<abstract xmlns="http://www.w3.org/1999/xhtml"><p> A new optical method for reduction of local tissue hypoxia is proposed. It is shown that this method of phototherapy allows the control of a local oxygen concentration in tissue. Different aspects of biomedical application of this phenomenon are discussed. The results of in vivo experimental investigation of the laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels and its role in tissue oxygenation are presented. The rates of oxygen saturation SpO<sub>2</sub> in blood and their dependence on the wavelength of the transcutaneous laser irradiation have been experimentally measured.</p></abstract>

A new optical method for reduction of local tissue hypoxia is proposed. It is shown that this method of phototherapy allows the control of a local oxygen concentration in tissue. Different aspects of biomedical application of this phenomenon are discussed. The results of in vivo experimental investigation of the laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels and its role in tissue oxygenation are presented. The rates of oxygen saturation SpO2 in blood and their dependence on the wavelength of the transcutaneous laser irradiation have been experimentally measured.

Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels

Institute of Electronics, Bulgarian Academy of Sciences 72 Tzarigradsko Shausse Blvd.1784 Sofia, Bulgaria

Institute of Applied Problems of Physics and Biophysics, Academy of Sciences of Ukraine

Acta Medica Bulgarica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

A new optical method for reduction of local tissue hypoxia is proposed. It is shown that this method of phototherapy allows the control of a local oxygen...

Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels

Published Online: Nov 26, 2015

Page range: 42 - 48

DOI: https://doi.org/10.1515/amb-2015-0017

Keywords
oxyhemoglobin, tissue oxygenation, hypoxia, phototherapy, photodissociation

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels

Published Online: Nov 26, 2015

Page range: 42 - 48

DOI: https://doi.org/10.1515/amb-2015-0017

Keywordsoxyhemoglobin, tissue oxygenation, hypoxia, phototherapy, photodissociation

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
oxyhemoglobin, tissue oxygenation, hypoxia, phototherapy, photodissociation