<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Background</bold>. Diabetes mellitus is a massive, growing, silent epidemic that has the potential to cripple health services in all parts of the world. Currently, a diagnosis of diabetes is achieved by evaluating plasma glucose levels. Saliva offers some distinctive advantages. Whole saliva can be collected non-invasively and by individuals with limited training. The present study was aimed to estimate and correlate the plasma and salivary glucose levels in diabetic and non diabetic subjects, with special reference to age.<bold>Method</bold>. The study population consisted of three groups: Group 1 consisted of diabetics with BGL>200mg/dl and Group 2 consisted of diabetics with BGL 130-200mg/dl based on their random plasma glucose levels. Group 3 consisted of healthy population as controls with BGL &lt;130 mg/dl. 2 ml of peripheral blood was collected for the estimation of random plasma glucose levels and unstimulated saliva was collected for the estimation of salivary glucose<bold>Results</bold>. The salivary glucose levels were significantly higher in group 1 and group 2 diabetics when compared with controls. The salivary glucose levels show a significant correlation with plasma glucose levels between study populations, suggesting that salivary glucose levels can be used as a monitoring tool for predicting glucose level in diabetic patients.<bold>Conclusion</bold>. The present study found that estimation of salivary glucose levels can be used as a noninvasive, painless technique for the measurement of diabetic status of a patient in a dental set up.</abstract>

Background. Diabetes mellitus is a massive, growing, silent epidemic that has the potential to cripple health services in all parts of the world. Currently, a diagnosis of diabetes is achieved by evaluating plasma glucose levels. Saliva offers some distinctive advantages. Whole saliva can be collected non-invasively and by individuals with limited training. The present study was aimed to estimate and correlate the plasma and salivary glucose levels in diabetic and non diabetic subjects, with special reference to age.Method. The study population consisted of three groups: Group 1 consisted of diabetics with BGL>200mg/dl and Group 2 consisted of diabetics with BGL 130-200mg/dl based on their random plasma glucose levels. Group 3 consisted of healthy population as controls with BGL <130 mg/dl. 2 ml of peripheral blood was collected for the estimation of random plasma glucose levels and unstimulated saliva was collected for the estimation of salivary glucoseResults. The salivary glucose levels were significantly higher in group 1 and group 2 diabetics when compared with controls. The salivary glucose levels show a significant correlation with plasma glucose levels between study populations, suggesting that salivary glucose levels can be used as a monitoring tool for predicting glucose level in diabetic patients.Conclusion. The present study found that estimation of salivary glucose levels can be used as a noninvasive, painless technique for the measurement of diabetic status of a patient in a dental set up.

Glucose Level Estimation in Diabetes Mellitus By Saliva: A Bloodless Revolution

Oral Pathology & Microbiology, Forensic Odontology School of Dental Sciences, Krishna Institute of Medical Sciences University, Malkapur, Karad-415539, Satara (Dist.), Maharashtra, India

Public Health Dentistry School of Dental Sciences, Krishna Institute of Medical Sciences University, Malkapur, Karad-415539, Satara (Dist.), Maharashtra, India

Romanian Journal of Internal Medicine

This chapter is distributed under the terms of the Creative Commons Attribution 4.0 Public License.

{"article-title":"Glucose Level Estimation in Diabetes Mellitus By Saliva: A Bloodless Revolution"}

Background. Diabetes mellitus is a massive, growing, silent epidemic that has the potential to cripple health services in all parts of the world. Currently, a...

Glucose Level Estimation in Diabetes Mellitus By Saliva: A Bloodless Revolution

Published Online: Oct 14, 2015

Page range: 248 - 252

Received: Mar 23, 2015

DOI: https://doi.org/10.1515/rjim-2015-0032

Keywords
glucose, diabetes mellitus, saliva, noninvasive

© 2015 Vidya Kadashetti et al., published by De Gruyter Open

This chapter is distributed under the terms of the Creative Commons Attribution 4.0 Public License.

Glucose Level Estimation in Diabetes Mellitus By Saliva: A Bloodless Revolution

Published Online: Oct 14, 2015

Page range: 248 - 252

Received: Mar 23, 2015

DOI: https://doi.org/10.1515/rjim-2015-0032

Keywordsglucose, diabetes mellitus, saliva, noninvasive

© 2015 Vidya Kadashetti et al., published by De Gruyter Open

This chapter is distributed under the terms of the Creative Commons Attribution 4.0 Public License.

Keywords
glucose, diabetes mellitus, saliva, noninvasive