<abstract xmlns="http://www.w3.org/1999/xhtml">

Pharmaceuticals are commonly found in water collected from wastewater treatment plants, fresh water and saline water. Their presence in water may result in constant accumulation in living organisms, and consequently a negative impact on those organisms. Abiotic samples collected from the Gulf of Gdańsk were already proven to be polluted by several classes of pharmaceuticals, but the bioaccumulation was not investigated as far. This study presents the first results on the accumulation of pharmaceuticals in <italic>Mytilus edulis trossulus</italic> (Gould 1890) mussels collected from the Gulf of Gdańsk. The content of target 6 non-steroidal anti-inflammatory pharmaceuticals (ibuprofen, flurbiprofen, diclofenac, paracetamol, naproxen, ketoprofen) and 17α-ethynylestradiol in water and tissue samples was determined. The selected pharmaceuticals (paracetamol, flurbiprofen, 17α-ethynylestradiol) were found only in the largest individuals. The in situ BAFs calculated for paracetamol and flurbiprofen were 2850 and 16154 l kg-1 (dry weight), respectively, suggesting a high potential for the bioaccumulation of these compounds. The synthetic hormone 17α-ethynylestradiol was also found in the collected mussels at the concentration of 310 ng g-1 of dry weight. Generally, the examined mussels showed poor condition and it is highly likely that the accumulated pharmaceuticals are one of the important factors contributing to this.
</abstract>

Pharmaceuticals are commonly found in water collected from wastewater treatment plants, fresh water and saline water. Their presence in water may result in constant accumulation in living organisms, and consequently a negative impact on those organisms. Abiotic samples collected from the Gulf of Gdańsk were already proven to be polluted by several classes of pharmaceuticals, but the bioaccumulation was not investigated as far. This study presents the first results on the accumulation of pharmaceuticals in Mytilus edulis trossulus (Gould 1890) mussels collected from the Gulf of Gdańsk. The content of target 6 non-steroidal anti-inflammatory pharmaceuticals (ibuprofen, flurbiprofen, diclofenac, paracetamol, naproxen, ketoprofen) and 17α-ethynylestradiol in water and tissue samples was determined. The selected pharmaceuticals (paracetamol, flurbiprofen, 17α-ethynylestradiol) were found only in the largest individuals. The in situ BAFs calculated for paracetamol and flurbiprofen were 2850 and 16154 l kg-1 (dry weight), respectively, suggesting a high potential for the bioaccumulation of these compounds. The synthetic hormone 17α-ethynylestradiol was also found in the collected mussels at the concentration of 310 ng g-1 of dry weight. Generally, the examined mussels showed poor condition and it is highly likely that the accumulated pharmaceuticals are one of the important factors contributing to this.

Screening of 17α-ethynylestradiol and non-steroidal anti-inflammatory pharmaceuticals accumulation in <italic>Mytilus edulis trossulus</italic> (Gould, 1890) collected from the Gulf of Gdańsk

Department of Environmental Analysis, Institute of Environmental and Human Health Protection, Faculty of Chemistry

Department of Experimental Ecology of Marine Organisms, Institute of Oceanography, Faculty of Oceanography and Geography

Oceanological and Hydrobiological Studies

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Screening of 17α-ethynylestradiol and non-steroidal anti-inflammatory pharmaceuticals accumulation in  (Gould, 1890) collected from the Gulf of Gdańsk

Pharmaceuticals are commonly found in water collected from wastewater treatment plants, fresh water and saline water. Their presence in water may result in...

Screening of 17α-ethynylestradiol and non-steroidal anti-inflammatory pharmaceuticals accumulation in Mytilus edulis trossulus (Gould, 1890) collected from the Gulf of Gdańsk

Article Category: Short communication

Published Online: Dec 12, 2016

Page range: 605 - 614

Received: Apr 11, 2016

Accepted: Jun 09, 2016

DOI: https://doi.org/10.1515/ohs-2016-0050

Keywords
pharmaceutical residues, pharmaceutical bioaccumulation, sp., 17α-ethynylestradiol (EE2), non-steroidal anti-inflammatory drugs (NSAIDs)

© Faculty of Oceanography and Geography, University of Gdańsk, Poland. All rights reserved.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Screening of 17α-ethynylestradiol and non-steroidal anti-inflammatory pharmaceuticals accumulation in Mytilus edulis trossulus (Gould, 1890) collected from the Gulf of Gdańsk

Article Category: Short communication

Published Online: Dec 12, 2016

Page range: 605 - 614

Received: Apr 11, 2016

Accepted: Jun 09, 2016

DOI: https://doi.org/10.1515/ohs-2016-0050

Keywordspharmaceutical residues, pharmaceutical bioaccumulation, sp., 17α-ethynylestradiol (EE2), non-steroidal anti-inflammatory drugs (NSAIDs)

© Faculty of Oceanography and Geography, University of Gdańsk, Poland. All rights reserved.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
pharmaceutical residues, pharmaceutical bioaccumulation, sp., 17α-ethynylestradiol (EE2), non-steroidal anti-inflammatory drugs (NSAIDs)