Epidemiological study of congenital and hereditary anomalies in Sialkot District of Pakistan revealed a high incidence of limb and neurological disorders

[1]Center for Disease Control and Prevention [online]. 2016 [cited 2017 Jan 27]. Available from: https://www.cdc.gov/Center for Disease Control and Prevention [online]2016[cited 2017 Jan 27]. Available fromhttps://www.cdc.gov/Search in Google Scholar

[2]World Health Organization. Congenital anomalies, Factsheet [online]. 2016. [cited 2017 Jan 27]. Available from: http://www.who.int/mediacentre/factsheets/fs370/en/World Health Organization. Congenital anomalies, Factsheet [online]2016[cited 2017 Jan 27]. Available fromhttp://www.who.int/mediacentre/factsheets/fs370/en/Search in Google Scholar

[3]World Health Organization. Neonatal-perinatal database and birth defects surveillance. Report of the regional review meeting, New Delhi, India, 19–21 August 2014.World Health Organization. Neonatal-perinatal database and birth defects surveillanceReport of the regional review meetingNew Delhi, India19–21 August2014Search in Google Scholar

[4]EUROCAT. European Surveillance of Congenital Anomalies [online]. 2015. [cited 2017 Jan 17]. Available from: http://www.eurocat-network.eu/EUROCAT. European Surveillance of Congenital Anomalies [online]2015[cited 2017 Jan 17]. Available fromhttp://www.eurocat-network.eu/Search in Google Scholar

[5]Abdolahi HM, Maher MHK, Afsharnia F, Dastgiri S. Prevalence of congenital anomalies: a community-based study in the northwest of Iran. ISRN Pediatr. 2014; 920–40.AbdolahiHMMaherMHKAfsharniaFDastgiriSPrevalence of congenital anomalies: a community-based study in the northwest of IranISRN Pediatr20149204010.1155/2014/920940400502024995131Search in Google Scholar

[6]Ndibazza J, Lule S, Nampijja M, Mpairwe H, Oduru G, Kiggundu M, et al. A description of congenital anomalies among infants in Entebbe, Uganda. Birth Defects Res A Clin Mol Teratol. 2011; 91:857–61.NdibazzaJLuleSNampijjaMMpairweHOduruGKiggunduMet alA description of congenital anomalies among infants in Entebbe, UgandaBirth Defects Res A Clin Mol Teratol2011918576110.1002/bdra.20838327234421770020Search in Google Scholar

[7]Kumar S, Bano S. Comparison and analysis of health care delivery systems: Pakistan versus Bangladesh. J Hosp Med Manage. 2017; 3:1.KumarSBanoSComparison and analysis of health care delivery systems: Pakistan versus BangladeshJ Hosp Med Manage20173110.4172/2471-9781.100020Search in Google Scholar

[8]Hall JJ, Taylor R. Health for all beyond 2000: the demise of the Alma-Ata Declaration and primary health care in developing countries. Med J Aust. 2003; 178:17–20.HallJJTaylorRHealth for all beyond 2000: the demise of the Alma-Ata Declaration and primary health care in developing countriesMed J Aust2003178172010.5694/j.1326-5377.2003.tb05033.x12492384Search in Google Scholar

[9]United Nations, Department of Economic and Social Affairs, Population Division. 2015; World Population Prospects: The 2015 Revision.United Nations, Department of Economic and Social Affairs, Population Division2015World Population Prospects: The 2015 RevisionSearch in Google Scholar

[10]Arfaksad A, Wajahat Y. 2015. Frequency of fetal congenital anomalies and associated risk factors observed in pregnant women in a public sector hospital of Karachi. Ann Abbasi Shaheed Hosp Karachi Med Dent Coll. 2016; 21:139–46.ArfaksadAWajahatY.2015Frequency of fetal congenital anomalies and associated risk factors observed in pregnant women in a public sector hospital of KarachiAnn Abbasi Shaheed Hosp Karachi Med Dent Coll20162113946Search in Google Scholar

[11]Masood SN, Jamil N, Mumtaz SN, Masood MF, Muneer S. Congenital malformations in newborns of consanguineous and non-consanguineous parents. Pak J Med Sci. 2011; 27:1–5.MasoodSNJamilNMumtazSNMasoodMFMuneerSCongenital malformations in newborns of consanguineous and non-consanguineous parentsPak J Med Sci20112715Search in Google Scholar

[12]Gillani S, Kazmi NHS, Najeeb S, Hussain S, Raza A. Frequencies of congenital anomalies among newborns admitted in nursery of Ayub Teaching Hospital Abbottabad, Pakistan. J Ayub Med Coll Abbottabad. 2011; 23:117–21.GillaniSKazmiNHSNajeebSHussainSRazaAFrequencies of congenital anomalies among newborns admitted in nursery of Ayub Teaching Hospital Abbottabad, PakistanJ Ayub Med Coll Abbottabad20112311721Search in Google Scholar

[13]Hussain S, Sabir MU, Tarar SH, Mushtaq R. Prevalence and pattern of congenital malformations among neonates in the neonatal unit of a teaching hospital. J Pak Med Assoc. 2014; 64:629–34.HussainSSabirMUTararSHMushtaqRPrevalence and pattern of congenital malformations among neonates in the neonatal unit of a teaching hospitalJ Pak Med Assoc20146462934Search in Google Scholar

[14]Perveen F, Tyyab S. Frequency and pattern of distribution of congenital anomalies in the newborn and associated maternal risk factors. J Coll Physicians Surg Pak. 2007; 17:340–3.PerveenFTyyabSFrequency and pattern of distribution of congenital anomalies in the newborn and associated maternal risk factorsJ Coll Physicians Surg Pak2007173403Search in Google Scholar

[15]Shah N, Rohra DK, Shams H, Khan NH. Home deliveries: reasons and adverse outcomes in women presenting to a tertiary care hospital. J Pak Med Assoc. 2010; 60:555–8.ShahNRohraDKShamsHKhanNHHome deliveries: reasons and adverse outcomes in women presenting to a tertiary care hospitalJ Pak Med Assoc2010605558Search in Google Scholar

[16]National Institute of Population Studies (NIPS) [Pakistan] and ICF International. 2013. Pakistan Demographic and Health Survey 2012–13. Islamabad, Pakistan, and Calverton, Maryland, USA: NIPS and ICF International. [online] 2014. [cited 2017 Feb 05]. Available from:https://www.nips.org.pk/abstract_files/PDHS%20Final%20Report%20as%20of%20Jan%2022-2014.pdf.National Institute of Population Studies (NIPS) [Pakistan] and ICF International. 2013. Pakistan Demographic and Health Survey 2012–13Islamabad, Pakistan, and Calverton, Maryland, USANIPS and ICF International[online] 2014. [cited 2017 Feb 05]. Available fromhttps://www.nips.org.pk/abstract_files/PDHS%20Final%20Report%20as%20of%20Jan%2022-2014.pdfSearch in Google Scholar

[17]District Disaster Management Authority. Disaster Risk Management Plan. District Sialkot, Government of Punjab. DCO Office Sialkot [online]. 2008. [cited 2017 Jan 27]. Available from: http//www.ndma.gov.pkDistrict Disaster Management Authority. Disaster Risk Management Plan. District Sialkot, Government of Punjab. DCO Office Sialkot [online]2008[cited 2017 Jan 27]. Available fromhttp//www.ndma.gov.pkSearch in Google Scholar

[18]International Classification of Disease. [online] 2016. [cited 2017 Jan 15]. Available from: http://apps.who.int/classifications/icd10/browse/2016/enInternational Classification of Disease2016[cited 2017 Jan 15]. Available fromhttp://apps.who.int/classifications/icd10/browse/2016/enSearch in Google Scholar

[19]Online Mendelian Inheritance in Man. [online] 2016. [cited 2017 Feb 05]. Available fromhttp://www.ncbi.nlm.nih.gov/pubmedOnline Mendelian Inheritance in Man2016[cited 2017 Feb 05]. Available fromhttp://www.ncbi.nlm.nih.gov/pubmedSearch in Google Scholar

[20]ORPHANET. The portal for rare diseases and orphan drugs. [online] 2017. [cited 2017 Feb 13]. Available from: http://www.orpha.net/ORPHANET. The portal for rare diseases and orphan drugs[online]2017[cited 2017 Feb 13]. Available fromhttp://www.orpha.net/Search in Google Scholar

[21]Temtamy SA, McKusick VA. The genetics of hand malformations. New York: Alan R. Liss; 1978.TemtamySAMcKusickVAThe genetics of hand malformationsNew YorkAlan R. Liss1978Search in Google Scholar

[22]Malik S. Syndactyly: phenotypes, genetics and current classification. Eur J Hum Genet. 2012; 20:817–24.MalikSSyndactyly: phenotypes, genetics and current classificationEur J Hum Genet2012208172410.1038/ejhg.2012.14340072822333904Search in Google Scholar

[23]Malik S. Polydactyly: phenotypes, genetics and classification. Clin Genet. 2014; 85:203–12.MalikSPolydactyly: phenotypes, genetics and classificationClin Genet2014852031210.1111/cge.1227624020795Search in Google Scholar

[24]Korejo R, Bhutta S, Noorani KH, Bhutta ZA. An audit and trends of perinatal mortality at the Jinnah Postgraduate Medical Centre Karachi. J Pak Med Assoc. 2007; 57:168–71.KorejoRBhuttaSNooraniKHBhuttaZAAn audit and trends of perinatal mortality at the Jinnah Postgraduate Medical Centre KarachiJ Pak Med Assoc20075716871Search in Google Scholar

[25]Lal K, Malik S. Epidemiological study of congenital limb defects in individuals or families from the interior Sindh region of Pakistan. Asian Biomed (Res Rev News). 2015; 9:325–34.LalKMalikSEpidemiological study of congenital limb defects in individuals or families from the interior Sindh region of PakistanAsian Biomed (Res Rev News)2015932534Search in Google Scholar

[26]Khan A, Zuhaid M, Fayaz M, Ali F, Khan A, Ullah R, et al. Frequency of congenital anomalies in newborns and its relation to maternal health in a tertiary care hospital in Peshawar. Pakistan. Int J Med Students. 2015; 3:19–23.KhanAZuhaidMFayazMAliFKhanAUllahRet alFrequency of congenital anomalies in newborns and its relation to maternal health in a tertiary care hospital in PeshawarPakistan. Int J Med Students20153192310.5195/ijms.2015.108Search in Google Scholar

[27]Zahra Q, Shuaib M, Malik S. Epidemiology of congenital anomalies in the Kurram Tribal Agency, northwest Pakistan. Asian Biomed (Res Rev News). 2016; 10:591–601.ZahraQShuaibMMalikSEpidemiology of congenital anomalies in the Kurram Tribal Agency, northwest PakistanAsian Biomed (Res Rev News)201610591601Search in Google Scholar

[28]Ullah S, Dasti JI, Malik S. Descriptive epidemiology of hereditary musculoskeletal and limb defects in the isolated population of Chitral, North-West Pakistan. Pak J Med Sci. 2015; 31:1047–52.UllahSDastiJIMalikSDescriptive epidemiology of hereditary musculoskeletal and limb defects in the isolated population of Chitral, North-West PakistanPak J Med Sci20153110475210.12669/pjms.315.7594464125326648984Search in Google Scholar

[29]Jan MM. Cerebral palsy: comprehensive review and update. Ann Saudi Med. 2006; 26:123–32.JanMMCerebral palsy: comprehensive review and updateAnn Saudi Med2006261233210.5144/0256-4947.2006.123607414116761450Search in Google Scholar

[30]O’Shea TM. Diagnosis, treatment, and prevention of cerebral palsy. Clin Obstet Gynecol. 2008; 51:816–28.O’SheaTM.Diagnosis, treatment, and prevention of cerebral palsyClin Obstet Gynecol2008518162810.1097/GRF.0b013e3181870ba7305127818981805Search in Google Scholar

[31]McDermott C, White K, Bushby K, Shaw P. Hereditary spastic paraparesis: a review of new developments. J Neurol Neurosurg Psychiatry. 2000; 69:150–60.McDermottCWhiteKBushbyKShawPHereditary spastic paraparesis: a review of new developmentsJ Neurol Neurosurg Psychiatry2000691506010.1136/jnnp.69.2.150173707010896685Search in Google Scholar

[32]Fink JK. Hereditary spastic paraplegia overview. In: Pagon RA, Adam MP, Ardinger HH, editors. GeneReviews® [Internet]. Seattle: University of Washington; 1993–2017.FinkJKHereditary spastic paraplegia overviewPagonRAAdamMPArdingerHHGeneReviews® [Internet]SeattleUniversity of Washington1993–2017Search in Google Scholar

[33]Azhar MM. Helping the disabled to become respectable members of the society. Pak J Med Health Sci. 2011; 5:720–3.AzharMMHelping the disabled to become respectable members of the societyPak J Med Health Sci201157203Search in Google Scholar

[34]Jabeen N, Malik S. Consanguinity and its sociodemographic differentials in Bhimber District, Azad Jammu and Kashmir, Pakistan. J Health Popul Nutr. 2014; 32:301–13.JabeenNMalikSConsanguinity and its sociodemographic differentials in Bhimber District, Azad Jammu and Kashmir, PakistanJ Health Popul Nutr20143230113Search in Google Scholar

[35]Hina S, Malik S. Pattern of consanguinity and inbreeding coefficient in Sargodha district, Punjab, Pakistan. J Biosoc Sci. 2015; 47:803–11.HinaSMalikSPattern of consanguinity and inbreeding coefficient in Sargodha district, Punjab, PakistanJ Biosoc Sci2015478031110.1017/S002193201400043125299747Search in Google Scholar

[36]Riaz HF, Mannan S, Malik S. Consanguinity and its socio-biological parameters in Rahim Yar Khan District, Southern Punjab, Pakistan. J Health Pop Nutrition. 2016; 35:14.RiazHFMannanSMalikSConsanguinity and its socio-biological parameters in Rahim Yar Khan District, Southern Punjab, PakistanJ Health Pop Nutrition2016351410.1186/s41043-016-0049-x502602427206989Search in Google Scholar

[37]Gao J, Zhao B, He L, Sun M, Yu X, Wang L. Risk of cerebral palsy in Chinese children: AN:M matched case control study. J Paediatr Child Health. 2017; 53:464–9.GaoJZhaoBHeLSunMYuXWangLRisk of cerebral palsy in Chinese children: AN:M matched case control studyJ Paediatr Child Health201753464910.1111/jpc.1347928134474Search in Google Scholar

[38]Alexander PG, Clark KL, Tuan RS. Prenatal exposure to environmental factors and congenital limb defects. Birth Defects Res C Embryo Today. 2016; 108:243–73.AlexanderPGClarkKLTuanRSPrenatal exposure to environmental factors and congenital limb defectsBirth Defects Res C Embryo Today20161082437310.1002/bdrc.2114027768243Search in Google Scholar

[39]Brender JD, Weyer PJ. Agricultural compounds in water and birth defects. Curr Environ Health Rep. 2016; 3:144–52.BrenderJDWeyerPJAgricultural compounds in water and birth defectsCurr Environ Health Rep201631445210.1007/s40572-016-0085-027007730Search in Google Scholar

[40]Mahmood-ul-Hassan M, Suthor V, Rafique E, Ahmad R, Yasin M. Metal contamination of vegetables grown on soils irrigated with untreated municipal effluent. Bull Environ Contam Toxicol. 2012; 88:204–9.Mahmood-ul-HassanMSuthorVRafiqueEAhmadRYasinMMetal contamination of vegetables grown on soils irrigated with untreated municipal effluent. Bull Environ Contam Toxicol201288204910.1007/s00128-011-0432-722020919Search in Google Scholar

[41]Khan MU, Malik RN, Muhammad S, Ullah F, Qadir A. Health risk assessment of consumption of heavy metals in market food crops from Sialkot and Gujranwala districts, Pakistan. Hum Ecological Risk Assessment. 2015; 21:327–37.KhanMUMalikRNMuhammadSUllahFQadirAHealth risk assessment of consumption of heavy metals in market food crops from Sialkot and Gujranwala districts, PakistanHum Ecological Risk Assessment2015213273710.1080/10807039.2014.913445Search in Google Scholar

[42]Junaid M, Hashmi MZ, Malik RN. Evaluating levels and health risk of heavy metals in exposed workers from surgical instrument manufacturing industries of Sialkot, Pakistan. Environ Sci Pollut Res Int. 2016; 23:18010–26.JunaidMHashmiMZMalikRNEvaluating levels and health risk of heavy metals in exposed workers from surgical instrument manufacturing industries of Sialkot, PakistanEnviron Sci Pollut Res Int201623180102610.1007/s11356-016-6849-027255322Search in Google Scholar