<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_abm-2019-0029_s_005_w2aab3b7b3b1b6b1aab1c16b1Aa"><h3>Background</h3><p>Mortality rates of acute respiratory distress syndrome (ARDS) are different, depending on severity, etiology, and management.</p></sec><sec id="j_abm-2019-0029_s_006_w2aab3b7b3b1b6b1aab1c16b2Aa"><h3>Objective</h3><p>To determine 7-day and 28-day mortalities, hospital length of stay (LOS), duration of mechanical ventilation (MV) of ARDS patients, and factors associated with poor outcomes.</p></sec><sec id="j_abm-2019-0029_s_007_w2aab3b7b3b1b6b1aab1c16b3Aa"><h3>Methods</h3><p>A retrospective study was conducted to review the database of ARDS patients admitted in medical intensive care units (ICUs) at a university hospital between 2010 and 2014. The cases were identified by using International Classification of Diseases, 10th Revision (ICD-10) code-J80 ARDS.</p></sec><sec id="j_abm-2019-0029_s_008_w2aab3b7b3b1b6b1aab1c16b4Aa"><h3>Results</h3><p>Of 266 patients, 11.7%, 44.4%, and 44% fulfilled mild, moderate, and severe ARDS criteria, respectively. The main cause of ARDS was pneumonia. The 7-day and 28-day mortalities, median LOS, and median MV duration were 31.1%, 69.3%, 18, and 11 days, respectively. Pressure control was the most favorite mode, used with average tidal volume (TV) of 8.63 (2.16) mL/kg ideal body weight (IBW). Recruitment maneuver was most frequently used as adjunctive intervention, whereas prone position was applied to 3.75% of the patients. One-third of the patients received neuromuscular blockades. The median 7-day fluid balance was +6,600 mL. The mean PaO<sub>2</sub>/FiO<sub>2</sub> ratio during the first 3 days, cumulative fluid balance on day 3, and average daily calories during the first week were independent predictors for adjusted 7-day mortality, whereas Acute Physiology and Chronic Health Evaluation (APACHE II) score, fluid balance on day 1, cumulative fluid balance, and average daily calories during the first week were independent predictors for adjusted 28-day mortality.</p></sec><sec id="j_abm-2019-0029_s_009_w2aab3b7b3b1b6b1aab1c16b5Aa"><h3>Conclusions</h3><p>The 28-day mortality of ARDS was high. In addition, TV and fluid balance were greater than protective limits. These findings indicated the potential improvement of ARDS outcomes in our hospital.</p></sec></abstract>

BackgroundMortality rates of acute respiratory distress syndrome (ARDS) are different, depending on severity, etiology, and management.ObjectiveTo determine 7-day and 28-day mortalities, hospital length of stay (LOS), duration of mechanical ventilation (MV) of ARDS patients, and factors associated with poor outcomes.MethodsA retrospective study was conducted to review the database of ARDS patients admitted in medical intensive care units (ICUs) at a university hospital between 2010 and 2014. The cases were identified by using International Classification of Diseases, 10th Revision (ICD-10) code-J80 ARDS.ResultsOf 266 patients, 11.7%, 44.4%, and 44% fulfilled mild, moderate, and severe ARDS criteria, respectively. The main cause of ARDS was pneumonia. The 7-day and 28-day mortalities, median LOS, and median MV duration were 31.1%, 69.3%, 18, and 11 days, respectively. Pressure control was the most favorite mode, used with average tidal volume (TV) of 8.63 (2.16) mL/kg ideal body weight (IBW). Recruitment maneuver was most frequently used as adjunctive intervention, whereas prone position was applied to 3.75% of the patients. One-third of the patients received neuromuscular blockades. The median 7-day fluid balance was +6,600 mL. The mean PaO2/FiO2 ratio during the first 3 days, cumulative fluid balance on day 3, and average daily calories during the first week were independent predictors for adjusted 7-day mortality, whereas Acute Physiology and Chronic Health Evaluation (APACHE II) score, fluid balance on day 1, cumulative fluid balance, and average daily calories during the first week were independent predictors for adjusted 28-day mortality.ConclusionsThe 28-day mortality of ARDS was high. In addition, TV and fluid balance were greater than protective limits. These findings indicated the potential improvement of ARDS outcomes in our hospital.

Clinical outcomes of acute respiratory distress syndrome in a university hospital

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

BackgroundMortality rates of acute respiratory distress syndrome (ARDS) are different, depending on severity, etiology, and management.ObjectiveTo determine...

Clinical outcomes of acute respiratory distress syndrome in a university hospital

Article Category: Brief communication (original)

Published Online: Oct 24, 2019

Page range: 263 - 271

DOI: https://doi.org/10.1515/abm-2019-0029

Keywords
acute respiratory distress syndrome, intensive care units, positive pressure respiration

© 2018 Sanguanwong and Kongpolprom, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Clinical outcomes of acute respiratory distress syndrome in a university hospital

Article Category: Brief communication (original)

Published Online: Oct 24, 2019

Page range: 263 - 271

DOI: https://doi.org/10.1515/abm-2019-0029

Keywordsacute respiratory distress syndrome, intensive care units, positive pressure respiration

© 2018 Sanguanwong and Kongpolprom, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
acute respiratory distress syndrome, intensive care units, positive pressure respiration