<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Objective</bold>. Histiocytic sarcoma (HS) is an extraordinary rare tumor and it has an offensive clinical course. HS of the uterine cervix is a far uncommon tumor with just a few cases described so far. Here we presented a case of primary HS of the uterine cervix in a 62-year-old female initially misdiagnosed as large cell non-keratinizing squamous cell carcinoma. To the best of our knowledge, this is the first reported case of HS of the uterine cervix from Iran.<bold>Case report</bold>. The patient presented with post-menopausal vaginal bleeding. Further evaluations revealed the presence of a relatively large cervical mass that was sampled. Under the preliminary diagnosis of large cell non-keratinizing squamous cell carcinoma, the patient underwent radical surgery. Postoperative pathological examination confirmed the diagnosis of HS of the uterine cervix. The patient received chemotherapy.<bold>Conclusion</bold>. Clinical presentations of HS of the uterine cervix are very similar to more common cervical tumors; as a result its diagnosis relies on immunohistochemical methods. A correct diagnose could lead to the proper and timely treatment.</abstract>

Objective. Histiocytic sarcoma (HS) is an extraordinary rare tumor and it has an offensive clinical course. HS of the uterine cervix is a far uncommon tumor with just a few cases described so far. Here we presented a case of primary HS of the uterine cervix in a 62-year-old female initially misdiagnosed as large cell non-keratinizing squamous cell carcinoma. To the best of our knowledge, this is the first reported case of HS of the uterine cervix from Iran.Case report. The patient presented with post-menopausal vaginal bleeding. Further evaluations revealed the presence of a relatively large cervical mass that was sampled. Under the preliminary diagnosis of large cell non-keratinizing squamous cell carcinoma, the patient underwent radical surgery. Postoperative pathological examination confirmed the diagnosis of HS of the uterine cervix. The patient received chemotherapy.Conclusion. Clinical presentations of HS of the uterine cervix are very similar to more common cervical tumors; as a result its diagnosis relies on immunohistochemical methods. A correct diagnose could lead to the proper and timely treatment.

Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity

Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd,

Department of Obstetrics and Gynaecology, Shahid Sadoughi University of Medical Sciences, Yazd,

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity"}

Objective. Histiocytic sarcoma (HS) is an extraordinary rare tumor and it has an offensive clinical course. HS of the uterine cervix is a far uncommon tumor...

Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity

Published Online: Mar 04, 2017

Page range: 53 - 56

Received: Jul 21, 2016

DOI: https://doi.org/10.1515/rjim-2016-0051

Keywords
Histiocytic sarcoma, Uterine cervix

© 2017 Fariba Binesh et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity

Published Online: Mar 04, 2017

Page range: 53 - 56

Received: Jul 21, 2016

DOI: https://doi.org/10.1515/rjim-2016-0051

KeywordsHistiocytic sarcoma, Uterine cervix

© 2017 Fariba Binesh et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Histiocytic sarcoma, Uterine cervix