<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_jou.2017.0036_s_001"><h3>Aim of the study</h3><p>High-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy.</p></sec><sec id="j_jou.2017.0036_s_002"><h3>Material and methods</h3><p>75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs.</p></sec><sec id="j_jou.2017.0036_s_003"><h3>Results</h3><p>The mean cross sectional area (22.63 +/− 2.66 mm<sup>2</sup>) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (<italic>p</italic> &lt; 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/− 1.72 mm<sup>2</sup>) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/− 1.01 mm<sup>2</sup> and 0.30 mm respectively).</p></sec><sec id="j_jou.2017.0036_s_004"><h3>Conclusion</h3><p>The cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients.</p></sec></abstract>

Aim of the studyHigh-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study was aimed at finding out the correlation of the cross sectional area and maximum thickness of nerve fascicles of the tibial nerve with the presence and severity of diabetic peripheral neuropathy.Material and methods75 patients with type 2 diabetes mellitus clinically diagnosed with diabetic peripheral neuropathy were analysed, and the severity of neuropathy was determined using the Toronto Clinical Neuropathy Score. 58 diabetic patients with no clinical suspicion of diabetic peripheral neuropathy and 75 healthy non-diabetic subjects were taken as controls. The cross sectional area and maximum thickness of nerve fascicles of the tibial nerves were calculated 3 cm cranial to the medial malleolus in both lower limbs.ResultsThe mean cross sectional area (22.63 +/− 2.66 mm2) and maximum thickness of nerve fascicles (0.70 mm) of the tibial nerves in patients with diabetic peripheral neuropathy compared with both control groups was significantly larger, and statistically significant correlation was found with the Toronto Clinical Neuropathy Score (p < 0.001). The diabetic patients with no signs of peripheral neuropathy had a larger mean cross sectional area (14.40 +/− 1.72 mm2) and maximum thickness of nerve fascicles of the tibial nerve (0.40 mm) than healthy non-diabetic subjects (12.42 +/− 1.01 mm2 and 0.30 mm respectively).ConclusionThe cross sectional area and maximum thickness of nerve fascicles of the tibial nerve is larger in diabetic patients with or without peripheral neuropathy than in healthy control subjects, and ultrasonography can be used as a good screening tool in these patients.

High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy

Journal of Ultrasonography

This work is licensed under the Creative Commons Attribution-NonCommercial 3.0 Public License.

Aim of the studyHigh-resolution ultrasonography of the tibial nerve is a fast and non invasive tool for diagnosis of diabetic peripheral neuropathy. Our study...

High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy

Article Category: research-article

Published Online: Dec 29, 2017

Page range: 246 - 252

Received: Sep 05, 2017

Accepted: Oct 18, 2017

DOI: https://doi.org/10.15557/jou.2017.0036

Keywords
diabetes mellitus, tibial nerve, ultrasonography

© 2017 Kunwarpal Singh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial 3.0 Public License.

High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy

Article Category: research-article

Published Online: Dec 29, 2017

Page range: 246 - 252

Received: Sep 05, 2017

Accepted: Oct 18, 2017

DOI: https://doi.org/10.15557/jou.2017.0036

Keywordsdiabetes mellitus, tibial nerve, ultrasonography

© 2017 Kunwarpal Singh et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial 3.0 Public License.

Keywords
diabetes mellitus, tibial nerve, ultrasonography