<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Rhabdomyosarcoma is a malignant tumor of the skeletal muscles that is occasionally observed in free-living and pet birds. A case of malignant rhabdomyosarcoma in the musculature of the right wing of a captive female cockatiel <italic>(Nymphicus hollandicus)</italic> was investigated. The clinical aspect and radiographic images suggested an invasive neoplasm. Histologically, the tumor was composed of a patternless array of large primitive polygonal cells or sheets of bizarre cells with giant nuclei and atypical mitoses set in a collagenous stroma. Anaplastic cells were poorly differentiated and exhibited notable cellular and nuclear pleomorphism. Nuclei showed extreme variability in number, size, shape, chromatin distribution and nucleolar size and number. The cross striations were encountered in elongated multinucleated cells known as “strap cells” and in ovoid cells known as “racquet cells” and numerous mitotic figures were also observed. Neoplastic cells were positive for muscle actin and negative for desmin, suggesting the diagnosis of anaplastic rhabdomyosarcoma. It is the first reliable record of a rhabdomyosarcoma in a cockatiel <italic>(Nymphicus hollandicus)</italic> in Romania.</p></abstract>

Rhabdomyosarcoma is a malignant tumor of the skeletal muscles that is occasionally observed in free-living and pet birds. A case of malignant rhabdomyosarcoma in the musculature of the right wing of a captive female cockatiel (Nymphicus hollandicus) was investigated. The clinical aspect and radiographic images suggested an invasive neoplasm. Histologically, the tumor was composed of a patternless array of large primitive polygonal cells or sheets of bizarre cells with giant nuclei and atypical mitoses set in a collagenous stroma. Anaplastic cells were poorly differentiated and exhibited notable cellular and nuclear pleomorphism. Nuclei showed extreme variability in number, size, shape, chromatin distribution and nucleolar size and number. The cross striations were encountered in elongated multinucleated cells known as “strap cells” and in ovoid cells known as “racquet cells” and numerous mitotic figures were also observed. Neoplastic cells were positive for muscle actin and negative for desmin, suggesting the diagnosis of anaplastic rhabdomyosarcoma. It is the first reliable record of a rhabdomyosarcoma in a cockatiel (Nymphicus hollandicus) in Romania.

Description Of An Anaplastic Rhabdomyosarcoma In A Cockatiel (<italic>Nymphicus Hollandicus</italic>)

Department of Propedeutics and Surgical Techniques, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea Mănăştur 3-5, Cluj-Napoca, 400372, Romania

Department of Pathologic Anatomy, Necropsy and Veterinary Forensic Medicine, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea Mănăştur 3-5, Cluj-Napoca, 400372, Romania

Department of Histology, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea Mănăştur 3-5, Cluj-Napoca, 400372, Romania

Acta Veterinaria

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Description Of An Anaplastic Rhabdomyosarcoma In A Cockatiel ()

Rhabdomyosarcoma is a malignant tumor of the skeletal muscles that is occasionally observed in free-living and pet birds. A case of malignant rhabdomyosarcoma...

Description Of An Anaplastic Rhabdomyosarcoma In A Cockatiel (Nymphicus Hollandicus)

Published Online: Sep 30, 2015

Page range: 436 - 442

Received: Feb 18, 2015

Accepted: May 20, 2015

DOI: https://doi.org/10.1515/acve-2015-0036

Keywords
anaplastic rhabdomyosarcoma, cockatiel, immunohistochemistry, neoplasm, wing

© Ober Ciprian et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Description Of An Anaplastic Rhabdomyosarcoma In A Cockatiel (Nymphicus Hollandicus)

Published Online: Sep 30, 2015

Page range: 436 - 442

Received: Feb 18, 2015

Accepted: May 20, 2015

DOI: https://doi.org/10.1515/acve-2015-0036

Keywordsanaplastic rhabdomyosarcoma, cockatiel, immunohistochemistry, neoplasm, wing

© Ober Ciprian et al.

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
anaplastic rhabdomyosarcoma, cockatiel, immunohistochemistry, neoplasm, wing