<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction</bold>: Glioma and meningioma, the 2 most common primary tumours of the optic nerve and optic nerve sheath are usually benign, slow-growing tumours.The aim of the paper is to provide an overview of clinical, histo-logical and radiological features of the most common primary tumours of the optic nerve and optic nerve sheath, as well as to discuss available treatment options.<bold>Materials and methods</bold>: A literature review was performed based on articles discussing optic nerve glioma and meningioma of the optic nerve sheath.<bold>Results</bold>: Glioma is the most common primary tumour of the optic nerve. In 90% of the patients, the onset is within the first 2 decades of life. Meningioma is the most common primary tumour of the optic nerve sheath. In 95% of the sufferers, the onset is in adulthood. Although rare in the general population, primary tumours of the optic nerve and its sheath are seen more often in patients with neurofibromatosis (NF). Glioma moreoften affect patients with NF1, whereas meningiomas more often affect those with NF2. Unlike in children, optic nerve glioma in adults can be malignant. On the other hand, optic nerve sheath meningioma tends to be more malignant in children rather than in adults. The symptoms of optic nerve glioma and optic nerve sheath meningioma can be similar, including vision impairment and proptosis. The diagnosis is based on orbital imaging with magnetic resonance image (MRI) or computed tomography (CT). The management most often involves clinical observation. Surgery, radiation therapy or chemotherapy are only used in selected cases with the risk of optic chiasm or fellow optic nerve involvement.<bold>Conclusions</bold>: Primary tumours of the optic nerve and optic nerve sheath are rare. Consolidated knowledge and improved understanding can aide early diagnosis and proper management of such cases.</abstract>

Introduction: Glioma and meningioma, the 2 most common primary tumours of the optic nerve and optic nerve sheath are usually benign, slow-growing tumours.The aim of the paper is to provide an overview of clinical, histo-logical and radiological features of the most common primary tumours of the optic nerve and optic nerve sheath, as well as to discuss available treatment options.Materials and methods: A literature review was performed based on articles discussing optic nerve glioma and meningioma of the optic nerve sheath.Results: Glioma is the most common primary tumour of the optic nerve. In 90% of the patients, the onset is within the first 2 decades of life. Meningioma is the most common primary tumour of the optic nerve sheath. In 95% of the sufferers, the onset is in adulthood. Although rare in the general population, primary tumours of the optic nerve and its sheath are seen more often in patients with neurofibromatosis (NF). Glioma moreoften affect patients with NF1, whereas meningiomas more often affect those with NF2. Unlike in children, optic nerve glioma in adults can be malignant. On the other hand, optic nerve sheath meningioma tends to be more malignant in children rather than in adults. The symptoms of optic nerve glioma and optic nerve sheath meningioma can be similar, including vision impairment and proptosis. The diagnosis is based on orbital imaging with magnetic resonance image (MRI) or computed tomography (CT). The management most often involves clinical observation. Surgery, radiation therapy or chemotherapy are only used in selected cases with the risk of optic chiasm or fellow optic nerve involvement.Conclusions: Primary tumours of the optic nerve and optic nerve sheath are rare. Consolidated knowledge and improved understanding can aide early diagnosis and proper management of such cases.

Primary tumours of the optic nerve and the optic nerve sheath

Pomeranian Medical University in Szczecin

Pomeranian Journal of Life Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Primary tumours of the optic nerve and the optic nerve sheath"}

Introduction: Glioma and meningioma, the 2 most common primary tumours of the optic nerve and optic nerve sheath are usually benign, slow-growing tumours.The...

Primary tumours of the optic nerve and the optic nerve sheath

Published Online: Sep 24, 2019

Page range: 41 - 44

DOI: https://doi.org/10.21164/pomjlifesci.601

Keywords
optic nerve glioma, optic nerve sheath meningioma

© 2020 Kamila Krasodomska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Primary tumours of the optic nerve and the optic nerve sheath

Published Online: Sep 24, 2019

Page range: 41 - 44

DOI: https://doi.org/10.21164/pomjlifesci.601

Keywordsoptic nerve glioma, optic nerve sheath meningioma

© 2020 Kamila Krasodomska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
optic nerve glioma, optic nerve sheath meningioma