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Recognition of tramadol abuse, dispensing practices, and opinions about its control policy among community pharmacists in Bangkok, Thailand


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Opinions of pharmacists on tramadol control policy

Opinion of pharmacistsn (%)
Practicability of policy implementation (n = 305)
Practical252 (82.6)
Not practical53 (17.4)
Ability of policy to reduce tramadol abuse problem
(n = 305)
Agreed131 (43.0)
Disagreed112 (36.7)
Not assured62 (20.3)
Scenario of rescheduling tramadol as a prescription
medicine (n = 305)
Agreed90 (29.5)
Disagreed184 (60.3)
Not assured31 (10.2)

Tramadol dispensing practices

Tramadol dispensingNumber of pharmacies/pharmacists n (%)
Dispensing of single drug (tramadol)
Number of customers (cases per week;
n = 83)
<125 (30)
1–540 (48)
6–1011 (13)
>107 (8)
Number of drugs dispensed
(tablets/capsules per patient; n = 75)
<104 (5)
10–2069 (92)
>202 (3)
Dispensing of fixed combination drug (tramadol plus acetaminophen)
Number of customers (cases per week;
n = 136)§
<174 (54)
1–555 (41)
6–104 (3)
>103 (2)
Number of drugs dispensed
(tablets/capsules per patient; n = 113)||
<107 (6)
10–20105 (93)
>201 (1)
Major reasons for dispensing (n = 185)
Supplying regular medicine along with
previous prescriptions137 (74)
Moderate-to-severe pain112 (61)
Ineffectiveness of other analgesic drugs94 (51)
Allergy to other analgesic drugs56 (30)
Precaution/contraindication to other
analgesics, e.g., renal disease and peptic
ulcer30 (16)
Combining with other analgesics, e.g.,
NSAIDs, acetaminophen, and muscle
relaxants28 (15)
Major indications for dispensing (n = 185)
Bone pain107 (58)
Cancer pain78 (42)
Back pain72 (39)
Muscle pain56 (30)
Tooth pain/pain in oral cavity31 (17)
Neuropathic pain31 (17)
Number of pharmacists giving an
explanation to customers (n = 185)
Explanation of potential side effect(s)155 (84)
Explanation of special precaution(s)96 (52)
Major side effect(s) explained (n = 155)
Nausea/vomiting95 (61)
Drowsiness/somnolence77 (50)
Dizziness71 (46)
Constipation50 (32)
Major special precaution(s) explained (n = 96)
Take only as required for pain32 (33)
Be aware of drug addiction25 (26)
Avoid long-term use18 (19)
Be aware of drug interaction9 (9)

Recognition of current tramadol abuse and announcement of the tramadol control policy

Recognition by pharmacistsn (%)
Tramadol abuse situation
Recognitions (n = 305) Know304 (99.7)
Do not know1 (0.3)
Major sources of information (n = 304)
Television news150 (49.3)
Social media135 (44.4)
Thai FDA112 (36.8)
Newspapers108 (35.5)
Patients/customers56 (18.4)
Other pharmacists45 (14.8)
Announcement of tramadol control policy
Recognitions (n = 305)
Know298 (97.7)
Do not know7 (2.3)
Major sources of information (n = 298)
Thai FDA207 (69.5)
Social media52 (17.5)
Head offices of pharmacy chain stores33 (11.1)
Other pharmacists25 (8.4)
Television news12 (4.0)
Faculties of pharmacy12 (4.0)
The experiences of pharmacists with teenagers asking for tramadol (n = 305)
Yes215 (70.5)
Number of teenagers (cases per week; n = 213)
<172 (33.8)
1–581 (38.0)
6–1029 (13.6)
>1031 (14.6)
The experiences of pharmacists with customers asking for tramadol > 20 tablets/capsules per case (n = 305)
Yes102 (33.4)
Number of customers (cases per week; n = 94)
<170 (75)
1–519 (20)
6–102 (2)
>103 (3)

Demographic data and characteristics of pharmacists and pharmacies

CharacteristicsValues
Pharmacists (n = 305)
Female190 (62.3)
Age: mean ± SD (years)36.6 ± 11.5
Full-time pharmacist238 (78.0)
Work experience in pharmacies: mean ± SD (years)8.8 ± 9.3
Pharmacies (n = 305)
Type of business
Stand-alone pharmacies216 (70.8)
Chain pharmacies89 (29.2)
Type of business channel
Retail pharmacies279 (91.5)
Both retail and wholesale pharmacies26 (8.5)
Number of customers (cases per day)
<2020 (6.6)
21–4069 (22.6)
41–6056 (18.4)
61–8047 (15.4)
81–10061 (20.0)
>10052 (17.1)
Number of customers who had pain or asked for analgesics (cases per day)
<1082 (26.9)
11–20124 (40.7)
21–3048 (15.7)
31–4025 (8.2)
41–5020 (6.6)
>506 (2.0)
Availability of tramadol
Yes185 (60.7)
No120 (39.3)
Formulation of tramadol available in 185 pharmacies
Single drug (tramadol) only30 (16)
Fixed combination drug (tramadol/acetaminophen) only97 (52)
Both formulations58 (31)
eISSN:
1875-855X
Language:
English
Publication timeframe:
6 times per year
Journal Subjects:
Medicine, Assistive Professions, Nursing, Basic Medical Science, other, Clinical Medicine