literature review

Published Online: Jul 16, 2023

Page range: 40 - 44

DOI: https://doi.org/10.21164/pomjlifesci.929

Keywords
trace elements, psoriasis, psoriatic patients, microelements in psoriasis, selenium and zinc in psoriasis

© 2023 Bartłomiej Pala et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Trace elements in blood compartments in psoriatic patients and their impact on the course of the disease – literature review

Published Online: Jul 16, 2023

Page range: 40 - 44

DOI: https://doi.org/10.21164/pomjlifesci.929

Keywordstrace elements, psoriasis, psoriatic patients, microelements in psoriasis, selenium and zinc in psoriasis

© 2023 Bartłomiej Pala et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
trace elements, psoriasis, psoriatic patients, microelements in psoriasis, selenium and zinc in psoriasis