<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide variety of markers enzymes, proteins and cytokines are mainly used. While direct biomarkers reflect the stage of fibrosis and fibrinogenesis, indirect markers allow assessment of the general liver functions. The combination of direct and indirect markers increases the diagnostic reliability and therefore these panels and indices are investigated quite intensively in recent years in order to decrease the number of liver biopsies without completely replace it, which is still regarded as the reference method.</p></abstract>

Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide variety of markers enzymes, proteins and cytokines are mainly used. While direct biomarkers reflect the stage of fibrosis and fibrinogenesis, indirect markers allow assessment of the general liver functions. The combination of direct and indirect markers increases the diagnostic reliability and therefore these panels and indices are investigated quite intensively in recent years in order to decrease the number of liver biopsies without completely replace it, which is still regarded as the reference method.

Non-invasive Diagnostics of Liver Fibrosis

Acta Medica Bulgarica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Non-invasive Diagnostics of Liver Fibrosis"}

Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD),...

Non-invasive Diagnostics of Liver Fibrosis

Published Online: May 29, 2017

Page range: 50 - 56

DOI: https://doi.org/10.1515/amb-2017-0009

Keywords
liver fibrosis, liver biopsy, alcoholic liver disease, non-alcoholic fatty liver disease, chronic viral hepatitis B, chronic viral Hepatitis C

© 2017 R. Mihaylov et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Non-invasive Diagnostics of Liver Fibrosis

Published Online: May 29, 2017

Page range: 50 - 56

DOI: https://doi.org/10.1515/amb-2017-0009

Keywordsliver fibrosis, liver biopsy, alcoholic liver disease, non-alcoholic fatty liver disease, chronic viral hepatitis B, chronic viral Hepatitis C

© 2017 R. Mihaylov et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
liver fibrosis, liver biopsy, alcoholic liver disease, non-alcoholic fatty liver disease, chronic viral hepatitis B, chronic viral Hepatitis C