Open Access

Myocardial Contrast Agents – Safety Considerations and Clinical Efficacy in Stress Echocardiography


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1. Olszewski, R., Timperley, J., Szmigielski, C., Monaghan, M., Nihoyannopoulos, P., Senior, R., & Becher, H. (2007). The clinical applications of contrast echocardiography. Eur J Echocardiogr, 8(3), S13-23. doi:10.1016/j.euje.2007.03.02110.1016/j.euje.2007.03.021Search in Google Scholar

2. Mulvagh, S. L., Rakowski, H., Vannan, M. A., Abdelmoneim, S. S., Becher, H., Bierig, S. M., Burns, P. N., Castello, R., Coon, P. D., Hagen, M. E., Jollis, J. G., Kimball, T. R., Kitzman, D. W., Kronzon, I., Labovitz, A. J., Lang, R. M., Mathew, J., Moir, W. S., Nagueh, S. F., Pearlman, A. S., Perez, J. E., Porter, T. R., Rosenbloom, J., Strachan, G. M., Thanigaraj, S., Wei, K., Woo, A., Yu, E. H., Zoghbi, W. A., & American Society of, E. (2008). American Society of Echocardiography Consensus Statement on the Clinical Applications of Ultrasonic Contrast Agents in Echocardiography. J Am Soc Echocardiogr, 21(11), 1179-1201; quiz 1281. doi:10.1016/j.echo.2008.09.00910.1016/j.echo.2008.09.009Search in Google Scholar

3. Weissman, N. J., Cohen, M. C., Hack, T. C., Gillam, L. D., Cohen, J. L., & Kitzman, D. W. (2000). Infusion versus bolus contrast echocardiography: a multicenter, open-label, crossover trial. Am Heart J, 139(3), 399-404.10.1016/S0002-8703(00)90082-6Search in Google Scholar

4. Thanigaraj, S., Nease, R. F., Jr., Schechtman, K. B., Wade, R. L., Loslo, S., & Perez, J. E. (2001). Use of contrast for image enhancement during stress echocardiography is cost-effective and reduces additional diagnostic testing. Am J Cardiol, 87(12), 1430-1432.10.1016/S0002-9149(01)01573-9Search in Google Scholar

5. Senior, R., Becher, H., Monaghan, M., Agati, L., Zamorano, J., Vanoverschelde, J. L., & Nihoyannopoulos, P. (2009). Contrast echocardiography: evidence-based recommendations by European Association of Echocardiography. Eur J Echocardiogr, 10(2), 194-212. doi:10.1093/ejechocard/jep00510.1093/ejechocard/jep005Search in Google Scholar

6. Mulvagh, S. L., DeMaria, A. N., Feinstein, S. B., Burns, P. N., Kaul, S., Miller, J. G., Monaghan, M., Porter, T. R., Shaw, L. J., & Villanueva, F. S. (2000). Contrast echocardiography: current and future applications. J Am Soc Echocardiogr, 13(4), 331-342.10.1067/mje.2000.105462Search in Google Scholar

7. Quaia, E. (2006). Contrast Media in Ultrasonography: Basic Principles and Clinical Applications: Springer Berlin Heidelberg.Search in Google Scholar

8. Gramiak, R., & Shah, P. M. (1968). Echocardiography of the aortic root. Invest Radiol, 3(5), 356-366.10.1097/00004424-196809000-00011Search in Google Scholar

9. Feinstein, S. B., Shah, P. M., Bing, R. J., Meerbaum, S., Corday, E., Chang, B. L., Santillan, G., & Fujibayashi, Y. (1984). Microbubble dynamics visualized in the intact capillary circulation. J Am Coll Cardiol, 4(3), 595-600..10.1016/S0735-1097(84)80107-2Search in Google Scholar

10. Shapiro, J. R., Reisner, S. A., Lichtenberg, G. S., & Meltzer, R. S. (1990). Intravenous contrast echocardiography with use of sonicated albumin in humans: systolic disappearance of left ventricular contrast after transpulmonary transmission. J Am Coll Cardiol, 16(7), 1603-1607..10.1016/0735-1097(90)90308-CSearch in Google Scholar

11. Feinstein, S. B., Cheirif, J., Ten Cate, F. J., Silverman, P. R., Heidenreich, P. A., Dick, C., Desir, R. M., Armstrong, W. F., Quinones, M. A., & Shah, P. M. (1990). Safety and efficacy of a new transpulmonary ultrasound contrast agent: initial multicenter clinical results. J Am Coll Cardiol, 16(2), 316-324.10.1016/0735-1097(90)90580-ISearch in Google Scholar

12. Schlief, R., Staks, T., Mahler, M., Rufer, M., Fritzsch, T., & Seifert, W. (1990). Successful opacification of the left heart chambers on echocardiographic examination after intravenous injection of a new saccharide based contrast agent. Echocardiography, 7(1), 61-64.10.1111/j.1540-8175.1990.tb00349.xSearch in Google Scholar

13. Beppu, S., Matsuda, H., Shishido, T., Matsumura, M., & Miyatake, K. (1997). Prolonged myocardial contrast echocardiography via peripheral venous administration of QW3600 injection (EchoGen): its efficacy and side effects. J Am Soc Echocardiogr, 10(1), 11-2410.1016/S0894-7317(97)80028-4Search in Google Scholar

14. GE Healthcare. (2008). OPTISON prescribing Information. Retrieved from http://www.amershamhealth-us.com/optison/Search in Google Scholar

15. Skyba, D. M., Camarano, G., Goodman, N. C., Price, R. J., Skalak, T. C., & Kaul, S. (1996). Hemodynamic characteristics, myocardial kinetics and microvascular rheology of FS-069, a second-generation echocardiographic contrast agent capable of producing myocardial opacification from a venous injection. J Am Coll Cardiol, 28(5), 1292-1300. doi:10.1016/S0735-1097(96)00328-210.1016/S0735-1097(96)00328-2Search in Google Scholar

16. Luminity Summary of Product Characteristics. (2008). Retrieved from http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000654/WC500045020.pdfSearch in Google Scholar

17. Definity-FDA prescribing information, side effects and uses (2001). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021064s011lbl.pdfSearch in Google Scholar

18. Sontum, P. C. (2008). Physicochemical characteristics of Sonazoid, a new contrast agent for ultrasound imaging. Ultrasound Med Biol, 34(5), 824-833. doi:10.1016/j.ultrasmedbio.2007.11.00610.1016/j.ultrasmedbio.2007.11.00618255220Search in Google Scholar

19. SonoVue INN-sulphur hexafluoride- European Medicines Agency (2014). Retrieved from www.ema.europa.euSearch in Google Scholar

20. Dolan, M. S., Gala, S. S., Dodla, S., Abdelmoneim, S. S., Xie, F., Cloutier, D., Bierig, M., Mulvagh, S. L., Porter, T. R., & Labovitz, A. J. (2009). Safety and efficacy of commercially available ultrasound contrast agents for rest and stress echocardiography a multicenter experience. J Am Coll Cardiol, 53(1), 32-38. doi:10.1016/j.jacc.2008.08.06610.1016/j.jacc.2008.08.06619118722Search in Google Scholar

21. Main, M. L., Goldman, J. H., & Grayburn, P. A. (2007). Thinking outside the “box”-the ultrasound contrast controversy. J Am Coll Cardiol, 50(25), 2434-2437. doi:10.1016/j.jacc.2007.11.00610.1016/j.jacc.2007.11.00618154971Search in Google Scholar

22. Main, M. L., Hibberd, M. G., Ryan, A., Lowe, T. J., Miller, P., & Bhat, G. (2014). Acute mortality in critically ill patients undergoing echocardiography with or without an ultrasound contrast agent. JACC Cardiovasc Imaging, 7(1), 40-48. doi:10.1016/j.jcmg.2013.08.012.10.1016/j.jcmg.2013.08.01224290568Search in Google Scholar

23. EMEA. Scientific Discussion. European Medicines Agency. (2004). Retrieved from CPMP/0053/01.http://www.emea.europa.eu/humandocs/human/epar/sonovue/sonovue.htmSearch in Google Scholar

24. Van Camp, G., Droogmans, S., & Cosyns, B. (2007). Bio-effects of ultrasound contrast agents in daily clinical practice: fact or fiction?†. European Heart Journal, 28(10), 1190-1192. doi:10.1093/eurheartj/ehm11010.1093/eurheartj/ehm11017470674Search in Google Scholar

25. EMEA. http://www.emea.europa.eu/, document reference: Emea/cpmp/212/04Search in Google Scholar

26. Porter, T. R., Abdelmoneim, S., Belcik, J. T., McCulloch, M. L., Mulvagh, S. L., Olson, J. J., Porcelli, C., Tsutsui, J. M., & Wei, K. (2014). Guidelines for the cardiac sonographer in the performance of contrast echocardiography: a focused update from the American Society of Echocardiography. J Am Soc Echocardiogr, 27(8), 797-810. doi:10.1016/j.echo.2014.05.01110.1016/j.echo.2014.05.01125085408Search in Google Scholar

27. Cosyns, B., Pasquet, A., Van Camp, G., Hernot, S., Droogmans, S., Unger, P., De Sutter, J., Lancellotti, P., & Belgian Working Group on Non-Invasive Cardiac, I. (2009). Safety of ultrasound contrast agents: “Primum non nocere”? Acta Cardiol, 64(4), 547-552. doi:10.2143/AC.64.4.204162210.2143/AC.64.4.204162219725450Search in Google Scholar

28. Schinkel, A. F., Kaspar, M., & Staub, D. (2015) Contrast-enhanced ultrasound: clinical applications in patients with atherosclerosis. Int J Cardiovasc Imaging. Advance online publication.10.1007/s10554-015-0713-z470684126206524Search in Google Scholar

29. Amyot, R., Morales, M. A., & Rovai, D. (2000). Contrast echocardiography for myocardial perfusion imaging using intravenous agents: progress and promises. Eur J Echocardiogr, 1(4), 233-243. doi:10.1053/euje.2000.003610.1053/euje.2000.003611916600Search in Google Scholar

30. Abdelmoneim, S. S., Bernier, M., Scott, C. G., Dhoble, A., Ness, S. A., Hagen, M. E., Moir, S., McCully, R. B., Pellikka, P. A., & Mulvagh, S. L. (2009). Safety of contrast agent use during stress echocardiography: a 4-year experience from a single-center cohort study of 26,774 patients. JACC Cardiovasc Imaging, 2(9), 1048-1056. doi:10.1016/j.jcmg.2009.03.02010.1016/j.jcmg.2009.03.02019761981Search in Google Scholar

31. Malhotra, V., Nwogu, J., Bondmass, M. D., Bean, M., Bieniarz, T., Tertell, M., Conliss, M., & Devries, S. (2000). Is the technically limited echocardiographic study an endangered species? endocardial border definition with native tissue harmonic imaging and Optison contrast: a review of 200 cases. J Am Soc Echocardiogr, 13(8), 771-773.10.1067/mje.2000.10607810936821Search in Google Scholar

32. Rainbird, A. J., Mulvagh, S. L., Oh, J. K., McCully, R. B., Klarich, K. W., Shub, C., Mahoney, D. W., & Pellikka, P. A. (2001). Contrast dobutamine stress echocardiography: clinical practice assessment in 300 consecutive patients. J Am Soc Echocardiogr, 14(5), 378-385.10.1067/mje.2001.11126411337683Search in Google Scholar

33. Shah, B. N., Chahal, N. S., Bhattacharyya, S., Li, W., Roussin, I., Khattar, R. S., & Senior, R. (2014). The feasibility and clinical utility of myocardial contrast echocardiography in clinical practice: results from the incorporation of myocardial perfusion assessment into clinical testing with stress echocardiography study. J Am Soc Echocardiogr, 27(5), 520-530. doi:10.1016/j.echo.2014.01.02810.1016/j.echo.2014.01.02824637056Search in Google Scholar

eISSN:
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Language:
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Journal Subjects:
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