<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction</bold>Muscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values of perfusion indexes and perfusion reserve. The investigation of the microcirculation has a crucial role in determining the muscle perfusion.<bold>Materials and method</bold>The study included 30 examinees, 24–74 years of age, without a history of confirmed peripheral artery disease and all had normal findings on Doppler ultrasonography and pedo-brachial index of lower extremity (PBI).99mTc-MIBI tissue muscle perfusion scintigraphy of lower limbs evaluates tissue perfusion in resting condition “rest study” and after workload “stress study”, through quantitative parameters: Inter-extremity index (for both studies), left thigh/right thigh (LT/RT) left calf/right calf (LC/RC) and perfusion reserve (PR) for both thighs and calves.<bold>Results</bold>In our investigated group we assessed the normal values of quantitative parameters of perfusion indexes. Indexes ranged for LT/RT in rest study 0.91-1.05, in stress study 0.92-1.04. LC/RC in rest 0.93-1.07 and in stress study 0.93-1.09. The examinees older than 50 years had insignificantly lower perfusion reserve of these parameters compared with those younger than 50, LC (p=0.98), and RC (p=0.6).<bold>Conclusion</bold>This non-invasive scintigraphic method allows in individuals without peripheral artery disease to determine the range of normal values of muscle perfusion at rest and stress condition and to clinically implement them in evaluation of patients with peripheral artery disease for differentiating patients with normal from those with impaired lower limbs circulation.</abstract>

IntroductionMuscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values of perfusion indexes and perfusion reserve. The investigation of the microcirculation has a crucial role in determining the muscle perfusion.Materials and methodThe study included 30 examinees, 24–74 years of age, without a history of confirmed peripheral artery disease and all had normal findings on Doppler ultrasonography and pedo-brachial index of lower extremity (PBI).99mTc-MIBI tissue muscle perfusion scintigraphy of lower limbs evaluates tissue perfusion in resting condition “rest study” and after workload “stress study”, through quantitative parameters: Inter-extremity index (for both studies), left thigh/right thigh (LT/RT) left calf/right calf (LC/RC) and perfusion reserve (PR) for both thighs and calves.ResultsIn our investigated group we assessed the normal values of quantitative parameters of perfusion indexes. Indexes ranged for LT/RT in rest study 0.91-1.05, in stress study 0.92-1.04. LC/RC in rest 0.93-1.07 and in stress study 0.93-1.09. The examinees older than 50 years had insignificantly lower perfusion reserve of these parameters compared with those younger than 50, LC (p=0.98), and RC (p=0.6).ConclusionThis non-invasive scintigraphic method allows in individuals without peripheral artery disease to determine the range of normal values of muscle perfusion at rest and stress condition and to clinically implement them in evaluation of patients with peripheral artery disease for differentiating patients with normal from those with impaired lower limbs circulation.

Normal Values of Tissue-Muscle Perfusion Indexes of Lower Limbs Obtained with a Scintigraphic Method

Macedonia (the former Yugoslav Republic of)

Institute of Pathophysiology and Nuclear Medicine, Acad “Isak S. Tadzer”, Medical Faculty, Skopje, R. MacedoniaUniversity Cardiology Clinic

University Stt Cyril and Methodius Skopje

Institute of Medical Physiology and Antropology, Medical Faculty

Institute of Epidemiology and Biostatistics with Medical Informatics, Medical Faculty

PRILOZI

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

IntroductionMuscle perfusion is a physiologic process that can undergo quantitative assessment and thus define the range of normal values of perfusion indexes...

Normal Values of Tissue-Muscle Perfusion Indexes of Lower Limbs Obtained with a Scintigraphic Method

Published Online: Oct 07, 2017

Page range: 55 - 61

DOI: https://doi.org/10.1515/prilozi-2017-0022

Keywords
muscle perfusion, 99mTc-MIBI scintigraphy, lower limbs, perfusion reserve

© 2017 Nevena Manevska et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Normal Values of Tissue-Muscle Perfusion Indexes of Lower Limbs Obtained with a Scintigraphic Method

Published Online: Oct 07, 2017

Page range: 55 - 61

DOI: https://doi.org/10.1515/prilozi-2017-0022

Keywordsmuscle perfusion, 99mTc-MIBI scintigraphy, lower limbs, perfusion reserve

© 2017 Nevena Manevska et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
muscle perfusion, 99mTc-MIBI scintigraphy, lower limbs, perfusion reserve