<abstract xmlns="http://www.w3.org/1999/xhtml"><p>This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.</p></abstract>

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Slovak University of Technology in Bratislava, Faculty of Mechanical Engineering, Institute of Process Engineering, Nám. Slobody 17, 812 31 Bratislava, Slovakia

Slovak University of Technology in Bratislava, Faculty of Mechanical Engineering, Institute of Technologies and Materials, Pionierska 15,831 02 Bratislava, Slovakia

Strojnícky časopis - Journal of Mechanical Engineering

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations"}

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel,...

Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Published Online: Aug 19, 2016

Page range: 65 - 82

DOI: https://doi.org/10.1515/scjme-2016-0012

Keywords
Compaction equation, tabletting, angle of internal friction, angle of wall friction

© 2016 Peciar Peter et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Published Online: Aug 19, 2016

Page range: 65 - 82

DOI: https://doi.org/10.1515/scjme-2016-0012

KeywordsCompaction equation, tabletting, angle of internal friction, angle of wall friction

© 2016 Peciar Peter et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Compaction equation, tabletting, angle of internal friction, angle of wall friction