<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Hepatorenal syndrome (HRS) is defined as renal failure that occurs in the presence of severe acute or chronic liver disease in the absence of underlying renal pathology. Due to the functional nature of the disease and the absence of specific diagnostic markers, HRS diagnosis is determined based on positive criteria associated with excluding other causes of renal failure in patients with liver cirrhosis and ascites. Differentiation from other types of acute or chronic renal disease is extremely difficult and therapeutic options are limited, prophylactic behavior is most appropriate in patients with severe hepatic disease and risk factors for the installation of hepatorenal syndrome.</p><p>Highlighting all precipitating factors of acute renal insufficiency and therapeutic modalities in order to minimize adverse events is an important step in improving the follow-up of the patients with liver cirrhosis. The prognosis is reserved especially for type 1 HRS. Liver transplantation is the best option for patients without contraindications. The therapies introduced in recent years, such as vasoconstrictor drugs or transjugular intrahepatic portosystemic shunt are effective methods in the renal function improvement.</p></abstract>

Hepatorenal syndrome (HRS) is defined as renal failure that occurs in the presence of severe acute or chronic liver disease in the absence of underlying renal pathology. Due to the functional nature of the disease and the absence of specific diagnostic markers, HRS diagnosis is determined based on positive criteria associated with excluding other causes of renal failure in patients with liver cirrhosis and ascites. Differentiation from other types of acute or chronic renal disease is extremely difficult and therapeutic options are limited, prophylactic behavior is most appropriate in patients with severe hepatic disease and risk factors for the installation of hepatorenal syndrome.Highlighting all precipitating factors of acute renal insufficiency and therapeutic modalities in order to minimize adverse events is an important step in improving the follow-up of the patients with liver cirrhosis. The prognosis is reserved especially for type 1 HRS. Liver transplantation is the best option for patients without contraindications. The therapies introduced in recent years, such as vasoconstrictor drugs or transjugular intrahepatic portosystemic shunt are effective methods in the renal function improvement.

Hepatorenal Syndrome: Diagnosis and Treatment – newsreel –

University of Medicine and Pharmacy, Craiova,

University of Medicine and Pharmacy, Craiova, Romania

Romanian Journal of Internal Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Hepatorenal Syndrome: Diagnosis and Treatment \u2013 newsreel \u2013"}

Hepatorenal syndrome (HRS) is defined as renal failure that occurs in the presence of severe acute or chronic liver disease in the absence of underlying renal...

Hepatorenal Syndrome: Diagnosis and Treatment – newsreel –

Published Online: Sep 22, 2016

Page range: 143 - 150

Received: Feb 03, 2016

DOI: https://doi.org/10.1515/rjim-2016-0024

Keywords
hepatorenal syndrome, liver cirrhosis, renal failure, serum creatinine, vasoconstrictors

© 2016

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Hepatorenal Syndrome: Diagnosis and Treatment – newsreel –

Published Online: Sep 22, 2016

Page range: 143 - 150

Received: Feb 03, 2016

DOI: https://doi.org/10.1515/rjim-2016-0024

Keywordshepatorenal syndrome, liver cirrhosis, renal failure, serum creatinine, vasoconstrictors

© 2016

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
hepatorenal syndrome, liver cirrhosis, renal failure, serum creatinine, vasoconstrictors