<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Surgical patients commonly develop hyperglycemia secondary to the neuroendocrine stress response. Insulin treatment of hyperglycemia is required to overcome the perioperative catabolic state and acute insulin resistance. Besides its metabolic actions on glucose metabolism, insulin also displays nonmetabolic physiological effects. Preoperative glycemic assessment, maintenance of normoglycemia, and avoidance of glucose variability are paramount to optimize surgical outcomes. This review discusses the basic physiology and effects of insulin as well as practical issues pertaining to its management during the perioperative period.</p></abstract>

Surgical patients commonly develop hyperglycemia secondary to the neuroendocrine stress response. Insulin treatment of hyperglycemia is required to overcome the perioperative catabolic state and acute insulin resistance. Besides its metabolic actions on glucose metabolism, insulin also displays nonmetabolic physiological effects. Preoperative glycemic assessment, maintenance of normoglycemia, and avoidance of glucose variability are paramount to optimize surgical outcomes. This review discusses the basic physiology and effects of insulin as well as practical issues pertaining to its management during the perioperative period.

Perioperative insulin therapy

University of Florida College of Medicine

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

{"article-title":"Perioperative insulin therapy"}

Surgical patients commonly develop hyperglycemia secondary to the neuroendocrine stress response. Insulin treatment of hyperglycemia is required to overcome...

Perioperative insulin therapy

Article Category: Review article

Published Online: Oct 10, 2018

Page range: 395 - 404

DOI: https://doi.org/10.1515/abm-2018-0014

Keywords
blood glucose, diabetes mellitus, hyperglycemia, insulins, perioperative care

© 2017 Prangmalee Leurcharusmee et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Perioperative insulin therapy

Article Category: Review article

Published Online: Oct 10, 2018

Page range: 395 - 404

DOI: https://doi.org/10.1515/abm-2018-0014

Keywordsblood glucose, diabetes mellitus, hyperglycemia, insulins, perioperative care

© 2017 Prangmalee Leurcharusmee et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
blood glucose, diabetes mellitus, hyperglycemia, insulins, perioperative care