The paper presents an original method of calculation of the fatigue persistence based on the adoption of the load spectrum in the form of a correlation table, two-parameter fatigue characteristics and the linear hypothesis of fatigue damage summation. The calculation results by the proposed method were compared with the results of fatigue tests programmed for node-seal construction. On the basis of a comparative analysis of the test results and calculations conclusions regarding the usefulness of the proposed method to evaluate the fatigue persistence of components have been reached.