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Axillary adenopathy after COVID-19 vaccine in patients undergoing breast ultrasound

Sara De Giorgis
Sara De Giorgis
, 
Alessandro Garlaschi
Alessandro Garlaschi
, 
Nicole Brunetti
Nicole Brunetti
, 
Simona Tosto
Simona Tosto
, 
Giuseppe Rescinito
Giuseppe Rescinito
, 
Francesco Monetti
Francesco Monetti
, 
Claudio Oddone
Claudio Oddone
, 
Barbara Massa
Barbara Massa
, 
Francesca Pitto
Francesca Pitto
, 
Massimo Calabrese
Massimo Calabrese
 and 
Alberto Stefano Tagliafico
Alberto Stefano Tagliafico
   | Dec 15, 2021
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Article Category: research-article
Published Online: Dec 15, 2021
Page range: 361 - 364
Received: Jun 22, 2021
Accepted: Nov 05, 2021
DOI: https://doi.org/10.15557/jou.2021.0060
Keywords
© 2021 Polish Ultrasound Society. Published by Medical Communications Sp. z o.o.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Fig. 1.

Example of vaccine-associated adenopathy in a 66-year-old female patient undergoing breast ultrasound for routine breast imaging with history of breast cancer in the left breast. A. US in the left shoulder showing left axillary adenopathy (22 mm) with fatty hilum and thickened cortex. B. A core biopsy was performed. C. The histology was negative for lymph node malignancy (normal lymphocytes and histiocytes in hematoxylin-eosin staining)
Example of vaccine-associated adenopathy in a 66-year-old female patient undergoing breast ultrasound for routine breast imaging with history of breast cancer in the left breast. A. US in the left shoulder showing left axillary adenopathy (22 mm) with fatty hilum and thickened cortex. B. A core biopsy was performed. C. The histology was negative for lymph node malignancy (normal lymphocytes and histiocytes in hematoxylin-eosin staining)

Fig. 2.

Example of vaccine-associated adenopathy in a 29-year-old female undergoing breast ultrasound for routine breast imaging due to increased breast density. A. US in the left shoulder showing asymmetric left axillary adenopathy (18 mm) with preserved fatty hilum but irregular cortex. B. Four-week follow-up: axillary sonography of the same patient demonstrates decreased size (13 cm) and some residual cortical thickening. C. Eight-week follow-up: axillary ultrasound shows normal sized lymph node
Example of vaccine-associated adenopathy in a 29-year-old female undergoing breast ultrasound for routine breast imaging due to increased breast density. A. US in the left shoulder showing asymmetric left axillary adenopathy (18 mm) with preserved fatty hilum but irregular cortex. B. Four-week follow-up: axillary sonography of the same patient demonstrates decreased size (13 cm) and some residual cortical thickening. C. Eight-week follow-up: axillary ultrasound shows normal sized lymph node

Breast ultrasound features of axillary lymph nodes

Number of patient Patient age (years) Previous breast cancer US feature axillary lymph node: axillary lymph node side US feature axillary lymph node: size (mm of short-axis) US feature axillary lymph node: focal cortical thickening US feature axillary lymph node: visible hilar fat US BI-RADS Performed biopsy Histology after biopsy Vaccination date US date
1 29 No Left 18 No Yes E3 No No 02/2021 03/2021
2 66 Yes: in 2017 IDC in left breast with negative ipsilateral axillary lymph nodes Left 22 No Yes E4b Yes normal lymphocytes and histiocytes in hematoxylin-eosin staining 02/2021 03/2021
3 34 No Right 11 Yes Yes E3 No 02/2021 03/2021
4 54 Yes: in 2015 DCIS in left breast with negative ipsilateral axillary lymph nodes Left 23 No Yes E4b Yes normal lymphocytes and histiocytes in hematoxylin-eosin staining 03/2021 04/2021
5 74 No Left 15 Yes Yes E3 No 03/2021 04/2021
6 46 Yes: in 2018 IDC in left breast with negative ipsilateral axillary lymph nodes Left 13 Yes Yes E4b Yes normal lymphocytes and histiocytes in hematoxylin-eosin staining 03/2021 05/2021
7 76 Yes: in 2018 IDC in right breast with negative ipsilateral axillary lymph nodes Right 20 No Yes E4b Yes normal lymphocytes and histiocytes in hematoxylin-eosin staining 04/2021 05/2021
8 59 Yes: in 2020 IDC in left breast with negative ipsilateral axillary lymph nodes Left 20 No Yes E4b Yes normal lymphocytes and histiocytes in hematoxylin-eosin staining 04/2021 05/2021
9 39 No Left 22 No Yes E3 No 05/2021 05/20121
10 28 No Right 20 Yes Yes E3 No 05/2021 05/2021
eISSN:
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Language:
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Journal Subjects:
Medicine, Basic Medical Science, other
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