<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Background</bold>: The main target of the structural damage in osteoarthritisis the hyaline cartilage. New options such as PRP (platelet rich plasma) may cause structural improvement of the cartilage.<bold>Objective</bold>: The aim of our study was to evaluate the evolution of the patients with knee osteoarthritis on PRP treatment.<bold>Material and method</bold>: The patients with osteoarthritis were evaluated at enrolment and every three months by ultrasound knee ecography. A semi-quantitative knee ultrasound score was applied to monitor changes before and after the treatment. The score was composed by the presence of the following: bursitis (1 point), hypoechogenic changes at the level of the hyaline cartilage in the anterior transversal window (1 point), asymmetrical narrowing of the cartilage (1 point), the involvement of the medial cartilage in the longitudinal approach (1 point), the involvement of lateral cartilage in the longitudinal approach (1 point) and the presence of step up lesions – osteophytes (1 point The evaluation was performed independently by two separate physicians. Another ultrasound - trained doctor was analysing all the images.<bold>Results</bold>: Twenty - nine patients were included in our study; with one patient excluded due to masive bursitis. No differences were found concerning the pathological findings between the first two evaluators (p: 0.1250). So far, only nine patients have been evaluated at three months, and we were unable to find any improvements or worsening concerning the ultrasound alterations (p: 0.0625). The ultrasound lack of modifications was not correlated with the functional status of the subjects.<bold>Conclusions</bold>: In the short term, the local treatment showed no improvement on structural damage, but it improved the overall status of the patients (less pain, improved mobility, a better quality of life).</abstract>

Background: The main target of the structural damage in osteoarthritisis the hyaline cartilage. New options such as PRP (platelet rich plasma) may cause structural improvement of the cartilage.Objective: The aim of our study was to evaluate the evolution of the patients with knee osteoarthritis on PRP treatment.Material and method: The patients with osteoarthritis were evaluated at enrolment and every three months by ultrasound knee ecography. A semi-quantitative knee ultrasound score was applied to monitor changes before and after the treatment. The score was composed by the presence of the following: bursitis (1 point), hypoechogenic changes at the level of the hyaline cartilage in the anterior transversal window (1 point), asymmetrical narrowing of the cartilage (1 point), the involvement of the medial cartilage in the longitudinal approach (1 point), the involvement of lateral cartilage in the longitudinal approach (1 point) and the presence of step up lesions – osteophytes (1 point The evaluation was performed independently by two separate physicians. Another ultrasound - trained doctor was analysing all the images.Results: Twenty - nine patients were included in our study; with one patient excluded due to masive bursitis. No differences were found concerning the pathological findings between the first two evaluators (p: 0.1250). So far, only nine patients have been evaluated at three months, and we were unable to find any improvements or worsening concerning the ultrasound alterations (p: 0.0625). The ultrasound lack of modifications was not correlated with the functional status of the subjects.Conclusions: In the short term, the local treatment showed no improvement on structural damage, but it improved the overall status of the patients (less pain, improved mobility, a better quality of life).

Minimally Invasive Treatment with Platelet Rich Plasma in Patients with Knee Osteoarthritis

Department of Orthopedic Surgery and Traumatology I, County Emergency Clinical Hospital, Târgu-Mureș,

Department of Rheumatology and Physiotherapy, County Emergency Clinical Hospital, Târgu-Mureș,

Department of ICU and Anesthesiology I, County Emergency Clinical Hospital, Târgu-Mureș,

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Background: The main target of the structural damage in osteoarthritisis the hyaline cartilage. New options such as PRP (platelet rich plasma) may cause...

Minimally Invasive Treatment with Platelet Rich Plasma in Patients with Knee Osteoarthritis

Published Online: Oct 21, 2016

Page range: 299 - 303

Received: Jul 21, 2015

Accepted: Sep 03, 2015

DOI: https://doi.org/10.1515/amma-2015-0094

Keywords
Osteoarthritis PRP ecography knee cartilage

© 2016 Albu Daniel–Emil et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Minimally Invasive Treatment with Platelet Rich Plasma in Patients with Knee Osteoarthritis

Published Online: Oct 21, 2016

Page range: 299 - 303

Received: Jul 21, 2015

Accepted: Sep 03, 2015

DOI: https://doi.org/10.1515/amma-2015-0094

KeywordsOsteoarthritis PRP ecography knee cartilage

© 2016 Albu Daniel–Emil et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Osteoarthritis PRP ecography knee cartilage